Her primary areas of study are Cell biology, Immunology, Antigen presentation, Antigen and Interleukin 12. Her Cell biology research integrates issues from Receptor, Dendritic cell, T cell and CD40. Marina Cella combines subjects such as TREM2 and PI3K/AKT/mTOR pathway with her study of Receptor.
Her Antigen presentation study combines topics in areas such as Molecular biology, C-C chemokine receptor type 7 and Major histocompatibility complex, MHC class II. She studies Plasmacytoid dendritic cell, a branch of Antigen. The concepts of her Interleukin 12 study are interwoven with issues in Antigen-presenting cell, Natural killer T cell, Natural killer cell, Interleukin 21 and Interferon gamma.
The scientist’s investigation covers issues in Cell biology, Immunology, Receptor, Molecular biology and T cell. She has included themes like Dendritic cell, Antigen, Interleukin 12 and Interleukin 21 in her Cell biology study. Her work in Antigen tackles topics such as Antigen presentation which are related to areas like Major histocompatibility complex.
Her study connects Natural killer cell and Immunology. Her work on Signal transducing adaptor protein as part of general Receptor study is frequently linked to TLR9, therefore connecting diverse disciplines of science. Her studies in T cell integrate themes in fields like Priming and CD3, CD8.
Cell biology, Immunology, Innate lymphoid cell, Receptor and Immune system are her primary areas of study. Marina Cella is interested in Signal transduction, which is a branch of Cell biology. Immunology is closely attributed to Natural killer cell in her study.
Her Receptor research incorporates themes from Tumor necrosis factor alpha, Cancer research, Cytokine and TREM2, Microglia. She works mostly in the field of Immune system, limiting it down to topics relating to Cell type and, in certain cases, Antigen-presenting cell and Myeloid, as a part of the same area of interest. Her study focuses on the intersection of T cell and fields such as CD8 with connections in the field of Cytotoxic T cell.
Her primary scientific interests are in Cell biology, Immunology, TREM2, Microglia and Innate lymphoid cell. Specifically, her work in Cell biology is concerned with the study of Signal transduction. Her work deals with themes such as Cell survival, Receptor, Lipid sensing and Alzheimer's disease, Disease, which intersect with TREM2.
The various areas that Marina Cella examines in her Receptor study include Autophagy, Endocrinology, Molecular biology, T-cell receptor and Intraepithelial lymphocyte. Her Microglia study incorporates themes from PI3K/AKT/mTOR pathway, Endoplasmic reticulum, Neurodegeneration and Intracellular. The Innate lymphoid cell study combines topics in areas such as Transcriptome, Transcription factor, Gene, Growth factor and Transforming growth factor.
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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
M Cella;D Scheidegger;K Palmer-Lehmann;P Lane.
Journal of Experimental Medicine (1996)
Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.
Federica Sallusto;Marina Cella;Carlo Danieli;Antonio Lanzavecchia.
Journal of Experimental Medicine (1995)
Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon.
Marina Cella;David Jarrossay;Fabio Facchetti;Olga Alebardi.
Nature Medicine (1999)
Origin, maturation and antigen presenting function of dendritic cells
Marina Cella;Federica Sallusto;Antonio Lanzavecchia.
Current Opinion in Immunology (1997)
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
Marina Cella;Anneke Engering;Valerie Pinet;Jean Pieters.
Serial triggering of many T-cell receptors by a few peptide–MHC complexes
Salvatore Valitutti;Sabina Müller;Marina Cella;Elisabetta Padovan.
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
Marina Cella;Anja Fuchs;William Vermi;Fabio Facchetti.
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
Leonid Gitlin;Winfried Barchet;Susan Gilfillan;Marina Cella.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.
Marina Cella;Fabio Facchetti;Antonio Lanzavecchia;Marco Colonna.
Nature Immunology (2000)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
Yaming Wang;Yaming Wang;Marina Cella;Kaitlin Mallinson;Jason D. Ulrich.
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