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Genetics
Germany
2024
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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Genetics

D-Index
115
Citations
64665
World Ranking
449
National Ranking
29

Medicine

D-Index
118
Citations
69331
World Ranking
3988
National Ranking
221

Research.com Recognitions

  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award

Overview

Peter Heutink is affiliated with the German Center for Neurodegenerative Diseases in Germany. Their research spans several domains within biochemistry, genetics, molecular biology, medicine, and neuroscience, with a particular focus on molecular biology, neurology, genetics, cellular and molecular neuroscience, and physiology.

The scientist's work encompasses multiple key topics, including:

  • Parkinson's Disease Mechanisms and Treatments
  • Amyotrophic Lateral Sclerosis Research
  • RNA Research and Splicing
  • Neurological diseases and metabolism
  • Genomics and Rare Diseases
  • Nuclear Receptors and Signaling
  • CRISPR and Genetic Engineering

Among their recent publications are the following:

  • Deep learning-based cell composition analysis from tissue expression profiles, 2020, Science Advances
  • Functional annotation of human long noncoding RNAs via molecular phenotyping, 2020, Genome Research
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, Nature Communications
  • Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets, 2021, JAMA Neurology
  • LifeTime and improving European healthcare through cell-based interceptive medicine, 2020, Nature

Frequent co-authors include:

  • Cornelis Blauwendraat
  • Patrizia Rizzu
  • Mike A. Nalls
  • Andrew Singleton
  • Sara Bandrés-Ciga

The scientist has published extensively in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Journal of Human Genetics
  • Movement Disorders
  • Nature Communications
  • npj Parkinson's Disease

Peter Heutink's contributions reflect a detailed engagement with neurodegenerative diseases, especially Parkinson's disease, leveraging methods from cell-based analysis to genetic and epigenetic data integration. Their work also intersects with advanced computational techniques such as deep learning for tissue expression profiling, as illustrated in their recent publications.

Best Publications

  • A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

    Alan E. Renton;Elisa Majounie;Adrian James Waite;Javier Simón-Sánchez;Javier Simón-Sánchez

  • Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

    M. Hutton;C. L. Lendon;P. Rizzu;M. Baker

  • Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

    Vincenzo Bonifati;Vincenzo Bonifati;Patrizia Rizzu;Marijke J. van Baren;Onno Schaap

  • An atlas of active enhancers across human cell types and tissues

    Robin Andersson;Claudia Gebhard;Irene Miguel-Escalada;Ilka Hoof

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

    Mike A Nalls;Nathan Pankratz;Christina M. Lill;Chuong B. Do

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.

    Michael A Nalls;Vincent Plagnol;Dena G Hernandez

  • An atlas of human long non-coding RNAs with accurate 5′ ends

    Chung Chau Hon;Jordan A. Ramilowski;Jayson Harshbarger;Nicolas Bertin;Nicolas Bertin

  • Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy

    Brais B;Bouchard Jp;Xie Yg;Rochefort Dl

  • Somatic retrotransposition alters the genetic landscape of the human brain

    J. Kenneth Baillie;Mark W. Barnett;Kyle R. Upton;Daniel J. Gerhardt

  • DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers

    C. F. Lippa;J. E. Duda;M. Grossman;H. I. Hurtig

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study.

    Sonia M Rosso;Laura Donker Kaat;Timo Baks;Marijke Joosse

  • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.

    Christina M. Lill;Johannes T. Roehr;Johannes T. Roehr;Matthew B. McQueen;Fotini K. Kavvoura;Fotini K. Kavvoura;Fotini K. Kavvoura

  • Role of COL4A1 in small-vessel disease and hemorrhagic stroke.

    Douglas B Gould;F Campbell Phalan;Saskia E van Mil;John P Sundberg

  • A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis.

    Njajou Ot;Vaessen N;Joosse M;Berghuis B

Frequent Co-Authors

Patrizia Rizzu
Patrizia Rizzu German Center for Neurodegenerative Diseases
Ben A. Oostra
Ben A. Oostra Erasmus University Rotterdam
Alexis Brice
Alexis Brice Institut du Cerveau
Thomas Gasser
Thomas Gasser University of Tübingen
Andrew B. Singleton
Andrew B. Singleton National Institutes of Health
John Hardy
John Hardy University College London
Javier Simón-Sánchez
Javier Simón-Sánchez University of Tübingen
John C. van Swieten
John C. van Swieten Erasmus University Rotterdam
Dena G. Hernandez
Dena G. Hernandez National Institutes of Health
Nicholas W. Wood
Nicholas W. Wood University College London

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