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Medicine

D-Index
78
Citations
25126
World Ranking
17953
National Ranking
752

Overview

Anthony Fyles is affiliated with the Princess Margaret Cancer Centre in Canada. Their research focuses primarily on cancer treatment, particularly involving gynecologic and breast cancers, with extensive work in oncology and radiotherapy.

Fyles's main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad areas, they have contributed to subfields such as Obstetrics and Gynecology, Cancer Research, Radiology, Nuclear Medicine and Imaging, Oncology, and Pathology and Forensic Medicine.

The scientist's main research topics encompass:

  • Endometrial and Cervical Cancer Treatments
  • Breast Cancer Treatment Studies
  • Cervical Cancer and HPV Research
  • Ovarian cancer diagnosis and treatment
  • Breast Lesions and Carcinomas
  • Advances in Oncology and Radiotherapy
  • Cancer Genomics and Diagnostics

Among notable recent papers authored by colleagues in the field and aligned with Fyles's research interests are:

  • Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy, 2020, Journal of Clinical Oncology
  • Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (OUTBACK): an international, open-label, randomised, phase 3 trial, 2023, The Lancet Oncology
  • Omitting Radiotherapy after Breast-Conserving Surgery in Luminal A Breast Cancer, 2023, New England Journal of Medicine
  • NRG Oncology/RTOG Consensus Guidelines for Delineation of Clinical Target Volume for Intensity Modulated Pelvic Radiation Therapy in Postoperative Treatment of Endometrial and Cervical Cancer: An Update, 2020, International Journal of Radiation Oncology*Biology*Physics
  • Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry, 2023, British Journal of Cancer

Frequent coauthors collaborating with Fyles include:

  • Jennifer Croke
  • Kathy Han
  • Michael Milosevic
  • Fei-Fei Liu
  • Linda Mileshkin

The scientist has contributed multiple publications to a range of academic venues, with the most frequent being:

  • Radiotherapy and Oncology
  • Journal of Clinical Oncology
  • International Journal of Radiation Oncology*Biology*Physics
  • Cancer Research
  • Advances in Radiation Oncology

Best Publications

  • Long-Term Results of Hypofractionated Radiation Therapy for Breast Cancer

    Timothy J Whelan;Jean-Philippe Pignol;Mark N Levine;Jim A Julian

  • Oxygenation predicts radiation response and survival in patients with cervix cancer

    Anthony W Fyles;Anthony W Fyles;Michael Milosevic;Michael Milosevic;Raimond Wong;Raimond Wong;Mary-Claire Kavanagh

  • Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer.

    Anthony W. Fyles;David R. McCready;Lee A. Manchul;Maureen E. Trudeau

  • Randomized Trial of Breast Irradiation Schedules After Lumpectomy for Women With Lymph Node-Negative Breast Cancer

    Timothy Whelan;Robert MacKenzie;Jim Julian;Mark Levine

  • Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma

    Ignace Vergote;Jos De Brabanter;Anthony Fyles;Kamma Bertelsen

  • Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy

    Jeffrey M. Arbeit;J. Martin Brown;K. S.Clifford Chao;J. Donald Chapman

  • Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial

    Stephanie M. de Boer;Melanie E. Powell;Linda Mileshkin;Dionyssios Katsaros

  • Trends in the Utilization of Brachytherapy in Cervical Cancer in the United States

    Kathy Han;Michael Milosevic;Anthony Fyles;Melania Pintilie

  • Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy

    Alicia León-Castillo;Stephanie M. de Boer;Melanie E. Powell;Linda R. Mileshkin

  • Tumor Hypoxia Has Independent Predictor Impact Only in Patients With Node-Negative Cervix Cancer

    A. Fyles;M. Milosevic;D. Hedley;M. Pintilie

  • Consensus Guidelines for Delineation of Clinical Target Volume for Intensity-Modulated Pelvic Radiotherapy for the Definitive Treatment of Cervix Cancer

    Karen Lim;William Small;Lorraine Portelance;Carien Creutzberg

  • The Effect of Treatment Duration in the Local Control of Cervix Cancer

    Anthony Fyles;Thomas J. Keane;Michael Barton;Janis Simm

  • Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial

    Stephanie M de Boer;Melanie E Powell;Linda Mileshkin;Dionyssios Katsaros

  • Interim Cosmetic and Toxicity Results From RAPID: A Randomized Trial of Accelerated Partial Breast Irradiation Using Three-Dimensional Conformal External Beam Radiation Therapy

    Ivo A. Olivotto;Timothy J. Whelan;Sameer Parpia;Do-Hoon Kim

  • External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial.

    Timothy J Whelan;Jim A Julian;Tanya S Berrang;Do-Hoon Kim

  • Interstitial Fluid Pressure Predicts Survival in Patients with Cervix Cancer Independent of Clinical Prognostic Factors and Tumor Oxygen Measurements

    Michael Milosevic;Anthony Fyles;David Hedley;Melania Pintilie

  • Diffusion-weighted MRI in cervical cancer

    Patrick Z. McVeigh;Aejaz M. Syed;Michael Milosevic;Anthony Fyles

  • MicroRNA-301 mediates proliferation and invasion in human breast cancer.

    Wei Shi;Kate Gerster;Nehad M. Alajez;Jasmine Tsang

  • Concurrent Cisplatin-based Chemotherapy plus Radiotherapy for Cervical Cancer–a Meta-analysis

    H. Lukka;H. Hirte;A. Fyles;G. Thomas

  • Inter- and intrafractional tumor and organ movement in patients with cervical cancer undergoing radiotherapy: a cinematic-MRI point-of-interest study.

    Philip Chan;Robert Dinniwell;Robert Dinniwell;Masoom A. Haider;Masoom A. Haider;Young Bin Cho;Young Bin Cho

Frequent Co-Authors

Michael Milosevic
Michael Milosevic Princess Margaret Cancer Centre
Melania Pintilie
Melania Pintilie Princess Margaret Cancer Centre
Richard P. Hill
Richard P. Hill Princess Margaret Cancer Centre
Fei-Fei Liu
Fei-Fei Liu Princess Margaret Cancer Centre
David A. Jaffray
David A. Jaffray The University of Texas MD Anderson Cancer Center
David W. Hedley
David W. Hedley Princess Margaret Cancer Centre
Carien L. Creutzberg
Carien L. Creutzberg Leiden University Medical Center
Amit M. Oza
Amit M. Oza Princess Margaret Cancer Centre
Timothy J. Whelan
Timothy J. Whelan McMaster University
Hans W. Nijman
Hans W. Nijman University Medical Center Groningen

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