Robin W. Carrell

Overview

Best Publications

• The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

  Gary A. Silverman;Phillip I. Bird;Robin W. Carrell;Frank C. Church

  1590
  Citations

• Structure of a serpin–protease complex shows inhibition by deformation

  James A. Huntington;Randy J. Read;Robin W. Carrell

  1411
  Citations

• The mechanism of Z alpha 1-antitrypsin accumulation in the liver.

  D A Lomas;D L Evans;J T Finch;R W Carrell

  1231
  Citations

• The anticoagulant activation of antithrombin by heparin.

  Lei Jin;Jan Pieter Abrahams;Jan Pieter Abrahams;Richard Skinner;Maurice Petitou

  892
  Citations

• Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder.

  Maurice C. Owen;Stephen O. Brennan;Jessica H. Lewis;Robin W. Carrell

  592
  Citations

• Crystal structure of uncleaved ovalbumin at 1.95 A resolution.

  Penelope E. Stein;Andrew G.W. Leslie;John T. Finch;Robin W. Carrell

  591
  Citations

• What do dysfunctional serpins tell us about molecular mobility and disease

  Penelope E. Stein;Robin W. Carrell

  587
  Citations

• α1-Antitrypsin and the serpins: variation and countervariation

  Robin Carrell;James Travis

  575
  Citations

• Crystal structure of ovalbumin as a model for the reactive centre of serpins.

  Penelope E. Stein;Andrew G. W. Leslie;John T. Finch;William G. Turnell

  558
  Citations

• Alpha1-antitrypsin deficiency--a model for conformational diseases.

  Robin W Carrell;David A Lomas

  554
  Citations

• Prevalence of antithrombin deficiency in the healthy population.

  R. C. Tait;Isobel D. Walker;D. J. Perry;S. I. A. M. Islam

  511
  Citations

• Biological implications of a 3 å structure of dimeric antithrombin

  Robin W Carrell;Penelope E Stein;Giulio Fermi;Mark R Wardell

  501
  Citations

• Hormone binding globulins undergo serpin conformational change in inflammation.

  P. A. Pemberton;P. E. Stein;M. B. Pepys;J. M. Potter

  465
  Citations

• Mobile reactive centre of serpins and the control of thrombosis.

  Robin W. Carrell;Dyfed Ll. Evans;Penelope E. Stein

  419
  Citations

• Familial dementia caused by polymerization of mutant neuroserpin

  Richard L. Davis;Antony E. Shrimpton;Peter D. Holohan;Charles Bradshaw

  415
  Citations

• How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration

  Aiwu Zhou;James A Huntington;Navraj S Pannu;Navraj S Pannu;Robin W Carrell

  332
  Citations

• Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin.

  David A. Lomas;Dyfed L. Evans;Stuart R. Stone;Wun Shaing W. Chang

  320
  Citations

• Serpinopathies and the conformational dementias

  David A. Lomas;Robin W. Carrell

  320
  Citations

• Inhibitory conformation of the reactive loop of alpha 1-antitrypsin.

  Peter R. Elliott;David A. Lomas;Robin W. Carrell;Jan Pieter Abrahams

  316
  Citations

• Alpha 1-antitrypsin Siiyama (Ser53-->Phe). Further evidence for intracellular loop-sheet polymerization.

  D A Lomas;J T Finch;K Seyama;T Nukiwa

  278
  Citations