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Biology and Biochemistry

D-Index
51
Citations
7772
World Ranking
17325
National Ranking
743

Overview

André Pèlegrin is affiliated with the University of Montpellier in France and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work focuses on key subfields including Oncology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, Biotechnology, and Reproductive Medicine.

The scientific contributions of André Pèlegrin have appeared in several specialized venues. Frequent publication outlets include:

  • Cancers
  • Clinical Cancer Research
  • Scientific Reports
  • JAMA Network Open
  • mAbs

Their research topics emphasize monoclonal and polyclonal antibodies research, HER2/EGFR in cancer research, and cancer research and treatments. Other notable topics covered are peptidase inhibition and analysis, cancer cells and metastasis, radiopharmaceutical chemistry and applications, and lung cancer treatments and mutations.

Key recent publications by André Pèlegrin include:

  • "Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111In-Labeled SGM-101," 2020, published in Clinical Cancer Research
  • "Improving Patients' Life Quality after Radiotherapy Treatment by Predicting Late Toxicities," 2022, published in Cancers
  • "Improving Biologics' Effectiveness in Clinical Oncology: From the Combination of Two Monoclonal Antibodies to Oligoclonal Antibody Mixtures," 2021, published in Cancers
  • "Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells," 2021, published in Scientific Reports
  • "Carcinoembryonic Antigen-Related Cell Adhesion Molecule Type 5 Receptor-Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer," 2023, published in JAMA Network Open

Collaborations play a significant role in their research activities. Frequent co-authors include:

  • Thierry Chardès
  • Françoise Cailler
  • Christel Larbouret
  • Véronique Garambois
  • Bérénice Framery

Best Publications

  • Cell-penetrating and cell-targeting peptides in drug delivery.

    Eric Vivès;Julien Schmidt;André Pèlegrin

  • Clinical radioimmunotherapy—the role of radiobiology

    Jean-Pierre Pouget;Isabelle Navarro-Teulon;Manuel Bardiès;Nicolas Chouin

  • Antibody-Indocyanin Conjugates for Immunophotodetection of Human Squamous Cell Carcinoma in Nude Mice

    S. Folli;P. Westermann;D. Braichotte;A. Pèlegrin

  • Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study.

    Leonora S F Boogerd;Charlotte E S Hoogstins;Dennis P Schaap;Miranda Kusters

  • Anti-HER2 vaccines: new prospects for breast cancer therapy

    Maha Zohra Ladjemi;William Jacot;Thierry Chardès;André Pèlegrin

  • Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy

    David Azria;Mahmut Ozsahin;Andrew Kramar;Sheila Peters

  • Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent.

    Charlotte E. S. Hoogstins;Leonora S. F. Boogerd;Babs G. Sibinga Mulder;J. Sven D. Mieog

  • The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy

    R Hudson;M Carcenac;K Smith;L Madden

  • Tumor-necrosis factor can enhance radio-antibody uptake in human colon carcinoma xenografts by increasing vascular permeability.

    S. Folli;A. Pelegrin;Y. Chalandon;Xiaofei Yao

  • In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas.

    Christel Larbouret;Bruno Robert;Isabelle Navarro-Teulon;Simon Thèzenas

  • Immunophotodiagnosis of colon carcinomas in patients injected with fluoresceinated chimeric antibodies against carcinoembryonic antigen.

    S Folli;G Wagnières;A Pèlegrin;J M Calmes

  • Concomitant use of tamoxifen with radiotherapy enhances subcutaneous breast fibrosis in hypersensitive patients.

    D Azria;S Gourgou;W J Sozzi;A Zouhair

  • Iodine-131-labeled MAb F(ab')2 fragments are more efficient and less toxic than intact anti-CEA antibodies in radioimmunotherapy of large human colon carcinoma grafted in nude mice

    Franz Buchegger;André Pèlegrin;Bernard Delaloye;Angelika Bischof-Delaloye

  • Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial.

    David Azria;Olivier Riou;Florence Castan;Tan Dat Nguyen

  • Cell Membrane is a More Sensitive Target than Cytoplasm to Dense Ionization Produced by Auger Electrons.

    Jean-Pierre Pouget;Jean-Pierre Pouget;Jean-Pierre Pouget;Lore Santoro;Laure Raymond;Nicolas Chouin

  • Antibody-fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice.

    André Pèlegrin;Silvio Folli;Franz Buchegger;Jean-Pierre Mach

  • Time-resolved Fluorescence Resonance Energy Transfer (TR-FRET) to Analyze the Disruption of EGFR/HER2 Dimers A NEW METHOD TO EVALUATE THE EFFICIENCY OF TARGETED THERAPY USING MONOCLONAL ANTIBODIES

    Nadège Gaborit;Christel Larbouret;Julie Vallaghe;Frédéric Peyrusson

  • In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptors' Down-regulation and Dimers' Disruption

    Christel Larbouret;Nadège Gaborit;Thierry Chardès;Mickaël Coelho

  • Single-Domain Antibody–Based and Linker-Free Bispecific Antibodies Targeting FcγRIII Induce Potent Antitumor Activity without Recruiting Regulatory T Cells

    Caroline Rozan;Amélie Cornillon;Corinne Pétiard;Martine Chartier

  • Cell Penetrating and Cell Targeting Peptides in Drug Delivery (revised version)

    Eric Vivès;Julien Schmidt;André Pèlegrin

Frequent Co-Authors

Jean-Pierre Mach
Jean-Pierre Mach University of Lausanne
Jean-Luc Teillaud
Jean-Luc Teillaud Grenoble Alpes University
Jacques Barbet
Jacques Barbet University of Nantes
Charles Theillet
Charles Theillet University of Montpellier
Hervé Bazin
Hervé Bazin Université Catholique de Louvain
Christoph Heusser
Christoph Heusser Novartis (Switzerland)
Jean-Marc Pascussi
Jean-Marc Pascussi University of Montpellier
Frédérique Penault-Llorca
Frédérique Penault-Llorca University of Clermont Auvergne
Jean Martinez
Jean Martinez University of Montpellier
Christophe Arnoult
Christophe Arnoult Grenoble Alpes University

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