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Biology and Biochemistry

D-Index
69
Citations
16437
World Ranking
7423
National Ranking
3386

Overview

Basil Rapoport is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on medicine, with an emphasis on endocrinology, diabetes, and metabolism. Additional areas of study include oncology, immunology, physiology, and genetics.

Their work spans several interconnected topics, such as thyroid disorders and treatments, cancer immunotherapy and biomarkers, immunotherapy and immune responses, CAR-T cell therapy research, thyroid cancer diagnosis and treatment, erythrocyte function and pathophysiology, as well as diabetes and associated disorders.

Recent significant publications by Basil Rapoport include the following:

  • Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity, 2020, Cancer Immunology Immunotherapy
  • Discoveries in Thyroid Autoimmunity in the Past Century, 2022, Thyroid
  • ATA Centennial Interview Series: History of Thyroid Autoimmunity, 2023, VideoEndocrinology

Frequent co-authors collaborating with Basil Rapoport include:

  • Sandra M. McLachlan
  • Airi Harui
  • Thomas I. Zarembinski
  • Michael D. Roth
  • Gregory A. Brent

Publications have appeared in venues such as:

  • Cancer Immunology Immunotherapy
  • Thyroid
  • VideoEndocrinology

Best Publications

  • The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies

    Basil Rapoport;Gregorio D. Chazenbalk;Juan Carlos Jaume;Sandra M. McLachlan

  • Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor

    Yuji Nagayama;Keith D. Kaufman;Keith D. Kaufman;Pui Seto;Pui Seto;Basil Rapoport;Basil Rapoport

  • Mechanisms of Autoantibody-Induced Pathology.

    Ralf J. Ludwig;Karen Vanhoorelbeke;Frank Leypoldt;Ziya Kaya

  • Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette".

    S Portolano;G D Chazenbalk;J S Hutchison;S M McLachlan

  • The thyrotropin receptor 25 years after its discovery: new insight after its molecular cloning.

    Yuji Nagayama;Basil Rapoport

  • The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim

    Chun-Rong Chen;Pavel Pichurin;Yuji Nagayama;Francesco Latrofa

  • The molecular biology of thyroid peroxidase: cloning, expression and role as autoantigen in autoimmune thyroid disease.

    Sandra M. McLACHLAN;Basil Rapoport

  • Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

    Sandra M. McLachlan;Basil Rapoport

  • Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa.

    Sandra M. McLachlan;Basil Rapoport

  • Human organ-specific autoimmune disease. Molecular cloning and expression of an autoantibody gene repertoire for a major autoantigen reveals an antigenic immunodominant region and restricted immunoglobulin gene usage in the target organ.

    G D Chazenbalk;S Portolano;D Russo;J S Hutchison

  • Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor

    Gregorio D. Chazenbalk;Pavel Pichurin;Chun-Rong Chen;Francesco Latrofa

  • The thyrotropin receptor in Graves' disease.

    Basil Rapoport;Sandra M. McLachlan

  • Insight into Graves' hyperthyroidism from animal models.

    Sandra M. McLachlan;Yuji Nagayama;Basil Rapoport

  • An insertion in the human thyrotropin receptor critical for high affinity hormone binding.

    Harry L. Wadsworth;Gregorio D. Chazenbalk;Yuji Nagayama;Diego Russo

  • Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.

    Y Nagayama;H L Wadsworth;D Russo;G D Chazenbalk

  • Molecular cloning of the complementary deoxyribonucleic acid for human thyroid peroxidase.

    Ronald P. Magnusson;Gregorio D. Chazenbalk;Jane Gestautas;Pui Seto

  • The Link between Graves’ Disease and Hashimoto’s Thyroiditis: A Role for Regulatory T Cells

    Sandra M. McLachlan;Yuji Nagayama;Pavel N. Pichurin;Yumiko Mizutori

  • Why measure thyroglobulin autoantibodies rather than thyroid peroxidase autoantibodies

    Sandra M. McLachlan;Basil Rapoport

  • Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease.

    Basil Rapoport;Randa Alsabeh;David Aftergood;Sandra M. McLachlan

  • Engineering the Human Thyrotropin Receptor Ectodomain from a Non-secreted Form to a Secreted, Highly Immunoreactive Glycoprotein That Neutralizes Autoantibodies in Graves' Patients' Sera

    Gregorio D. Chazenbalk;Juan Carlos Jaume;Sandra M. McLachlan;Basil Rapoport

Frequent Co-Authors

Sandra M. McLachlan
Sandra M. McLachlan University of California, Los Angeles
Sebastiano Filetti
Sebastiano Filetti Sapienza University of Rome
Leslie J. DeGroot
Leslie J. DeGroot University of Chicago
Marco Londei
Marco Londei University College London
Marc Feldmann
Marc Feldmann University of Oxford
Wilmar M. Wiersinga
Wilmar M. Wiersinga University of Amsterdam
Orlo H. Clark
Orlo H. Clark University of California, San Francisco
Noel R. Rose
Noel R. Rose Brigham and Women's Hospital
Anthony P. Weetman
Anthony P. Weetman University of Sheffield

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