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Jean-Michel Sallenave

Jean-Michel Sallenave

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
8818
World Ranking
14088
National Ranking
540

Overview

Jean-Michel Sallenave is affiliated with Université Paris Cité in France. Their research primarily focuses on medicine and the intersecting fields of immunology and microbiology, with a specialization in pulmonary and respiratory medicine. The scientist's body of work spans several key subfields including immunology, epidemiology, infectious diseases, and health, toxicology, and mutagenesis.

The research topics addressed by Jean-Michel Sallenave cover a range of areas within respiratory health and immune system interactions. These topics include neonatal respiratory health research, cystic fibrosis research advances, respiratory support and mechanisms, respiratory viral infections research, immune cells in cancer, immune response and inflammation, and immune cell function and interaction.

The scientist has contributed to several publications, notably in the following venues:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Environmental Pollution
  • Journal of Cystic Fibrosis
  • Biomaterials

Some recent papers reflecting the scope of their work include:

  • Innate Immune Signaling and Proteolytic Pathways in the Resolution or Exacerbation of SARS-CoV-2 in Covid-19: Key Therapeutic Targets? (2020) Frontiers in Immunology
  • Influenza A Virus Pre-Infection Exacerbates Pseudomonas aeruginosa-Mediated Lung Damage Through Increased MMP-9 Expression, Decreased Elafin Production and Tissue Resilience (2020) Frontiers in Immunology
  • Pulmonary delivery of silver nanoparticles prevents influenza infection by recruiting and activating lymphoid cells (2024) Biomaterials
  • To Vaccinate or not: Influenza Virus and Lung Cancer Progression (2021) Trends in cancer
  • IL-6-elafin genetically modified macrophages as a lung immunotherapeutic strategy against Pseudomonas aeruginosa infections (2021) Molecular Therapy

Jean-Michel Sallenave frequently collaborates with a consistent group of coauthors, including Bérengère Villeret, Ignacio García-Verdugo, Lydie Martín-Faivre, Saadé Kheir, and Maëlys Born-Bony. These collaborations indicate established research partnerships within related scientific areas.

Best Publications

  • Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

    Ai Ing Lim;Ai Ing Lim;Ai Ing Lim;Yan Li;Yan Li;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Ralph Stadhouders

  • Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.

    Jean-Michel Sallenave;Jerry Shulmann;John Crossley;Manel Jordana

  • SLPI and elafin: one glove, many fingers.

    Steven E. Williams;Thomas I. Brown;Ali Roghanian;Jean-Michel Sallenave

  • Expression of natural antimicrobials by human placenta and fetal membranes.

    A.E. King;A. Paltoo;R.W. Kelly;J.-M. Sallenave

  • Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis

    Jean-Paul Motta;Luis G. Bermúdez-Humarán;Céline Deraison;Céline Deraison;Céline Deraison;Laurence Martin;Laurence Martin;Laurence Martin

  • Elafin (elastase-specific inhibitor) has anti-microbial activity against gram-positive and gram-negative respiratory pathogens.

    A.J. Simpson;A.I. Maxwell;J.R.W. Govan;C. Haslett

  • Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs

    Camille Ehre;Erin N. Worthington;Rachael M. Liesman;Barbara R. Grubb

  • The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease

    Jean-Michel Sallenave

  • Adenoviral Gene Delivery of Elafin and Secretory Leukocyte Protease Inhibitor Attenuates NF-κB-Dependent Inflammatory Responses of Human Endothelial Cells and Macrophages to Atherogenic Stimuli

    Peter A. Henriksen;Peter A. Henriksen;Mary Hitt;Zhou Xing;Jun Wang

  • Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils.

    Jean-Michel Sallenave;Mustapha Si-Ta har;Gerard Cox;Michel Chignard

  • IL-33 Enhances Lipopolysaccharide-Induced Inflammatory Cytokine Production from Mouse Macrophages by Regulating Lipopolysaccharide Receptor Complex

    Quentin Espinassous;Elvira Garcia-de-Paco;Ignacio Garcia-Verdugo;Monique Synguelakis

  • Antimicrobial activity of antiproteinases.

    J.-M. Sallenave

  • Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.

    Jean-Michel Sallenave

  • Diagnostic importance of pulmonary interleukin-1β and interleukin-8 in ventilator-associated pneumonia

    Andrew Conway Morris;Kallirroi Kefala;Thomas S Wilkinson;Olga Lucia Moncayo-Nieto

  • Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia.

    Mathilde Delaval;Sonja Boland;Brigitte Solhonne;Brigitte Solhonne;Marie-Anne Nicola

  • Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.

    Jean–Paul Motta;Jean–Paul Motta;Jean–Paul Motta;Laurent Magne;Laurent Magne;Delphyne Descamps;Delphyne Descamps;Corinne Rolland;Corinne Rolland;Corinne Rolland

  • Innate Immune Defences in the Human Uterus during Pregnancy

    A.E. King;R.W. Kelly;J.-M. Sallenave;A.D. Bocking

  • Intranasal Mucosal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances the Protection of BCG-Primed Guinea Pigs against Pulmonary Tuberculosis

    Zhou Xing;Christine T. McFarland;Jean-Michel Sallenave;Angelo Izzo

  • C5a mediates peripheral blood neutrophil dysfunction in critically ill patients

    Andrew Conway Morris;Kallirroi Kefala;Thomas S. Wilkinson;Kevin Dhaliwal

  • Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway.

    Viviane Balloy;Viviane Balloy;Jean-Michel Sallenave;Jean-Michel Sallenave;Yongzheng Wu;Yongzheng Wu;Lhousseine Touqui;Lhousseine Touqui

Frequent Co-Authors

Michel Chignard
Michel Chignard Institut Pasteur
Viviane Balloy
Viviane Balloy Sorbonne University
Christopher Haslett
Christopher Haslett University of Edinburgh
Jack Gauldie
Jack Gauldie McMaster University
Zhou Xing
Zhou Xing McMaster University
Mustapha Si-Tahar
Mustapha Si-Tahar François Rabelais University
Aleksander Edelman
Aleksander Edelman Université Paris Cité
Philippe Langella
Philippe Langella University of Paris-Saclay
Luis G. Bermúdez-Humarán
Luis G. Bermúdez-Humarán University of Paris-Saclay

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