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Medicine

D-Index
88
Citations
25197
World Ranking
13272
National Ranking
1236

Overview

Catharine M L West is affiliated with the University of Manchester in the United Kingdom. The research focuses primarily on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Their work spans several key subfields related to health and disease, including pulmonary and respiratory medicine, radiology, nuclear medicine and imaging, cancer research, radiation, and oncology.

West's research covers a range of main topics, notably cancer, hypoxia, and metabolism; advanced radiotherapy techniques; the effects of radiation exposure; and prostate cancer diagnosis and treatment. Additional topics include prostate cancer treatment and research, radiomics and machine learning applications in medical imaging, and studies related to head and neck cancer.

The scientist has contributed many publications to notable venues. These include Radiotherapy and Oncology, with 49 publications, the International Journal of Radiation Oncology*Biology*Physics featuring 15 papers, SSRN Electronic Journal with 7 works, bioRxiv (Cold Spring Harbor Laboratory) with 6, and Frontiers in Oncology with 5 publications.

Recent significant papers include:

  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk, 2020, Nature Communications
  • Hypofractionated radiotherapy in locally advanced bladder cancer: an individual patient data meta-analysis of the BC2001 and BCON trials, 2021, The Lancet Oncology
  • Predicting tumour radiosensitivity to deliver precision radiotherapy, 2022, Nature Reviews Clinical Oncology
  • Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan, 2020, Nature Communications
  • Polygenic hazard score is associated with prostate cancer in multi-ethnic populations, 2021, Nature Communications

Frequent coauthors working alongside West include Ananya Choudhury, Barry S. Rosenstein, D. Azria, Petra Seibold, and Ana Vega. These collaborations range widely and contribute to a strong presence in the fields of radiotherapy and oncology.

Best Publications

  • Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study.

    Gillian C. Barnett;Gillian C. Barnett;Charlotte E. Coles;Rebecca M. Elliott;Caroline Baynes

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix.

    Juliette A. Loncaster;Adrian L. Harris;Susan E. Davidson;John P. Logue

  • Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene.

    F. M. Buffa;A.L. Harris;C. M. West;Crispin Miller

  • Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix.

    R Airley;Juliette A Loncaster;Susan E Davidson;Michael Bromley

  • Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers.

    Stuart C Winter;Francesca M Buffa;Priyamal Silva;Crispin J Miller

  • Head and neck cancer—Part 1: Epidemiology, presentation, and prevention

    H Mehanna;V Paleri;C M L West;C Nutting

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • Imaging tumour hypoxia with positron emission tomography.

    Ian N Fleming;Roido Manavaki;Philip J Blower;Catharine West

  • The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis.

    H E Gee;F M Buffa;C Camps;A Ramachandran

  • GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

    Rachel E. Airley;Juliette Loncaster;James A. Raleigh;Adrian L. Harris

  • hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer

    Harriet E Gee;Carme Camps;Francesca M Buffa;Shalini Patiar

  • Tumour oxygenation levels correlate with dynamic contrast-enhanced magnetic resonance imaging parameters in carcinoma of the cervix.

    Rachel A Cooper;Bernadette M Carrington;Juliette A Loncaster;Susan M Todd

  • A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer

    Amanda Eustace;Navin Mani;Paul N. Span;Joely J. Irlam

  • ESTABLISHMENT OF A RADIOGENOMICS CONSORTIUM

    Catharine West;Barry S. Rosenstein

  • Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix.

    Catharine M L West;Susan E Davidson;Stephen A Roberts;Robin D Hunter

  • Targeting Hypoxia to Improve Non-Small Cell Lung Cancer Outcome.

    Ahmed Salem;Marie-Claude Asselin;Bart Reymen;Alan Jackson

  • The independence of intrinsic radiosensitivity as a prognostic factor for patient response to radiotherapy of carcinoma of the cervix

    Catharine M L West;Susan E Davidson;Stephen A Roberts;Robin D Hunter

  • Genetics and genomics of radiotherapy toxicity: towards prediction

    Catharine M L West;Gillian C Barnett

  • Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

    Jolyon H Hendry;Catharine M L West

Frequent Co-Authors

Alison M. Dunning
Alison M. Dunning University of Cambridge
David E. Neal
David E. Neal University of Cambridge
Peter Hoskin
Peter Hoskin University of Manchester
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Kenneth W. Muir
Kenneth W. Muir University of Manchester
Graham G. Giles
Graham G. Giles University of Melbourne
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Jyotsna Batra
Jyotsna Batra Queensland University of Technology
Johanna Schleutker
Johanna Schleutker Turku University Hospital
Alicja Wolk
Alicja Wolk Karolinska Institute

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