D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 58 Citations 9,439 197 World Ranking 1305 National Ranking 553

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Antibody
  • Immune system

Her scientific interests lie mostly in Internal medicine, Endocrinology, Autoantibody, Immunology and Antibody. Her study connects Anti-thyroid autoantibodies and Internal medicine. Her Endocrinology research incorporates themes from Humoral immunity, Aldesleukin and B cell.

The concepts of her Autoantibody study are interwoven with issues in Epitope, Molecular biology, Thyroid peroxidase and Blocking antibody. Her Immunology research incorporates elements of Graves' disease, Disease and Pokeweed mitogen. Her Antibody research is multidisciplinary, incorporating elements of Major histocompatibility complex and Antigen.

Her most cited work include:

  • Autoantibodies to the thyrotropin receptor. (520 citations)
  • The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies (481 citations)
  • Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette". (283 citations)

What are the main themes of her work throughout her whole career to date?

Sandra M. McLachlan spends much of her time researching Endocrinology, Internal medicine, Immunology, Antibody and Autoantibody. Her studies examine the connections between Endocrinology and genetics, as well as such issues in Major histocompatibility complex, with regards to Disease. Her Internal medicine research incorporates elements of Cell culture and Genetic linkage.

She interconnects Graves' disease, Thyroid and Thyroiditis in the investigation of issues within Immunology. The Antibody study combines topics in areas such as Molecular biology, Immune system and Antigen. Her work in Autoantibody covers topics such as Thyroid peroxidase which are related to areas like Immunoglobulin gene and Phage display.

She most often published in these fields:

  • Endocrinology (49.83%)
  • Internal medicine (49.83%)
  • Immunology (50.87%)

What were the highlights of her more recent work (between 2006-2021)?

  • Endocrinology (49.83%)
  • Internal medicine (49.83%)
  • Thyroid (35.29%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Endocrinology, Internal medicine, Thyroid, Immunology and Thyrotropin receptor. Her study in Endocrinology is interdisciplinary in nature, drawing from both Receptor, Genetics and Genetic linkage. Her work in Internal medicine addresses issues such as Recombinant DNA, which are connected to fields such as Free thyroxine.

Her Thyroid study combines topics from a wide range of disciplines, such as Anti-thyroid autoantibodies and Stimulation. Sandra M. McLachlan has included themes like Genetically modified mouse and Graves' disease, Disease in her Immunology study. The various areas that Sandra M. McLachlan examines in her Thyrotropin receptor study include Transgene, Molecular biology, Epitope, Protein structure and Monoclonal antibody.

Between 2006 and 2021, her most popular works were:

  • Vitamin D Deficiency in Mice Impairs Colonic Antibacterial Activity and Predisposes to Colitis (185 citations)
  • Mechanisms of Autoantibody-Induced Pathology. (169 citations)
  • Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. (106 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Antibody
  • Immune system

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Immunology, Thyrotropin receptor and Thyroid. Her work deals with themes such as Epitope and Antibody, which intersect with Internal medicine. Her study in Antibody focuses on Autoantibody in particular.

The study incorporates disciplines such as Thyroid function and Graves' disease, Disease in addition to Immunology. Her work carried out in the field of Thyrotropin receptor brings together such families of science as Plasma protein binding, Transmembrane domain, Receptor, Ectodomain and Signal transduction. Her studies in Thyroid peroxidase integrate themes in fields like T cell and Autoimmunity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Autoantibodies to the thyrotropin receptor.

Bernard Rees Smith;Sandra Melissa McLACHLAN;Jadwiga Furmaniak.
Endocrine Reviews (1988)

805 Citations

The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies

Basil Rapoport;Gregorio D. Chazenbalk;Juan Carlos Jaume;Sandra M. McLachlan.
Endocrine Reviews (1998)

742 Citations

Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain "roulette".

S Portolano;G D Chazenbalk;J S Hutchison;S M McLachlan.
Journal of Immunology (1993)

433 Citations

Carbimazole and the autoimmune response in Graves' disease.

Alan M. McGregor;Meryl M. Petersen;Sandra M. McLachlan;Patricia Rooke.
The New England Journal of Medicine (1980)

337 Citations

Cyclosporin A promotes spontaneous outgrowth in vitro of Epstein-Barr virus-induced B-cell lines.

A. Graham Bird;Sandra M. McLachlan;Sven Britton.
Nature (1981)

304 Citations

The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim

Chun-Rong Chen;Pavel Pichurin;Yuji Nagayama;Francesco Latrofa.
Journal of Clinical Investigation (2003)

267 Citations

The molecular biology of thyroid peroxidase: cloning, expression and role as autoantigen in autoimmune thyroid disease.

Sandra M. McLACHLAN;Basil Rapoport.
Endocrine Reviews (1992)

260 Citations

Highly sensitive assays of autoantibodies to thyroglobulin and to thyroid peroxidase.

K Beever;J Bradbury;D Phillips;S M McLachlan.
Clinical Chemistry (1989)

256 Citations

Vitamin D Deficiency in Mice Impairs Colonic Antibacterial Activity and Predisposes to Colitis

Venu Lagishetty;Alexander V. Misharin;Nancy Q. Liu;Thomas S. Lisse.
Endocrinology (2010)

233 Citations

Mechanisms of Autoantibody-Induced Pathology.

Ralf J. Ludwig;Karen Vanhoorelbeke;Frank Leypoldt;Ziya Kaya.
Frontiers in Immunology (2017)

221 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Sandra M. McLachlan

Terry F. Davies

Terry F. Davies

Icahn School of Medicine at Mount Sinai

Publications: 101

Anthony P. Weetman

Anthony P. Weetman

University of Sheffield

Publications: 56

Terry J. Smith

Terry J. Smith

University of Michigan–Ann Arbor

Publications: 51

Gilbert Vassart

Gilbert Vassart

Université Libre de Bruxelles

Publications: 42

Yuji Nagayama

Yuji Nagayama

Nagasaki University

Publications: 41

Aldo Pinchera

Aldo Pinchera

University of Pisa

Publications: 37

Ralf Ludwig

Ralf Ludwig

University of Lübeck

Publications: 31

Sabine Costagliola

Sabine Costagliola

Université Libre de Bruxelles

Publications: 29

Laszlo Hegedüs

Laszlo Hegedüs

Odense University Hospital

Publications: 25

Martin Hewison

Martin Hewison

University of Birmingham

Publications: 22

Gerd Krause

Gerd Krause

Leibniz Institute for Neurobiology

Publications: 22

Paolo Vitti

Paolo Vitti

University of Pisa

Publications: 21

Leslie J. DeGroot

Leslie J. DeGroot

University of Chicago

Publications: 21

Basil Rapoport

Basil Rapoport

University of California, San Francisco

Publications: 20

Bellur S. Prabhakar

Bellur S. Prabhakar

University of Illinois at Chicago

Publications: 19

Yehuda Shoenfeld

Yehuda Shoenfeld

Sheba Medical Center

Publications: 18

Trending Scientists

Timothy C. Lethbridge

Timothy C. Lethbridge

University of Ottawa

Hans Georg Gemünden

Hans Georg Gemünden

Technical University of Berlin

Stanislav Karapetrovic

Stanislav Karapetrovic

University of Alberta

Jean-Daniel Boissonnat

Jean-Daniel Boissonnat

Université Côte d'Azur

Reiner Kraft

Reiner Kraft

Yahoo (United States)

S. De Gendt

S. De Gendt

KU Leuven

Yong-Ping Zheng

Yong-Ping Zheng

Hong Kong Polytechnic University

Charles A. Laughton

Charles A. Laughton

University of Nottingham

Hong Lin

Hong Lin

Tsinghua University

Jun Zhang

Jun Zhang

Nanyang Technological University

Francisca López-Granados

Francisca López-Granados

Spanish National Research Council

Yan Zhang

Yan Zhang

Beijing Normal University

Carl A. K. Borrebaeck

Carl A. K. Borrebaeck

Lund University

Andrea B. Troxel

Andrea B. Troxel

New York University

Joel L. Weissfeld

Joel L. Weissfeld

University of Pittsburgh

Eyal Sheiner

Eyal Sheiner

Ben-Gurion University of the Negev

Something went wrong. Please try again later.