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Bruno G. De Geest

Bruno G. De Geest

D-Index & Metrics

Materials Science

D-Index
64
Citations
13969
World Ranking
5930
National Ranking
59

Chemistry

D-Index
62
Citations
12748
World Ranking
8896
National Ranking
113

Overview

Bruno G. De Geest is affiliated with Ghent University in Belgium and focuses on research intersecting immunology, molecular biology, and biomedical engineering. Their work spans multiple disciplines including immunology and microbiology, biochemistry, genetics, molecular biology, and medicine.

The scientist's research encompasses various subfields such as immunology, molecular biology, organic chemistry, biomedical engineering, and biomaterials. Central topics in their work include immunotherapy and immune responses, RNA interference and gene delivery, immune response and inflammation, nanoplatforms for cancer theranostics, monoclonal and polyclonal antibodies research, advanced polymer synthesis and characterization, and SARS-CoV-2 and COVID-19 research.

Bruno G. De Geest has published in a range of scientific venues, with frequent publications appearing in:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Journal of the American Chemical Society
  • Advanced Healthcare Materials
  • Biomacromolecules

Recent publications include:

  • The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera (2021, bioRxiv [Cold Spring Harbor Laboratory])
  • Engineering Strategies for Lymph Node Targeted Immune Activation (2020, Accounts of Chemical Research)
  • From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer (2021, Advanced Materials)
  • Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles (2020, Journal of the American Chemical Society)
  • LXR signaling controls homeostatic dendritic cell maturation (2023, Science Immunology)

Frequent collaborators in their research include:

  • Zifu Zhong
  • Bart N. Lambrecht
  • Niek N. Sanders
  • Yong Chen
  • Lutz Nuhn

Best Publications

  • Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

    Behrouz Hassannia;Bartosz Wiernicki;Irina Ingold;Feng Qu

  • Release mechanisms for polyelectrolyte capsules.

    Bruno G. De Geest;Niek N. Sanders;Gleb B. Sukhorukov;Joseph Demeester

  • Polymeric Multilayer Capsules in Drug Delivery

    Liesbeth J. De Cock;Stefaan De Koker;Bruno G. De Geest;Johan Grooten

  • Polymeric multilayer capsules for drug delivery.

    Stefaan De Koker;Richard Hoogenboom;Bruno G. De Geest

  • Polyelectrolyte microcapsules for biomedical applications

    Bruno G. De Geest;Bruno G. De Geest;Stefaan De Koker;Gleb B. Sukhorukov;Oliver Kreft

  • Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction.

    Joeri Tulkens;Glenn Vergauwen;Jan Van Deun;Edward Geeurickx

  • The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth Möhwald

    Shuang Zhao;Frank Caruso;Lars Dahne;Gero Decher;Gero Decher

  • Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross‐Presentation of Encapsulated Antigens

    Stefaan De Koker;Bruno G. De Geest;Satwinder K. Singh;Riet De Rycke

  • Polymeric microcapsules with light responsive properties for encapsulation and release

    Matthieu F. Bédard;Bruno G. De Geest;Andre G. Skirtach;Helmuth Möhwald

  • Ultrasound-Responsive Polymer-Coated Microbubbles That Bind and Protect DNA

    Ine Lentacker;Bruno G. De Geest;Roosmarijn E. Vandenbroucke;Liesbeth Peeters

  • Synthesis of monodisperse biodegradable microgels in microfluidic devices

    Bruno G. De Geest;John Paul Urbanski;Todd Thorsen;Jo Demeester

  • Glucose-responsive polyelectrolyte capsules

    Bruno G. De Geest;Alain M. Jonas;Joseph Demeester;Stefaan C. De Smedt

  • Intracellular processing of proteins mediated by biodegradable polyelectrolyte capsules.

    Pilar Rivera-Gil;Stefaan De Koker;Bruno G. De Geest;Wolfgang J. Parak

  • pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

    Lutz Nuhn;Nane Vanparijs;Ans De Beuckelaer;Lien Lybaert

  • Polymeric multilayer capsules delivering biotherapeutics

    Stefaan De Koker;Liesbeth J. De Cock;Pilar Rivera-Gil;Wolfgang J. Parak

  • Designing polymeric particles for antigen delivery

    Stefaan De Koker;Bart N. Lambrecht;Monique A. Willart;Yvette van Kooyk

  • Ultrasound‐Triggered Release from Multilayered Capsules

    Bruno G. De Geest;Andre G. Skirtach;Arif A. Mamedov;Alexei A. Antipov

  • β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination

    Rebecca De Smet;Tine Demoor;Stephanie Verschuere;Melissa Dullaers

  • Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses.

    Lutz Nuhn;Stefaan De Koker;Sandra Van Lint;Zifu Zhong

  • Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

    Vimal Kumar Udhayakumar;Ans De Beuckelaer;Joanne McCaffrey;Cian M McCrudden

  • Ultrasound stimulated release and catalysis using polyelectrolyte multilayer capsules

    Andre G. Skirtach;Bruno G. De Geest;Arif Mamedov;Alexei A. Antipov

  • Biodegradable microcapsules designed via ‘click’ chemistry

    Bruno G. De Geest;Bruno G. De Geest;Wim Van Camp;Filip E. Du Prez;Stefaan C. De Smedt

Frequent Co-Authors

Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Richard Hoogenboom
Richard Hoogenboom Ghent University
Stefaan C. De Smedt
Stefaan C. De Smedt Ghent University
Johan Grooten
Johan Grooten Ghent University
Olivier De Wever
Olivier De Wever Ghent University
Filip Du Prez
Filip Du Prez Ghent University
Wim E. Hennink
Wim E. Hennink Utrecht University
Riet De Rycke
Riet De Rycke Ghent University
Niek N. Sanders
Niek N. Sanders Ghent University
Gleb B. Sukhorukov
Gleb B. Sukhorukov Queen Mary University of London

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