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Immunology

D-Index
112
Citations
38310
World Ranking
461
National Ranking
17

Medicine

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113
Citations
38655
World Ranking
5016
National Ranking
192

Overview

Pieter S. Hiemstra is affiliated with Leiden University Medical Center in the Netherlands, concentrating their research within the field of Medicine, particularly Pulmonary and Respiratory Medicine, Infectious Diseases, Molecular Biology, Immunology, and Epidemiology.

Their work spans multiple significant topics including Chronic Obstructive Pulmonary Disease (COPD) Research, Neonatal Respiratory Health Research, SARS-CoV-2 and COVID-19 Research, Asthma and respiratory diseases, COVID-19 Clinical Research Studies, IL-33, ST2, and ILC Pathways, as well as Pediatric health and respiratory diseases.

Hiemstra has contributed to various academic outlets, with frequent publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • European Respiratory Journal
  • Respiratory Research
  • Thorax

Among the recent papers authored or co-authored by Pieter S. Hiemstra are:

  • "An emerging class of air pollutants: Potential effects of microplastics to respiratory human health?", 2020, The Science of The Total Environment
  • "Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD", 2022, European Respiratory Review
  • "Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19", 2021, Nature Immunology
  • "Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle", 2020, Antimicrobial Agents and Chemotherapy
  • "Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients", 2020, Cancer Immunology Immunotherapy

Pieter S. Hiemstra frequently collaborates with a core group of researchers including:

  • Anne M. van der Does
  • Dennis K. Ninaber
  • Alen Faiz
  • Wim Timens
  • Maarten van den Berge

Best Publications

  • Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3.

    Ole E. Sørensen;Per Follin;Anders H. Johnsen;Jero Calafat

  • An angiogenic role for the human peptide antibiotic LL-37/hCAP-18

    Rembert Koczulla;Georges von Degenfeld;Christian Kupatt;Florian Krötz

  • Innate immunity in the lung: how epithelial cells fight against respiratory pathogens

    R Bals;P S Hiemstra

  • In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation.

    Tim G. A. M. Wolfs;Wim A. Buurman;Annemarie van Schadewijk;Bart de Vries

  • The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor

    G. Sandra Tjabringa;Jamil Aarbiou;Dennis K. Ninaber;Jan Wouter Drijfhout

  • 4-Hydroxy-2-Nonenal, a Specific Lipid Peroxidation Product, Is Elevated in Lungs of Patients with Chronic Obstructive Pulmonary Disease

    Irfan Rahman;Annemarie A. M. van Schadewijk;Ann J. L. Crowther;Pieter S. Hiemstra

  • Antibacterial activity of antileukoprotease.

    P S Hiemstra;R J Maassen;J Stolk;R Heinzel-Wieland

  • Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.

    Jimmy F. P. Berbée;Mariëtte R Boon;P. Padmini S. J. Khedoe;Alexander Bartelt

  • The innate immune function of airway epithelial cells in inflammatory lung disease

    Pieter S. Hiemstra;Paul B. McCray;Robert Bals

  • Transforming Growth Factor β1 and Recruitment of Macrophages and Mast Cells in Airways in Chronic Obstructive Pulmonary Disease

    W. I. De Boer;A. Van Schadewijk;J. K. Sont;H. S. Sharma

  • Monocyte chemoattractant protein 1, interleukin 8, and chronic airways inflammation in COPD.

    Willem I. de Boer;Jacob K. Sont;Annemarie van Schadewijk;Jan Stolk

  • An emerging class of air pollutants: Potential effects of microplastics to respiratory human health?

    Luís Fernando Amato-Lourenço;Luciana dos Santos Galvão;Letty A. de Weger;Pieter S. Hiemstra

  • Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD.

    Diana C Grootendorst;Stefanie A Gauw;Renate M Verhoosel;Peter J Sterk

  • Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells.

    Louise A Duits;Bep Ravensbergen;Mirjam Rademaker;Pieter S Hiemstra

  • Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.

    Stephanie A. Christenson;Katrina Steiling;Maarten van den Berge;Kahkeshan Hijazi

  • High Expression Levels of Keratinocyte Antimicrobial Proteins in Psoriasis Compared with Atopic Dermatitis

    Gys J. de Jongh;Patrick L.J.M. Zeeuwen;Martina Kucharekova;Rolph Pfundt

  • Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure

    Mahyar Aghapour;Pourya Raee;Seyed Javad Moghaddam;Pieter S. Hiemstra

  • IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha.

    J. A. M. Langermans;M. E. B. Van Der Hulst;P. H. Nibbering;P. S. Hiemstra

  • Human Cathelicidin LL-37 Is a Chemoattractant for Eosinophils and Neutrophils That Acts via Formyl-Peptide Receptors

    G. Sandra Tjabringa;Dennis K. Ninaber;Jan Wouter Drijfhout;Klaus F. Rabe

  • Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation

    F. Luppi;F. Luppi;A.M. Longo;W.I. de Boer;K.F. Rabe

Frequent Co-Authors

Wim Timens
Wim Timens University Medical Center Groningen
Klaus F. Rabe
Klaus F. Rabe Kiel University
Peter J. Sterk
Peter J. Sterk University of Amsterdam
Dirkje S. Postma
Dirkje S. Postma University Medical Center Groningen
Hermelijn H. Smits
Hermelijn H. Smits Leiden University Medical Center
Reinoud Gosens
Reinoud Gosens University of Groningen
Huib A. M. Kerstjens
Huib A. M. Kerstjens University Medical Center Groningen
Per Bakke
Per Bakke University of Bergen
L. A. Van Es
L. A. Van Es Leiden University
Peter H. Nibbering
Peter H. Nibbering Leiden University Medical Center

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