World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
20033
World Ranking
17821
National Ranking
7294

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gary A. Silverman is affiliated with Washington University in St. Louis in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, cell biology, epidemiology, genetics, and aging as subfields.

Their recent publications include the following papers:

  • Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy, 2022, Nature Neuroscience
  • The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins: EVOLUTION, MECHANISM OF INHIBITION, NOVEL FUNCTIONS, AND A REVISED NOMENCLATURE, 2021, UNC Libraries
  • Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis, 2020, International Journal of Molecular Sciences
  • A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C, 2022, Proceedings of the National Academy of Sciences
  • SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation, 2022, Communications Biology

The main research topics that Gary A. Silverman has contributed to are:

  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • Genetics, Aging, and Longevity in Model Organisms
  • Genetics and Neurodevelopmental Disorders
  • Cellular transport and secretion
  • Cell death mechanisms and regulation
  • Endoplasmic Reticulum Stress and Disease

They frequently publish in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Communications Biology
  • Molecular Genetics and Metabolism
  • Nature Neuroscience
  • UNC Libraries

Frequent co-authors collaborating with Gary A. Silverman include:

  • Stephen C. Pak
  • Dustin Baldridge
  • Tim Schedl
  • Lindsay C. Burrage
  • Hieu D. Hoang

Gary A. Silverman was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

    Gary A. Silverman;Phillip I. Bird;Robin W. Carrell;Frank C. Church

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • An overview of the serpin superfamily

    Ruby H P Law;Qingwei Zhang;Sheena McGowan;Ashley Maurice Buckle

  • Isolation of single-copy human genes from a library of yeast artificial chromosome clones.

    Bernard H. Brownstein;Gary A. Silverman;Randall D. Little;David T. Burke

  • A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

    Sandra S. Schneider;Charlie Schick;Kimberlee E. Fish;Eric Miller

  • Cross-Class Inhibition of the Cysteine Proteinases Cathepsins K, L, and S by the Serpin Squamous Cell Carcinoma Antigen 1: A Kinetic Analysis†

    Charles Schick;Philip A. Pemberton;Guo-Ping Shi;Yoshiro Kamachi

  • Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product

    Peter H. Domer;Steven S. Fakharzadeh;Chein-Shing Chen;Jennifer Jockel

  • The DCC Gene: Structural Analysis and Mutations in Colorectal Carcinomas

    Kathleen R. Cho;Jonathan D. Oliner;Jonathan W. Simons;Lora Hedrick

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Squamous Cell Carcinoma Antigen 2 Is a Novel Serpin That Inhibits the Chymotrypsin-like Proteinases Cathepsin G and Mast Cell Chymase

    Charles Schick;Yoshiro Kamachi;Allison J. Bartuski;Sule Çataltepe

  • C. elegans in high-throughput drug discovery.

    Linda P. O'Reilly;Cliff J. Luke;David H. Perlmutter;Gary A. Silverman

  • Update of the human and mouse SERPIN gene superfamily.

    Claire Heit;Brian C Jackson;Monica McAndrews;Mathew W Wright

  • Immunolocalization of the Bcl-2 Protein Within Hematopoietic Neoplasms

    Mary Zutter;David Hockenbery;Gary A. Silverman;Stanley J. Korsmeyer

  • Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

    Gary A Silverman;James C Whisstock;D J Askew;Stephen C Pak

  • An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury

    Cliff J. Luke;Stephen C. Pak;Yuko S. Askew;Terra L. Naviglia

  • Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z.

    Sager J. Gosai;Joon Hyeok Kwak;Cliff J. Luke;Olivia S. Long

  • Human Macrophage Metalloelastase. GENOMIC ORGANIZATION, CHROMOSOMAL LOCATION, GENE LINKAGE, AND TISSUE-SPECIFIC EXPRESSION

    Azzaq Belaaouaj;J. M. Shipley;D. K. Kobayashi;D. B. Zimonjic

  • Co-expression of the Squamous Cell Carcinoma Antigens 1 and 2 in Normal Adult Human Tissues and Squamous Cell Carcinomas

    Sule Cataltepe;Eric R. Gornstein;Charles Schick;Yoshiro Kamachi

  • Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems.

    Gary A Silverman;James C Whisstock;Stephen Paul Bottomley;James A Huntington

Frequent Co-Authors

David H. Perlmutter
David H. Perlmutter Washington University in St. Louis
James C. Whisstock
James C. Whisstock Monash University
Dieter Brömme
Dieter Brömme University of British Columbia
Phillip I. Bird
Phillip I. Bird Monash University
Stanley J. Korsmeyer
Stanley J. Korsmeyer Harvard University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Stephen P. Bottomley
Stephen P. Bottomley Monash University
Ivet Bahar
Ivet Bahar University of Pittsburgh
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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