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Andrey S. Shaw

Andrey S. Shaw

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
40735
World Ranking
1641
National Ranking
919

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Andrey S. Shaw is affiliated with Genentech in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research covers several subfields, including Molecular Biology, Immunology, Nephrology, Radiology, Nuclear Medicine and Imaging, and Oncology.

Their work has focused on key scientific topics such as:

  • Renal Diseases and Glomerulopathies
  • Renal and related cancers
  • Chronic Kidney Disease and Diabetes
  • Alzheimer's disease research and treatments
  • MRI in cancer diagnosis
  • Single-cell and spatial transcriptomics
  • Melanoma and MAPK Pathways

Among recent publications, notable papers include:

  • "Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury" (2020) in the Journal of the American Society of Nephrology
  • "The Mesangial cell - the glomerular stromal cell" (2021) in Nature Reviews Nephrology
  • "Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization" (2020) in Nature Structural & Molecular Biology
  • "Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues" (2021) in Nature Immunology
  • "CRAF dimerization with ARAF regulates KRAS-driven tumor growth" (2022) in Cell Reports

Shaw has collaborated frequently with several coauthors, including Ben Korin, Joshua D. Webster, Shimrit Avraham, Zora Modrušan, and Hans D. Brightbill.

Their articles have appeared regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Society of Nephrology, Nature Communications, Nature Immunology, and proceedings of the International Society for Magnetic Resonance in Medicine's scientific meeting and exhibition.

In addition to articles, Shaw has published work through The MIT Press, including the book "Viruses, Pandemics, and Immunity" (2021).

Recognition includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

    Arash Grakoui;Shannon K. Bromley;Cenk Sumen;Mark M. Davis

  • Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.

    Cheng Yuan Peng;Paul R. Graves;Richard S. Thoma;Zhiqi Wu

  • Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine.

    Anthony J Muslin;Anthony J Muslin;J.William Tanner;Paul M Allen;Andrey S Shaw

  • The immunological synapse.

    S K Bromley;W R Burack;K G Johnson;K Somersalo

  • Congenital Nephrotic Syndrome in Mice Lacking CD2-Associated Protein

    Neng-Yao Shih;Jun Li;Vladimir Karpitskii;Ancho Nguyen

  • T Cell Receptor Signaling Precedes Immunological Synapse Formation

    Kyeong-Hee Lee;Amy D. Holdorf;Michael L. Dustin;Andrew C. Chan

  • A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

    Michael L Dustin;Michael W Olszowy;Amy D Holdorf;Jun Li

  • Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

    Karin Schwarz;Matias Simons;Jochen Reiser;Moin A. Saleem

  • Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

    Björn Hartleben;Markus Gödel;Catherine Meyer-Schwesinger;Shuya Liu

  • PARTIAL T CELL SIGNALING : ALTERED PHOSPHO-ZETA AND LACK OF ZAP70 RECRUITMENT IN APL-INDUCED T CELL ANERGY

    Joanne Sloan-Lancaster;Andrey S. Shaw;Jonathan B. Rothbard;Paul M. Allen

  • The immunological synapse balances T cell receptor signaling and degradation.

    Kyeong-Hee Lee;Kyeong-Hee Lee;Aaron R. Dinner;Chun Tu;Gabriele Campi

  • CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.

    Jeong M. Kim;Hui Wu;Gopa Green;Cheryl A. Winkler

  • Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation

    Andrey S. Shaw;Michael L. Dustin

  • Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation

    Amanda L. Blasius;Emanuele Giurisato;Marina Cella;Robert D. Schreiber

  • The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

    Andrey S. Shaw;Kurt E. Amrein;Craig Hammond;David F. Stern

  • Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.

    Tobias B. Huber;Björn Hartleben;Jeong Kim;Miriam Schmidts

  • Signal transduction: hanging on a scaffold.

    W Richard Burack;Andrey S Shaw

  • Fidelity of T Cell Activation Through Multistep T Cell Receptor ζ Phosphorylation

    Ellen Neumeister Kersh;Andrey S. Shaw;Paul M. Allen

  • CD2AP Localizes to the Slit Diaphragm and Binds to Nephrin via a Novel C-Terminal Domain

    Neng-Yao Shih;Jun Li;Ramzi Cotran;Peter Mundel

  • Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by Interacting with the Poliovirus Receptor (CD155)

    Anja Fuchs;Marina Cella;Emanuele Giurisato;Andrey S. Shaw

Frequent Co-Authors

Jeffrey H. Miner
Jeffrey H. Miner Washington University in St. Louis
Paul M. Allen
Paul M. Allen Washington University in St. Louis
Michael L. Dustin
Michael L. Dustin University of Oxford
Tobias B. Huber
Tobias B. Huber Universität Hamburg
Marco Colonna
Marco Colonna Washington University in St. Louis
Jeffrey B. Kopp
Jeffrey B. Kopp National Institutes of Health
Marina Cella
Marina Cella Washington University in St. Louis
Susan S. Taylor
Susan S. Taylor University of California, San Diego
Robert D. Schreiber
Robert D. Schreiber Washington University in St. Louis

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