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Molecular Biology

D-Index
53
Citations
25658
World Ranking
2353
National Ranking
157

Overview

Patrizia Rizzu is affiliated with the German Center for Neurodegenerative Diseases in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to subfields such as Molecular Biology, Neurology, Genetics, Physiology, and Cellular and Molecular Neuroscience.

The scientist's work covers a range of topics within neurodegenerative and molecular biology research, including:

  • Amyotrophic Lateral Sclerosis Research
  • Epigenetics and DNA Methylation
  • Alzheimer's disease research and treatments
  • RNA Research and Splicing
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pluripotent Stem Cells Research
  • RNA modifications and cancer

Patrizia Rizzu has contributed to multiple peer-reviewed papers, among which the following recent publications stand out:

  • Functional annotation of human long noncoding RNAs via molecular phenotyping, 2020, published in Genome Research
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, published in Nature Communications
  • Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS, 2024, published in Nature Medicine
  • The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism, 2023, published in Cell Genomics
  • Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information, 2020, published in Nature Communications

Their research has been disseminated predominantly through specific scientific venues. Frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Genome Research
  • Journal of Visualized Experiments
  • Nature Medicine

Patrizia Rizzu has collaborated frequently with several researchers in the field. Notable co-authors comprise:

  • Peter Heutink
  • Cornelis Blauwendraat
  • David W. Craig
  • Noémia Fernandes
  • Ashutosh Dhingra

Best Publications

  • Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

    M. Hutton;C. L. Lendon;P. Rizzu;M. Baker

  • Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

    Vincenzo Bonifati;Vincenzo Bonifati;Patrizia Rizzu;Marijke J. van Baren;Onno Schaap

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Somatic retrotransposition alters the genetic landscape of the human brain

    J. Kenneth Baillie;Mark W. Barnett;Kyle R. Upton;Daniel J. Gerhardt

  • An integrated expression atlas of miRNAs and their promoters in human and mouse.

    Derek De Rie;Imad Abugessaisa;Tanvir Alam;Erik Arner

  • High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands

    Patrizia Rizzu;John C. Van Swieten;Marijke Joosse;Masato Hasegawa

  • DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism.

    V. Bonifati;V. Bonifati;P. Rizzu;F. Squitieri;E. Krieger

  • Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

    P.F. Sullivan;E.J.C. de Geus;G. Willemsen;M.R. James

  • Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

    Della C. David;Susanne Hauptmann;Isabel Scherping;Katrin Schuessel

  • Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

    L.A. Robak;L.A. Robak;I.E. Jansen;I.E. Jansen;J van Rooij;A.G. Uitterlinden

  • β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease

    Shuchi Mittal;Kjetil Bjørnevik;Kjetil Bjørnevik;Doo Soon Im;Adrian Flierl

  • Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy.

    Suzanne Lesage;Valérie Drouet;Elisa Majounie;Vincent Deramecourt

  • Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics

    I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt

  • Frontotemporal dementia and its subtypes: a genome-wide association study

    Raffaele Ferrari;Raffaele Ferrari;Dena G Hernandez;Dena G Hernandez;Michael A Nalls;Jonathan D Rohrer

  • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

    A. Beilina;I. N. Rudenko;A. Kaganovich;L. Civiero

  • Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.

    Marc Meulener;Alexander J. Whitworth;Cecilia E. Armstrong-Gold;Patrizia Rizzu

  • A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease

    V. Plagnol;M.A. Nalls;J.M. Bras;D.G. Hernandez;D.G. Hernandez

  • Phenotypic variation in hereditary frontotemporal dementia with tau mutations

    J. C. Van Swieten;M. Stevens;S. M. Rosso;P. Rizzu

  • Distinct genetic forms of frontotemporal dementia.

    H. Seelaar;W. Kamphorst;S. M. Rosso;A. Azmani

Frequent Co-Authors

Peter Heutink
Peter Heutink German Center for Neurodegenerative Diseases
Javier Simón-Sánchez
Javier Simón-Sánchez University of Tübingen
John C. van Swieten
John C. van Swieten Erasmus University Rotterdam
Dena G. Hernandez
Dena G. Hernandez National Institutes of Health
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Frank Brombacher
Frank Brombacher University of Cape Town
Juha Kere
Juha Kere Karolinska Institute

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