His primary areas of investigation include Thyrotropin receptor, Endocrinology, Internal medicine, Molecular biology and Receptor. His Thyrotropin receptor research is multidisciplinary, incorporating elements of Chinese hamster ovary cell, Glycosylation, Protein subunit, Ectodomain and Peptide sequence. His study in Endocrinology is interdisciplinary in nature, drawing from both Immunoglobulin G and Antibody.
His Internal medicine research integrates issues from Humoral immunity and Cyclic nucleotide. The study incorporates disciplines such as cDNA library and Thyroid peroxidase in addition to Molecular biology. His studies deal with areas such as Transmembrane domain, Expression vector and Signal peptide as well as cDNA library.
His primary scientific interests are in Endocrinology, Internal medicine, Molecular biology, Thyroid peroxidase and Thyroid. His Receptor research extends to the thematically linked field of Endocrinology. Many of his research projects under Internal medicine are closely connected to TRH stimulation test with TRH stimulation test, tying the diverse disciplines of science together.
His Molecular biology research integrates issues from Chinese hamster ovary cell and Complementary DNA, cDNA library, Gene, Transfection. The concepts of his Chinese hamster ovary cell study are interwoven with issues in Thyrotropin receptor and Recombinant DNA, Expression vector. His work in Thyroid peroxidase addresses issues such as Autoantibody, which are connected to fields such as Monoclonal.
Basil Rapoport focuses on Thyroid peroxidase, Internal medicine, Endocrinology, Molecular biology and Antibody. His Thyroid peroxidase study combines topics in areas such as Immunoglobulin gene, Thyroiditis, Autoantibody, Epitope and Thyroglobulin. His biological study spans a wide range of topics, including T cell and Autoimmune disease.
His work deals with themes such as Chinese hamster ovary cell, Thyrotropin receptor, Mutation, Protein subunit and Protein structure, which intersect with Molecular biology. His Thyrotropin receptor research includes themes of Receptor, Cleavage, Biochemistry and Glycosylation. His research in Antibody intersects with topics in Gene, Oligonucleotide Primer and Antigen.
Thyrotropin receptor, Internal medicine, Endocrinology, Molecular biology and Autoantibody are his primary areas of study. In his study, Cell and Lectin is inextricably linked to Ectodomain, which falls within the broad field of Thyrotropin receptor. His study in Internal medicine is interdisciplinary in nature, drawing from both Mutation, Point mutation, Recombinant DNA and Complementary DNA.
His Endocrinology study integrates concerns from other disciplines, such as genomic DNA, Humoral immunity, Aldesleukin and Exon. His Molecular biology research is multidisciplinary, incorporating perspectives in Receptor, Chinese hamster ovary cell, Protein subunit and Glycosylation. His studies examine the connections between Autoantibody and genetics, as well as such issues in Thyroid peroxidase, with regards to Graves' disease.
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Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
Yuji Nagayama;Keith D. Kaufman;Keith D. Kaufman;Pui Seto;Pui Seto;Basil Rapoport;Basil Rapoport.
Biochemical and Biophysical Research Communications (1989)
Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette".
S Portolano;G D Chazenbalk;J S Hutchison;S M McLachlan.
Journal of Immunology (1993)
The thyrotropin receptor 25 years after its discovery: new insight after its molecular cloning.
Yuji Nagayama;Basil Rapoport.
Molecular Endocrinology (1992)
The molecular biology of thyroid peroxidase: cloning, expression and role as autoantigen in autoimmune thyroid disease.
Sandra M. McLACHLAN;Basil Rapoport.
Endocrine Reviews (1992)
Human organ-specific autoimmune disease. Molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic immunodominant region and restricted immunoglobulin gene usage in the target organ.
G D Chazenbalk;S Portolano;D Russo;J S Hutchison.
Journal of Clinical Investigation (1993)
Molecular cloning of the complementary deoxyribonucleic acid for human thyroid peroxidase.
Ronald P. Magnusson;Gregorio D. Chazenbalk;Jane Gestautas;Pui Seto.
Molecular Endocrinology (1987)
Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.
Y Nagayama;H L Wadsworth;D Russo;G D Chazenbalk.
Journal of Clinical Investigation (1991)
Engineering the Human Thyrotropin Receptor Ectodomain from a Non-secreted Form to a Secreted, Highly Immunoreactive Glycoprotein That Neutralizes Autoantibodies in Graves' Patients' Sera
Gregorio D. Chazenbalk;Juan Carlos Jaume;Sandra M. McLachlan;Basil Rapoport.
Journal of Biological Chemistry (1997)
Genetic alterations in thyroid hyperfunctioning adenomas.
D Russo;F Arturi;R Wicker;G D Chazenbalk.
The Journal of Clinical Endocrinology and Metabolism (1995)
Thyroid-stimulating immunoglobulin bioassay using cultured human thyroid cells.
W. E. Hinds;N. Takai;B. Rapoport;S. Filetti.
The Journal of Clinical Endocrinology and Metabolism (1981)
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