D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 72 Citations 34,817 166 World Ranking 3838 National Ranking 1955

Research.com Recognitions

Awards & Achievements

2018 - Fellow of the American Academy of Arts and Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

David H. Perlmutter mainly investigates Molecular biology, Cell biology, Autophagy, Alpha and Endoplasmic reticulum. His Cell biology research incorporates themes from Secretory protein and Mutant protein. His study looks at the intersection of Autophagy and topics like Cancer research with Immunology, Hepatic fibrosis and Liver injury.

David H. Perlmutter usually deals with Alpha and limits it to topics linked to Alpha 1-antitrypsin deficiency and Phenylbutyrate. His Endoplasmic reticulum study combines topics in areas such as Signal transduction, Mutant, Intracellular and Lactacystin. His research integrates issues of Programmed cell death and Physiology in his study of Autolysosome.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (1951 citations)

What are the main themes of his work throughout his whole career to date?

David H. Perlmutter mostly deals with Liver disease, Cell biology, Endoplasmic reticulum, Biochemistry and Alpha 1-antitrypsin deficiency. His studies deal with areas such as Fibrosis, Cirrhosis, Liver injury and Liver transplantation as well as Liver disease. His studies in Cell biology integrate themes in fields like Autophagy, Apoptosis, Fibroblast and Gene expression.

As part of the same scientific family, David H. Perlmutter usually focuses on Autophagy, concentrating on Hepatic fibrosis and intersecting with Carcinogenesis. The concepts of his Endoplasmic reticulum study are interwoven with issues in Proteostasis, Mutant protein, Mutant and Intracellular. His Alpha 1-antitrypsin deficiency study which covers Alpha that intersects with Phenotype.

He most often published in these fields:

  • Liver disease (26.78%)
  • Cell biology (23.50%)
  • Endoplasmic reticulum (24.04%)

What were the highlights of his more recent work (between 2011-2020)?

  • Cell biology (23.50%)
  • Alpha 1-antitrypsin deficiency (24.59%)
  • Liver disease (26.78%)

In recent papers he was focusing on the following fields of study:

David H. Perlmutter spends much of his time researching Cell biology, Alpha 1-antitrypsin deficiency, Liver disease, Autophagy and Immunology. His research in Cell biology intersects with topics in Mutant and Caenorhabditis elegans. David H. Perlmutter has researched Mutant in several fields, including Mutation and Molecular biology.

His Liver disease study combines topics from a wide range of disciplines, such as Liver transplantation, Transplantation, Heart transplantation, Cirrhosis and Pathology. His Autophagy research includes elements of Hepatocellular carcinoma, Cancer research, Programmed cell death and Hepatic fibrosis. His Endoplasmic reticulum research is multidisciplinary, relying on both Serpin and Intracellular.

Between 2011 and 2020, his most popular works were:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • Functions of autophagy in normal and diseased liver (286 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His scientific interests lie mostly in Immunology, Alpha 1-antitrypsin deficiency, Cell biology, Liver transplantation and Liver disease. His studies in Immunology integrate themes in fields like Cancer research, Liver injury, Hepatic fibrosis and Hepatocyte. His research in Alpha 1-antitrypsin deficiency intersects with topics in Endoplasmic reticulum and Intracellular.

His research links Mutant with Cell biology. David H. Perlmutter works mostly in the field of Liver transplantation, limiting it down to topics relating to Neutrophil elastase and, in certain cases, Cathepsin G, as a part of the same area of interest. David H. Perlmutter interconnects Genetics and Computational biology in the investigation of issues within Drug discovery.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

8302 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal.
Autophagy (2008)

2790 Citations

Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.

D H Perlmutter;C A Dinarello;P I Punsal;H R Colten.
Journal of Clinical Investigation (1986)

781 Citations

An Autophagy-Enhancing Drug Promotes Degradation of Mutant α1-Antitrypsin Z and Reduces Hepatic Fibrosis

Tunda Hidvegi;Michael Ewing;Pamela Hale;Christine Dippold.
Science (2010)

607 Citations

Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.

Jon A. J. Burrows;Lauren K. Willis;David H. Perlmutter.
Proceedings of the National Academy of Sciences of the United States of America (2000)

596 Citations

Biliary atresia: Current concepts and research directions. Summary of a symposium

W F Balistreri;R Grand;J H Hoofnagle;F J Suchy.
Hepatology (1996)

434 Citations

Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity

Dongfeng Qu;Jeffrey H. Teckman;Satoshi Omura;David H. Perlmutter.
Journal of Biological Chemistry (1996)

412 Citations

Functions of autophagy in normal and diseased liver

Mark J. Czaja;Wen Xing Ding;Terrence M. Donohue;Scott L. Friedman.
Autophagy (2013)

377 Citations

A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency

Ying Wu;Ina Whitman;Ernesto Molmenti;Kenneth Moore.
Proceedings of the National Academy of Sciences of the United States of America (1994)

375 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing David H. Perlmutter

Guido Kroemer

Guido Kroemer

Sorbonne University

Publications: 89

David A. Lomas

David A. Lomas

University College London

Publications: 87

Daniel J. Klionsky

Daniel J. Klionsky

University of Michigan–Ann Arbor

Publications: 60

Lorenzo Galluzzi

Lorenzo Galluzzi

Cornell University

Publications: 59

Oliver Kepp

Oliver Kepp

Institut Gustave Roussy

Publications: 57

Patrice Codogno

Patrice Codogno

Université Paris Cité

Publications: 55

Wen-Xing Ding

Wen-Xing Ding

University of Kansas

Publications: 43

Jeffrey L. Brodsky

Jeffrey L. Brodsky

University of Pittsburgh

Publications: 43

Ana Maria Cuervo

Ana Maria Cuervo

Albert Einstein College of Medicine

Publications: 42

Sergio Lavandero

Sergio Lavandero

University of Chile

Publications: 40

Saeid Ghavami

Saeid Ghavami

University of Manitoba

Publications: 40

Noboru Mizushima

Noboru Mizushima

University of Tokyo

Publications: 40

David C. Rubinsztein

David C. Rubinsztein

University of Cambridge

Publications: 40

Noel G. McElvaney

Noel G. McElvaney

Royal College of Surgeons in Ireland

Publications: 37

Maurizio Molinari

Maurizio Molinari

Universita della Svizzera Italiana

Publications: 35

Beth Levine

Beth Levine

The University of Texas Southwestern Medical Center

Publications: 35

Trending Scientists

Carlo Sansone

Carlo Sansone

University of Naples Federico II

Xiaohui Liang

Xiaohui Liang

University of Massachusetts Boston

Valerie A. Ramey

Valerie A. Ramey

University of California, San Diego

Jose M. Burdio

Jose M. Burdio

University of Zaragoza

Patrick Adlercreutz

Patrick Adlercreutz

Lund University

Lei Fu

Lei Fu

Wuhan University

Zhengguo Zhang

Zhengguo Zhang

South China University of Technology

Yuanzheng Yue

Yuanzheng Yue

Aalborg University

Markku Orell

Markku Orell

University of Oulu

Hans Kresse

Hans Kresse

University of Münster

Konrad A Hughen

Konrad A Hughen

Woods Hole Oceanographic Institution

Anthony P. Walker

Anthony P. Walker

Oak Ridge National Laboratory

Samuel B. Hutton

Samuel B. Hutton

University of Sussex

Mary A. Rutherford

Mary A. Rutherford

King's College London

Graeme I. Murray

Graeme I. Murray

University of Aberdeen

Vahé Petrosian

Vahé Petrosian

SLAC National Accelerator Laboratory

Something went wrong. Please try again later.