World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
37744
World Ranking
5189
National Ranking
2467

David H. Perlmutter publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David H. Perlmutter sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 184 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David H. Perlmutter D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David H. Perlmutter sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 75 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2018 - Fellow of the American Academy of Arts and Sciences

Overview

David H. Perlmutter is affiliated with Washington University in St. Louis in the United States. Their research spans the intersection of biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular and cell biology as well as epidemiology and neurology. Their work often addresses complex biological processes and disease mechanisms.

The scientist's primary fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields particularly emphasized in their research are:

  • Molecular Biology
  • Cell Biology
  • Epidemiology
  • Neurology
  • Electrical and Electronic Engineering

Research topics explored include:

  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • Ubiquitin and Proteasome Pathways
  • CRISPR and Genetic Engineering
  • Genetic Neurodegenerative Diseases
  • Neurological Disorders and Treatments

Recent papers published by David H. Perlmutter reflect a range of biomedical and computational research themes. These include:

  • "Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy" (2022, Nature Neuroscience)
  • "Detecting lithium plating dynamics in a solid-state battery with operando X-ray computed tomography using machine learning" (2023, npj Computational Materials)
  • "Variants in autophagy genes MTMR12 and FAM134A are putative modifiers of the hepatic phenotype in α1-antitrypsin deficiency" (2024, Hepatology)
  • "Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency" (2023, Hepatology Communications)
  • "A fluorescent reporter for rapid assessment of autophagic flux reveals unique autophagy signatures during C. elegans post-embryonic development and identifies compounds that modulate autophagy" (2024, Autophagy Reports)

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • npj Computational Materials
  • Hepatology
  • Autophagy Reports

David H. Perlmutter has collaborated most frequently with several coauthors:

  • Stephen C. Pak
  • Gary A. Silverman
  • Roland E. Dolle
  • Andrew S. Yoo
  • Daniela Ushizima

Recognition of their work includes the appointment as a Fellow of the American Academy of Arts and Sciences in 2018.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.

    D H Perlmutter;C A Dinarello;P I Punsal;H R Colten

  • An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis

    Tunda Hidvegi;Michael Ewing;Pamela Hale;Christine Dippold

  • Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.

    Jon A. J. Burrows;Lauren K. Willis;David H. Perlmutter

  • Functions of autophagy in normal and diseased liver

    Mark J. Czaja;Wen Xing Ding;Terrence M. Donohue;Scott L. Friedman

  • Biliary atresia: Current concepts and research directions. Summary of a symposium

    W F Balistreri;R Grand;J H Hoofnagle;F J Suchy

  • Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity

    Dongfeng Qu;Jeffrey H. Teckman;Satoshi Omura;David H. Perlmutter

  • A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency

    Ying Wu;Ina Whitman;Ernesto Molmenti;Kenneth Moore

  • Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung.

    D. L. Haviland;R. L. McCoy;W. T. Whitehead;H. Akama

  • Intracellular Inclusions Containing Mutant α1-Antitrypsin Z Are Propagated in the Absence of Autophagic Activity

    Takahiro Kamimoto;Shisako Shoji;Shisako Shoji;Shisako Shoji;Tunda Hidvegi;Noboru Mizushima;Noboru Mizushima;Noboru Mizushima

  • Chemical chaperones: a pharmacological strategy for disorders of protein folding and trafficking.

    David H Perlmutter

  • Evidence for an acute phase response in human intestinal epithelial cells.

    E.P. Molmenti;T. Ziambaras;D.H. Perlmutter

  • Retention of mutant α1-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response

    Jeffrey H. Teckman;David H. Perlmutter

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance

    Itender Singh;Abhay P. Sagare;Mireia Coma;David Perlmutter

  • Accumulation of Mutant α1-Antitrypsin Z in the Endoplasmic Reticulum Activates Caspases-4 and -12, NFκB, and BAP31 but Not the Unfolded Protein Response

    Tunda Hidvegi;Bela Z. Schmidt;Pamela Hale;David H. Perlmutter

  • Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes

    David H. Perlmutter;George I. Glover;Meheryar Rivetna;Charles S. Schasteen

Frequent Co-Authors

Gary A. Silverman
Gary A. Silverman Washington University in St. Louis
Harvey R. Colten
Harvey R. Colten Washington University in St. Louis
Evelina Gatti
Evelina Gatti Aix-Marseille University
Noboru Mizushima
Noboru Mizushima University of Tokyo
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Sergio Lavandero
Sergio Lavandero University of Chile
Ivet Bahar
Ivet Bahar University of Pittsburgh
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Donna B. Stolz
Donna B. Stolz University of Pittsburgh
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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