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Medicine

D-Index
99
Citations
33609
World Ranking
8641
National Ranking
341

Overview

Otto C. Boerman is affiliated with Radboud University in the Netherlands and has contributed extensively to research in Medicine and Biochemistry, Genetics and Molecular Biology. Their scientific work has a focus on Oncology, Surgery, Radiology, Nuclear Medicine and Imaging, Cancer Research, and Molecular Biology.

The primary topics of Boerman's research include Cancer, Hypoxia, and Metabolism; Radiopharmaceutical Chemistry and Applications; Peptidase Inhibition and Analysis; Intraperitoneal and Appendiceal Malignancies; Enzyme function and inhibition; Cancer Research and Treatments; and Bone health and treatments.

Boerman has published in several academic venues, with multiple papers appearing in the European Journal of Nuclear Medicine and Molecular Imaging. Other publication venues include Scientific Reports, mAbs, Nature Communications, and Molecular Pharmaceutics.

Notable recent papers by Boerman include:

  • "Targeting of radioactive platinum-bisphosphonate anticancer drugs to bone of high metabolic activity," 2020, Scientific Reports
  • "Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy," 2021, mAbs
  • "Multimodal CEA-targeted fluorescence and radioguided cytoreductive surgery for peritoneal metastases of colorectal origin," 2022, Nature Communications
  • "Imaging angiogenesis in patients with head and neck squamous cell carcinomas by [68Ga]Ga-DOTA-E-[c(RGDfK)]2 PET/CT," 2020, European Journal of Nuclear Medicine and Molecular Imaging
  • "Novel VHH-Based Tracers with Variable Plasma Half-Lives for Imaging of CAIX-Expressing Hypoxic Tumor Cells," 2022, Molecular Pharmaceutics

Frequent collaborators in their research include:

  • Sandra Heskamp
  • Jan Marie de Gooyer
  • Fortuné M.K. Elekonawo
  • Mark Rijpkema
  • Johannes H.W. de Wilt

Best Publications

  • Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

    I Jolanda M de Vries;W Joost Lesterhuis;Jelle O Barentsz;Pauline Verdijk

  • Peritoneal Carcinomatosis of Colorectal Origin: Incidence and Current Treatment Strategies

    Manuel J. Koppe;Otto C. Boerman;Wim J. G. Oyen;Robert P. Bleichrodt

  • Accelerated Blood Clearance and Altered Biodistribution of Repeated Injections of Sterically Stabilized Liposomes

    Els T. M. Dams;Peter Laverman;Wim J. G. Oyen;Gert Storm

  • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

    I. Jolanda M. de Vries;Daniëlle J. E. B. Krooshoop;Nicole M. Scharenborg;W. Joost Lesterhuis

  • Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.

    Frank A. D. T. G. Wagener;Andreas Eggert;Otto C. Boerman;Wim J. G. Oyen

  • Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model.

    Marcel L Janssen;Wim J Oyen;Ingrid Dijkgraaf;Leon F Massuger

  • A Novel Method of 18F Radiolabeling for PET

    William J. McBride;Robert M. Sharkey;Habibe Karacay;Christopher A. D'Souza

  • Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

    Jurjen Tel;Erik H.J.G. Aarntzen;Tetsuro Baba;Gerty Schreibelt

  • Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity

    M H M G M den Brok;R P M Sutmuller;S Nierkens;E J Bennink

  • Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes

    Josbert M. Metselaar;Marca H. M. Wauben;Josee P. A. Wagenaar-Hilbers;Otto C. Boerman

  • Imaging of Inflammation by PET, Conventional Scintigraphy, and Other Imaging Techniques

    Martin Gotthardt;Chantal P. Bleeker-Rovers;Otto C. Boerman;Wim J.G. Oyen

  • Renal Toxicity of Radiolabeled Peptides and Antibody Fragments: Mechanisms, Impact on Radionuclide Therapy, and Strategies for Prevention

    Erik Vegt;Marion de Jong;Jack F.M. Wetzels;Rosalinde Masereeuw

  • Noninvasive Imaging of Tumor PD-L1 Expression Using Radiolabeled Anti–PD-L1 Antibodies

    Sandra Heskamp;Willemijn Hobo;Janneke D.M. Molkenboer-Kuenen;Daniel Olive

  • Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections.

    M.G. Netea;P.N.M. Demacker;B.J. Kullberg;O.C. Boerman

  • A novel facile method of labeling octreotide with (18)F-fluorine.

    Peter Laverman;William J. McBride;Robert M. Sharkey;Annemarie Eek

  • INTRAVENOUSLY ADMINISTERED SHORT INTERFERING RNA ACCUMULATES IN THE KIDNEY AND SELECTIVELY SUPPRESSES GENE FUNCTION IN RENAL PROXIMAL TUBULES

    Femke M. van de Water;Otto C. Boerman;Alfons C. Wouterse;Janny G. P. Peters

  • Improved targeting of the αvβ3 integrin by multimerisation of RGD peptides

    Ingrid Dijkgraaf;Ingrid Dijkgraaf;John A. W. Kruijtzer;Shuang Liu;Annemieke C. Soede

  • Comparison of a monomeric and dimeric radiolabeled RGD-peptide for tumor targeting.

    Marcel Janssen;Wim J.G. Oyen;Leon F.A.G. Massuger;Cathelijne Frielink

  • PSMA Ligands for Radionuclide Imaging and Therapy of Prostate Cancer: Clinical Status

    Susanne Lütje;Sandra Heskamp;Alexander S. Cornelissen;Thorsten D. Poeppel

  • Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy.

    Alexander B. Stillebroer;Peter F.A. Mulders;Otto C. Boerman;Wim J.G. Oyen

Frequent Co-Authors

Wim J.G. Oyen
Wim J.G. Oyen Humanitas University
David M. Goldenberg
David M. Goldenberg Immunomedics (United States)
Peter F.A. Mulders
Peter F.A. Mulders Radboud University
Robert M. Sharkey
Robert M. Sharkey University of Fukui
Marion de Jong
Marion de Jong Erasmus University Rotterdam
John A. Jansen
John A. Jansen Radboud University
Johan Bussink
Johan Bussink Radboud University
Gert Storm
Gert Storm Utrecht University
Leon F.A.G. Massuger
Leon F.A.G. Massuger Radboud University

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