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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
10880
World Ranking
11016
National Ranking
4761

Overview

Chien-Hsing Chang is affiliated with Northwestern University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these domains, their subfields of study include Molecular Biology, Immunology, Surgery, Oncology, and Radiology, Nuclear Medicine and Imaging.

Their work focuses on topics such as Cancer therapeutics and mechanisms, DNA Repair Mechanisms, Immunotherapy and Immune Responses, Bladder and Urothelial Cancer Treatments, Lung Cancer Research Studies, Monoclonal and Polyclonal Antibodies Research, and Glycosylation and Glycoproteins Research.

Chien-Hsing Chang has contributed to several research articles, including:

  • Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer, 2020, Oncotarget
  • Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas, 2024, Oncotarget
  • Abstract 5658: MG-Ig (molecularly grafted immunoglobulin): An alternative platform for production of bispecific antibodies, 2023, Cancer Research

The researcher regularly publishes in venues such as Oncotarget and Cancer Research. Frequent coauthors collaborating with Chang include Thomas M. Cardillo, Maria Zalath, Donglin Liu, Roberto Arrojo, and Robert M. Sharkey.

Best Publications

  • A Novel Method of 18F Radiolabeling for PET

    William J. McBride;Robert M. Sharkey;Habibe Karacay;Christopher A. D'Souza

  • Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting

    Edmund A. Rossi;David M. Goldenberg;Thomas M. Cardillo;William J. McBride

  • Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers.

    Thomas M. Cardillo;Serengulam V. Govindan;Robert M. Sharkey;Preeti Trisal

  • CD74: A New Candidate Target for the Immunotherapy of B-Cell Neoplasms

    Rhona Stein;M. Jules Mattes;Thomas M. Cardillo;Hans J. Hansen

  • Survival Improvement in Patients With Medullary Thyroid Carcinoma Who Undergo Pretargeted Anti–Carcinoembryonic-Antigen Radioimmunotherapy: A Collaborative Study With the French Endocrine Tumor Group

    Jean-François Chatal;Loïc Campion;Françoise Kraeber-Bodéré;Stephane Bardet

  • Multifunctional Antibodies by the Dock-and-Lock Method for Improved Cancer Imaging and Therapy by Pretargeting

    David M. Goldenberg;Edmund A. Rossi;Robert M. Sharkey;William J. McBride

  • Multivalent Immunoglobulin-Based Bioactive Assemblies

    Chien-Hsing Chang;David M. Goldenberg;Edmund A. Rossi

  • Improved 18F Labeling of Peptides with a Fluoride-Aluminum-Chelate Complex

    William J. McBride;Christopher A. D’Souza;Robert M. Sharkey;Habibe Karacay

  • Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.

    David M. Goldenberg;Edmund A. Rossi;Rhona Stein;Thomas M. Cardillo

  • Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody.

    Robert M Sharkey;Thomas M Cardillo;Edmund A Rossi;Chien-Hsing Chang

  • Molecular advances in pretargeting radioimunotherapy with bispecific antibodies.

    Chien-Hsing Chang;Robert M. Sharkey;Edmund A. Rossi;Habibe Karacay

  • Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab

    Edmund A. Rossi;David M. Goldenberg;Rosana Michel;Diane L. Rossi

  • Enhanced Delivery of SN-38 to Human Tumor Xenografts with an Anti-Trop-2–SN-38 Antibody Conjugate (Sacituzumab Govitecan)

    Robert M. Sharkey;William J. McBride;Thomas M. Cardillo;Serengulam V. Govindan

  • Combination therapy for inducing immune response to disease

    Chien-Hsing Chang;David M. Goldenberg;Edmund A. Rossi;Diane Rossi

  • The dock and lock method: a novel platform technology for building multivalent, multifunctional structures of defined composition with retained bioactivity.

    Chien-Hsing Chang;Edmund A. Rossi;David M. Goldenberg

  • Targeting, Toxicity, and Efficacy of 2-Step, Pretargeted Radioimmunotherapy Using a Chimeric Bispecific Antibody and 131I-Labeled Bivalent Hapten in a Phase I Optimization Clinical Trial

    Françoise Kraeber-Bodéré;Caroline Rousseau;Caroline Bodet-Milin;Ludovic Ferrer

  • Improving the Delivery of Radionuclides for Imaging and Therapy of Cancer Using Pretargeting Methods

    Robert M. Sharkey;Habibe Karacay;Thomas M. Cardillo;Chien-Hsing Chang

  • Bispecific antibodies for inducing apoptosis of tumor and diseased cells

    Chien-Hsing Chang;David M. Goldenberg;Hans J. Hansen;Eva Horak

  • Improved therapeutic results by pretargeted radioimmunotherapy of non-Hodgkin's lymphoma with a new recombinant, trivalent, anti-CD20, bispecific antibody.

    Robert M. Sharkey;Habibe Karacay;Samuel Litwin;Edmund A. Rossi

  • Bispecific Antibody Pretargeting PET (ImmunoPET) with an 124I-Labeled Hapten-Peptide

    William J McBride;Pat Zanzonico;Robert M Sharkey;Carl Norén

Frequent Co-Authors

David M. Goldenberg
David M. Goldenberg Immunomedics (United States)
Edmund A. Rossi
Edmund A. Rossi Immunomedics (United States)
Robert M. Sharkey
Robert M. Sharkey University of Fukui
Hans J. Hansen
Hans J. Hansen Eisai (Japan)
Wim J.G. Oyen
Wim J.G. Oyen Humanitas University
Ivan D. Horak
Ivan D. Horak Freie Universität Berlin
Pankaj Gupta
Pankaj Gupta Post Graduate Institute of Medical Education and Research
William H. McBride
William H. McBride University of California, Los Angeles
Otto C. Boerman
Otto C. Boerman Radboud University
Jacques Barbet
Jacques Barbet University of Nantes

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