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Immunology
Ireland
2023

D-Index & Metrics

Medicine

D-Index
90
Citations
25034
World Ranking
12354
National Ranking
32

Research.com Recognitions

  • 2023 - Research.com Immunology in Ireland Leader Award
  • 2022 - Research.com Immunology in Ireland Leader Award

Overview

Noel G. McElvaney is affiliated with the Royal College of Surgeons in Ireland. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions in Pulmonary and Respiratory Medicine, Cancer Research, Oncology, Hematology, and Molecular Biology.

Their work addresses several key topics including Protease and Inhibitor Mechanisms, Peptidase Inhibition and Analysis, Cystic Fibrosis Research Advances, Blood Coagulation and Thrombosis Mechanisms, Neonatal Respiratory Health Research, Pulmonary Hypertension Research and Treatments, and Respiratory Support and Mechanisms.

Frequent publication venues for their research include:

  • American Journal of Respiratory and Critical Care Medicine
  • Journal of Cystic Fibrosis
  • Thorax
  • Journal of Hepatology
  • Zeitschrift für Gastroenterologie

Notable recent papers authored or co-authored by McElvaney are:

  • Characterization of the Inflammatory Response to Severe COVID-19 Illness (2020), American Journal of Respiratory and Critical Care Medicine
  • Alpha 1 -Antitrypsin Deficiency (2020), New England Journal of Medicine
  • Interleukin-6: obstacles to targeting a complex cytokine in critical illness (2021), The Lancet Respiratory Medicine
  • Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment (2022), Nature Microbiology
  • Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020) (2020), European Respiratory Review

McElvaney collaborates frequently with a number of co-authors, including Tomás P. Carroll, Oliver J. McElvaney, Mark P. Murphy, Cedric Gunaratnam, and Emer P. Reeves.

Best Publications

  • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.

    R. G. Crystal;N. G. Mcelvaney;N. G. Mcelvaney;M. A. Rosenfeld;Chin-Shyan Chu

  • Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.

    H Nakamura;K Yoshimura;N G McElvaney;R G Crystal

  • Characterization of the Inflammatory Response to Severe COVID-19 Illness.

    Oliver J. McElvaney;Natalie L. McEvoy;Oisín F. McElvaney;Tomás P. Carroll

  • Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

    Kenneth R Chapman;Jonathan G W Burdon;Eeva Piitulainen;Robert A Sandhaus

  • Systemic deficiency of glutathione in cystic fibrosis.

    J. H. Roum;R. Buhl;N. G. McElvaney;Z. Borok

  • Protease-antiprotease imbalance in the lungs of children with cystic fibrosis.

    P Birrer;N G McElvaney;A Rüdeberg;C W Sommer

  • Aerosol α1 -antitrypsin treatment for cystic fibrosis

    N.G. McElvaney;R.C. Hubbard;P. Birrer;R.G. Crystal

  • Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor.

    N G McElvaney;H Nakamura;P Birrer;C A Hébert

  • Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

    Terence R. Flotte;Bruce C. Trapnell;Margaret Humphries;Brenna Carey

  • Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

    Inna S. Afonina;Graham A. Tynan;Susan E. Logue;Sean P. Cullen

  • α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.

    David A. Bergin;Emer P. Reeves;Paula Meleady;Michael Henry

  • European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency.

    Marc Miravitlles;Asger Dirksen;Ilaria Ferrarotti;Vladimir Koblizek

  • Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding

    Clifford C. Taggart;Sally Ann Cryan;Sinead Weldon;Aileen Gibbons

  • TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.

    Catherine M. Greene;Tomás P. Carroll;Stephen G. J. Smith;Clifford C. Taggart

  • Association of IL-10 polymorphism with severity of illness in community acquired pneumonia

    P M Gallagher;G Lowe;T Fitzgerald;A Bella

  • Neutrophil elastase up‐regulates interleukin‐8 via toll‐like receptor 4

    James M Devaney;Catherine M Greene;Clifford C Taggart;Tomás P Carroll

  • α1-Antitrypsin deficiency

    Catherine M. Greene;Stefan J. Marciniak;Jeffrey Teckman;Ilaria Ferrarotti

  • Inactivation of Human β-Defensins 2 and 3 by Elastolytic Cathepsins

    Clifford C. Taggart;Catherine M. Greene;Stephen G. Smith;Rodney L. Levine

  • A Preliminary Study of Aerosolized Recombinant Human Deoxyribonuclease I in the Treatment of Cystic Fibrosis

    Richard C. Hubbard;Noel G. McElvaney;Peter Birrer;Steven Shak

  • Sputum Candida albicans Presages FEV1 Decline and Hospital-Treated Exacerbations in Cystic Fibrosis

    Sanjay H. Chotirmall;Elaine O'Donoghue;Kathleen Bennett;Cedric Gunaratnam

Frequent Co-Authors

Catherine M. Greene
Catherine M. Greene Royal College of Surgeons in Ireland
Clifford C. Taggart
Clifford C. Taggart Queen's University Belfast
Ronald G. Crystal
Ronald G. Crystal Cornell University
Kenneth R. Chapman
Kenneth R. Chapman University of Toronto
James K. Stoller
James K. Stoller Cleveland Clinic
David A. Lomas
David A. Lomas University College London
Marc Miravitlles
Marc Miravitlles Vall d'Hebron Hospital Universitari
Martin Clynes
Martin Clynes Dublin City University
Michael M. Tunney
Michael M. Tunney Queen's University Belfast
Kevin Kavanagh
Kevin Kavanagh National University of Ireland, Maynooth

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