World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
56
Citations
11187
World Ranking
3724
National Ranking
139

Overview

Hermelijn H. Smits is affiliated with Leiden University Medical Center in the Netherlands. Their research spans multiple disciplines within medicine, with a focus on immunology, infectious diseases, parasitology, and epidemiology. The scientist's work addresses key topics including parasites and host interactions, pediatric health and respiratory diseases, SARS-CoV-2 and COVID-19 research, extracellular vesicles in disease, and asthma and respiratory diseases.

Smits has contributed to 57 publications in the field of medicine and 32 specifically in immunology and microbiology. Their subfield expertise includes immunology with 18 publications, infectious diseases with 15 publications, parasitology with 14, epidemiology with 10, and emergency medical services with 7. Key subjects covered in their work highlight the interface of parasitic biology and host immune responses as well as clinical and immunological aspects of respiratory conditions and viral infections like COVID-19.

Their recent notable papers include:

  • Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention, 2020, The Lancet
  • Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19, 2021, Nature Immunology
  • DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells, 2020, Journal of Extracellular Vesicles
  • Immunological factors linked to geographical variation in vaccine responses, 2023, Nature Reviews Immunology
  • Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility, 2023, Journal of Extracellular Vesicles

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Allergy, Nature Immunology, and Journal of Extracellular Vesicles. They have collaborated extensively with several researchers, including Maria Yazdanbakhsh, Simon P. Jochems, Cornelis H. Hokke, Pieter S. Hiemstra, and Tamar Tak.

Best Publications

  • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.

    Hermelijn H Smits;Anneke Engering;Desiree van der Kleij;Esther C de Jong

  • Dendritic cell-mediated T cell polarization.

    Esther C. de Jong;Hermelijn H. Smits;Hermelijn H. Smits;Martien L. Kapsenberg

  • Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

    Mathijs P. Bergman;Anneke Engering;Hermelijn H. Smits;Sandra J. van Vliet

  • Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.

    Bart Everts;Georgia Perona-Wright;Hermelijn H. Smits;Cornelis H. Hokke

  • Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules.

    Rick M. Maizels;Hermelijn H. Smits;Henry J. McSorley

  • Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

    Bart Everts;Leonie Hussaarts;Nicole N. Driessen;Moniek H.J. Meevissen

  • Sustained IL-12 signaling is required for Th1 development.

    Veronica Athie-Morales;Hermelijn H. Smits;Doreen A. Cantrell;Catharien M. U. Hilkens

  • Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin‐8 in nasal lavage in asthmatic subjects in vivo

    K. Grünberg;M. C. Timmers;H. H. Smits;E. P. A. de Klerk

  • Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.

    K. Grünberg;H. H. Smits;M. C. Timmers;E. P. A. De Klerk

  • Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development.

    Hermelijn H Smits;Astrid J van Beelen;Christina Hessle;Robert Westland

  • Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses.

    Alice H. Costain;Alice H. Costain;Andrew S. MacDonald;Hermelijn H. Smits

  • Chronic Helminth Infections Protect Against Allergic Diseases by Active Regulatory Processes

    Hermelijn H. Smits;Bart Everts;Franca C. Hartgers;Maria Yazdanbakhsh

  • Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention

    Erika von Mutius;Hermelijn H Smits

  • Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.

    Luciën E. P. M. van der Vlugt;Lucja A. Labuda;Arifa Ozir-Fazalalikhan;Ellen Lievers

  • Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection

    Hermelijn H. Smits;Hermelijn H. Smits;Hamida Hammad;Menno van Nimwegen;Thomas Soullie

  • IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut.

    Susanne Sattler;Guang-Sheng Ling;Damo Xu;Leonie Hussaarts

  • IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.

    P. Kaliński;H. H. Smits;J. H. Schuitemaker;P. L. Vieira

  • Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum

    Linda J. Wammes;Firdaus Hamid;Aprilianto E. Wiria;Brechje de Gier

  • Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma

    J.C.C.M. in 't Veen;H.W.F.M. de Gouw;H.H. Smits;J.K. Sont

  • Regulatory B-cell induction by helminths: implications for allergic disease.

    Leonie Hussaarts;Luciën E.P.M. van der Vlugt;Maria Yazdanbakhsh;Hermelijn H. Smits

Frequent Co-Authors

Maria Yazdanbakhsh
Maria Yazdanbakhsh Leiden University Medical Center
Pieter S. Hiemstra
Pieter S. Hiemstra Leiden University Medical Center
Eddy A. Wierenga
Eddy A. Wierenga University of Amsterdam
Ayola A. Adegnika
Ayola A. Adegnika University of Tübingen
Peter G. Kremsner
Peter G. Kremsner University of Tübingen
Cornelis H. Hokke
Cornelis H. Hokke Leiden University Medical Center
Martien L. Kapsenberg
Martien L. Kapsenberg University of Amsterdam
Esther C. de Jong
Esther C. de Jong University of Amsterdam
Nikolaos G. Papadopoulos
Nikolaos G. Papadopoulos National and Kapodistrian University of Athens
Gunilla Hedlin
Gunilla Hedlin Karolinska Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Immunology in the USA can open doors to various healthcare career paths, many of which are accessible through online programs. For those interested in entering nursing without prior experience, exploring online adn programs for non nurses is a great starting point. These programs offer a flexible route for newcomers to develop essential clinical skills.

If you're looking to advance quickly, 12-month accelerated nursing programs provide an intensive pathway to a Bachelor of Science in Nursing. Such programs are ideal for students eager to enter the workforce faster while building a strong foundation in health sciences.

For those seeking a faster entry into nursing with less rigorous admission criteria, easy admission lpn programs offer practical training for Licensed Practical Nurses, serving as a valuable stepping stone within the healthcare field.

Finally, advancing to become a Nurse Practitioner is possible through various programs, among which easiest np program options focus on providing streamlined entry with balanced academic rigor. These pathways support professionals looking to deepen their expertise and clinical responsibilities.

Best Scientists Citing Hermelijn H. Smits

Trending Scientists