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Immunology

D-Index
104
Citations
36660
World Ranking
620
National Ranking
22

Research.com Recognitions

  • 2019 - Spinoza Prize, Dutch Research Council
  • 2017 - Royal Netherlands Academy of Arts and Sciences

Overview

Yvette van Kooyk is affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their research primarily focuses on immunology, molecular biology, and oncology, with significant contributions in the intersection of these fields.

The main fields of study covered by their work include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their research spans several specialized subfields such as:

  • Immunology
  • Molecular Biology
  • Oncology
  • Microbiology
  • Radiology, Nuclear Medicine and Imaging

Key research topics addressed in their publications are:

  • Immunotherapy and Immune Responses
  • Glycosylation and Glycoproteins Research
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • RNA Interference and Gene Delivery
  • T-cell and B-cell Immunology
  • Galectins and Cancer Biology

Yvette van Kooyk has contributed to multiple research papers, including notable recent works such as:

  • The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes, 2020, Cancer Cell
  • Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9, 2021, Nature Communications
  • Glioblastomas exploit truncated O - linked glycans for local and distant immune modulation via the macrophage galactose-type lectin, 2020, Proceedings of the National Academy of Sciences
  • Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models, 2020, ACS Central Science
  • Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota, 2020, bioRxiv (Cold Spring Harbor Laboratory)

The frequent publication venues for their work include:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • Communications Biology
  • Proceedings of the National Academy of Sciences

Collaboration features prominently in their research, with frequent coauthors including:

  • Sandra J. van Vliet
  • Ernesto Rodríguez
  • Hakan Kalay
  • Fabrizio Chiodo
  • Juan J. García-Vallejo

Recognition for their scientific work includes receiving the Spinoza Prize from the Dutch Research Council in 2019 and being elected to the Royal Netherlands Academy of Arts and Sciences in 2017.

Best Publications

  • Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function

    Teunis B.H. Geijtenbeek;Sandra J. van Vliet;Estella A. Koppel;Marta Sanchez-Hernandez

  • DC-SIGN: escape mechanism for pathogens

    Yvette van Kooyk;Teunis B H Geijtenbeek

  • C-type lectin receptors on dendritic cells and langerhans cells

    Carl G Figdor;Yvette van Kooyk;Gosse J Adema

  • Protein-glycan interactions in the control of innate and adaptive immune responses

    Yvette Van Kooyk;Gabriel Adrián Rabinovich

  • The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.

    Anneke Engering;Teunis B. H. Geijtenbeek;Sandra J. van Vliet;Mietske Wijers

  • C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB

    Sonja I. Gringhuis;Jeroen den Dunnen;Manja Litjens;Bert van het Hof

  • Langerin is a natural barrier to HIV-1 transmission by Langerhans cells.

    Lot de Witte;Alexey Nabatov;Marjorie Pion;Donna Fluitsma

  • SELF- AND NONSELF-RECOGNITION BY C-TYPE LECTINS ON DENDRITIC CELLS

    Teunis B H Geijtenbeek;Sandra J van Vliet;Anneke Engering;Bert A 't Hart

  • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.

    Hermelijn H Smits;Anneke Engering;Desiree van der Kleij;Esther C de Jong

  • S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

    Sergey R. Konstantinov;Hauke Smidt;Willem M. de Vos;Willem M. de Vos;Sven C. M. Bruijns

  • The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

    Floris Dammeijer;Mandy van Gulijk;Evalyn E. Mulder;Melanie Lukkes

  • Cutting Edge: Carbohydrate Profiling Identifies New Pathogens That Interact with Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin on Dendritic Cells

    Ben J. Appelmelk;Irma van Die;Sandra J. van Vliet;Christina M. J. E. Vandenbroucke-Grauls

  • Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN

    Klaas P.J.M. van Gisbergen;Marta Sanchez-Hernandez;Teunis B.H. Geijtenbeek;Yvette van Kooyk

  • Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions

    Valentin Grabovsky;Sara Feigelson;Chun Chen;Diederik A. Bleijs

  • The tumour glyco-code as a novel immune checkpoint for immunotherapy.

    Ernesto RodrÍguez;Sjoerd T T Schetters;Yvette van Kooyk

  • The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

    Irma van Die;Sandra J van Vliet;A Kwame Nyame;Richard D Cummings

  • Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.

    Mathijs P. Bergman;Anneke Engering;Hermelijn H. Smits;Sandra J. van Vliet

  • A Dendritic Cell–Specific Intercellular Adhesion Molecule 3–Grabbing Nonintegrin (Dc-Sign)–Related Protein Is Highly Expressed on Human Liver Sinusoidal Endothelial Cells and Promotes HIV-1 Infection

    Arman A Bashirova;Teunis B.H. Geijtenbeek;Gerard C.F. van Duijnhoven;Sandra J. van Vliet

  • Neuroinflammation: Microglia and T Cells Get Ready to Tango.

    Sjoerd T. T. Schetters;Diego Gomez-Nicola;Juan J. Garcia-Vallejo;Yvette Van Kooyk

  • Ins and outs of LFA-1

    M. Lub;Y. van Kooyk;C.G. Figdor

  • Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy.

    Ulrike Kämmerer;Andreas O. Eggert;Michaela Kapp;Alexander D. McLellan

Frequent Co-Authors

Juan J. Garcia-Vallejo
Juan J. Garcia-Vallejo University of Amsterdam
Sandra J. van Vliet
Sandra J. van Vliet University of Amsterdam
Tanja D. de Gruijl
Tanja D. de Gruijl Vrije Universiteit Amsterdam
Carl G. Figdor
Carl G. Figdor Radboud University
Irma van Die
Irma van Die VU University Medical Center
Ben J. Appelmelk
Ben J. Appelmelk Amsterdam University Medical Centers
Johan Garssen
Johan Garssen Utrecht University
Gabriel A. Rabinovich
Gabriel A. Rabinovich Experimental Medicine and Biology Institute
Gert Storm
Gert Storm Utrecht University
Bert A. 't Hart
Bert A. 't Hart University of Amsterdam

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