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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
71
Citations
17742
World Ranking
2200
National Ranking
99

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

Charles Theillet is affiliated with the University of Montpellier in France, contributing primarily to the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research spans a total of 31 publications in biochemistry, genetics, and molecular biology, alongside 21 papers in medical sciences. Within these broad disciplines, Theillet has developed expertise in subfields including Molecular Biology, Oncology, Genetics, Cell Biology, and Radiology, Nuclear Medicine and Imaging.

Theillet's research addresses several main topics related to cancer biology and molecular mechanisms. These include:

  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Genomics and Chromatin Dynamics
  • BRCA gene mutations in cancer
  • Epigenetics and DNA Methylation
  • Cancer-related Molecular Pathways
  • Monoclonal and Polyclonal Antibodies Research

Frequent coauthors collaborating with Theillet are William Jacot, Béatrice Orsetti, Esin Orhan, Carolina Velázquez, and Imène Tabet, reflecting ongoing partnerships in related molecular oncology and genetics research.

Theillet has published in several venues, including bioRxiv (Cold Spring Harbor Laboratory) with 4 publications, Cancers with 2 papers, as well as the International Journal of Molecular Sciences and Pancreatology each featuring 2 contributions. They also published work in Nature Communications.

Recent papers provide insight into the thematic breadth and specific focuses of Theillet's research:

  • "A predictable conserved DNA base composition signature defines human core DNA replication origins," 2020, Nature Communications
  • "BRCA1 Promoter Hypermethylation is Associated with Good Prognosis and Chemosensitivity in Triple-Negative Breast Cancer," 2020, Cancers
  • "Regulation of RAD51 at the Transcriptional and Functional Levels: What Prospects for Cancer Therapy?", 2021, Cancers
  • "Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma," 2020, Science Translational Medicine
  • "In high-grade ovarian carcinoma, platinum-sensitive tumor recurrence and acquired-resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and SOX2," 2022, The Journal of Pathology

Best Publications

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.

    Magali Olivier;Anita Langerød;Patrizia Carrieri;Jonas Bergh

  • Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.

    Chantal Escot;Charles Theillet;Rosette Lidereau;Frederique Spyratos

  • Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

    Sandie Tuduri;Sandie Tuduri;Laure Crabbé;Chiara Conti;Hélène Tourrière

  • EMSY Links the BRCA2 Pathway to Sporadic Breast and Ovarian Cancer

    Luke Hughes-Davies;David Huntsman;Margarida Ruas;Francois Fuks

  • Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia

    Iqbal Unnisa Ali;Rosette Lidereau;Charles Theillet;Robert Callahan

  • BEK and FLG, two receptors to members of the FGF family, are amplified in subsets of human breast cancers.

    Adnane J;Gaudray P;Dionne Ca;Crumley G

  • A refined molecular taxonomy of breast cancer

    M Guedj;L Marisa;A de Reynies;B Orsetti

  • Snail and Slug Play Distinct Roles during Breast Carcinoma Progression

    Christophe Côme;Fabrice Magnino;Frédéric Bibeau;Pascal De Santa Barbara

  • In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity.

    S Bautista;H Vallès;R L Walker;S Anzick

  • Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups.

    Frank Courjal;Marguerite Cuny;Joelle Simony-Lafontaine;Geneviève Louason

  • Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas.

    Charles Theillet;Rosette Lidereau;Chantal Escot;Paula Hutzell

  • Comprehensive Profiling of 8p11-12 Amplification in Breast Cancer

    Véronique Gelsi-Boyer;Béatrice Orsetti;Nathalie Cervera;Pascal Finetti

  • Protocols for an improved detection of point mutations by SSCP

    Laura Spinardi;Raoul Mazars;Charles Theillet

  • p53 gene mutations in human epithelial skin cancers.

    J P Molès;C Moyret;B Guillot;P Jeanteur

  • Cyclin gene amplification and overexpression in breast and ovarian cancers: evidence for the selection of cyclin D1 in breast and cyclin E in ovarian tumors

    Frank Courjal;Geneviève Louason;Paul Speiser;Dionisios Katsaros

  • Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene

    Selma El Messaoudi;Eric Fabbrizio;Carmen Rodriguez;Paul Chuchana

  • A gene expression signature that can predict the recurrence of tamoxifen-treated primary breast cancer

    Maïa Chanrion;Vincent Negre;Hélène Fontaine;Nicolas Salvetat

  • TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc‐binding domains

    Anne‐Lise ‐L Børresen;Tone Ikdahl Andersen;Jorunn E. Eyfjörd;Renee S. Cornelis

  • Proto-oncogene amplification and human breast tumor phenotype.

    J Adnane;P Gaudray;M P Simon;J Simony-Lafontaine

Frequent Co-Authors

Rosette Lidereau
Rosette Lidereau Institute Curie
Jocelyne Jacquemier
Jocelyne Jacquemier Grenoble Alpes University
Robert Callahan
Robert Callahan National Institutes of Health
Evgeny N. Imyanitov
Evgeny N. Imyanitov Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences
Jacques Colinge
Jacques Colinge University of Montpellier
André Pèlegrin
André Pèlegrin University of Montpellier
Claude Sardet
Claude Sardet University of Montpellier
Dionyssios Katsaros
Dionyssios Katsaros University of Turin
Richard Redon
Richard Redon University of Nantes

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