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Chemistry

D-Index
82
Citations
21556
World Ranking
3138
National Ranking
76

Overview

Pierre-Alain Carrupt is affiliated with the University of Lausanne in Switzerland. Their research spans multiple fields including Chemistry, Pharmacology, Toxicology and Pharmaceutics, and Agricultural and Biological Sciences. The subfields of study they are involved in include Organic Chemistry, Pharmacology, and Plant Science.

Their work covers several main topics, notably chemical synthesis and alkaloids, plant-based medicinal research, and ethnobotanical and medicinal plant studies.

Recent scholarly contributions include a publication titled Zebrafish bioassay-guided isolation of antiseizure compounds from the Cameroonian medicinal plant Cyperus articulatus L, published in 2020 in the journal Phytomedicine.

  • Théo Brillatz
  • Maxime Jacmin
  • Emerson Ferreira Queiroz
  • Laurence Marcourt
  • Ivan Slacanin

  • Phytomedicine

Best Publications

  • Molecular fields in quantitative structure–permeation relationships: the VolSurf approach

    G. Cruciani;P. Crivori;P.-A. Carrupt;B. Testa

  • Predicting Blood−Brain Barrier Permeation from Three-Dimensional Molecular Structure

    Patrizia Crivori;Gabriele Cruciani;Pierre-Alain Carrupt;Bernard Testa

  • Drug-protein binding: a critical review of analytical tools.

    Karine Vuignier;Julie Schappler;Jean-Luc Veuthey;Pierre-Alain Carrupt

  • Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase

    Corinne Brühlmann;Frédéric Ooms;Pierre-Alain Carrupt;Bernard Testa

  • HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

    Claudia Simões-Pires;Vincent Zwick;Alessandra Nurisso;Esther Schenker

  • Molecular Lipophilicity Potential, a tool in 3D QSAR: Method and applications

    Patrick Gaillard;Pierre-Alain Carrupt;Bernard Testa;Alain Boudon

  • Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs.

    Carmela Gnerre;Marco Catto;Francesco Leonetti;Peter Weber

  • Stereoselective Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers

    C. B. Eap;S. Crettol;J.-S. Rougier;J. Schläpfer

  • The influence of lipophilicity on the pharmacokinetic behavior of drugs: Concepts and examples

    Bernard Testa;Patrizia Crivori;Marianne Reist;Pierre-Alain Carrupt

  • Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants

    J. Ancerewicz;E. Migliavacca;Pierre-Alain Carrupt;Bernard Testa

  • Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity

    Pierre Alain Carrupt;Bernard Testa;Antoine Bechalany;Nabil El Tayar

  • Monoamine oxidase inhibition by Rhodiola rosea L. roots.

    Daphne van Diermen;Andrew Marston;Juan Bravo;Marianne Reist

  • Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.

    Giorgio Ottaviani;Sophie Martel;Pierre-Alain Carrupt

  • Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.

    Ahcène Boumendjel;Julien Boccard;Pierre-Alain Carrupt;Edwige Nicolle

  • Partitioning of solutes in different solvent systems: The contribution of hydrogen‐bonding capacity and polarity

    Nabil El Tayar;Ruey-Shiuan Tsai;Bernard Testa;Pierre-Alain Carrupt

  • Percutaneous Penetration of Drugs: A Quantitative Structure–Permeability Relationship Study

    Nabil El Tayar;Ruey-Shiuan Tsai;Bernard Testa;Pierre-Alain Carrupt

  • Racemization, Enantiomerization, Diastereomerization, and Epimerization - Their Meaning and Pharmacological Significance

    Marianne Reist;Bernard Testa;Pierre-Alain Carrupt;Martin Jung

  • Lipophilicity in molecular modeling

    Bernard Testa;Pierre-Alain Carrupt;Patrick Gaillard;Frédéric Billois

  • Liposome/water lipophilicity: methods, information content, and pharmaceutical applications.

    Georgette Plemper van Balen;Catherine a Marca Martinet;Giulia Caron;Géraldine Bouchard

  • Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening

    Laura Novaroli;Marianne Reist;Elisabeth Favre;Angelo Carotti

Frequent Co-Authors

Bernard Testa
Bernard Testa University of Lausanne
Pierre Vogel
Pierre Vogel École Polytechnique Fédérale de Lausanne
Hubert H. Girault
Hubert H. Girault École Polytechnique Fédérale de Lausanne
Jean-Luc Veuthey
Jean-Luc Veuthey University of Geneva
Serge Rudaz
Serge Rudaz University of Geneva
Jean-Luc Wolfender
Jean-Luc Wolfender University of Geneva
Angelo Carotti
Angelo Carotti University of Bari Aldo Moro
Davy Guillarme
Davy Guillarme University of Geneva
Kurt Hostettmann
Kurt Hostettmann University of Geneva
Peter Jenner
Peter Jenner King's College London

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