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Jean-Luc Wolfender

Jean-Luc Wolfender

D-Index & Metrics

Chemistry

D-Index
75
Citations
28477
World Ranking
4368
National Ranking
101

Overview

Jean-Luc Wolfender is affiliated with the University of Geneva in Switzerland. Their work spans several interconnected fields, predominantly in biochemistry, genetics, and molecular biology, with significant contributions also to medicine. The major subfields covered in their research include molecular biology, pharmacology, plant science, biochemistry, and complementary and alternative medicine.

The scientist's research topics focus extensively on areas related to natural products and their biological activities. Key topics of interest include microbial natural products and biosynthesis, metabolomics and mass spectrometry studies, plant biochemistry and biosynthesis, computational drug discovery methods, natural product bioactivities and synthesis, analytical chemistry and chromatography, and phytochemicals and antioxidant activities.

Jean-Luc Wolfender has authored numerous publications, including recent papers such as:

  • The LOTUS initiative for open knowledge management in natural products research (2022), published in eLife
  • Wound- and mechanostimulated electrical signals control hormone responses (2020), published in New Phytologist
  • Spatial and evolutionary predictability of phytochemical diversity (2021), published in Proceedings of the National Academy of Sciences
  • Functional Traits 2.0: The power of the metabolome for ecology (2022), published in Journal of Ecology
  • Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review (2022), published in Pharmacological Research

The scientist frequently publishes in venues such as Planta Medica, bioRxiv (Cold Spring Harbor Laboratory), Phytochemistry Letters, Frontiers in Chemistry, and Journal of Natural Products.

In collaborative efforts, Jean-Luc Wolfender commonly works with co-authors including Laurence Marcourt, Emerson Ferreira Queiroz, Pierre-Marie Allard, Adriano Rutz, and Katia Gindro. These collaborations reflect a broad and interdisciplinary approach to studying natural products, plant science, and related biochemical processes.

Best Publications

  • Natural products in drug discovery: advances and opportunities.

    Atanas G Atanasov;Sergey B Zotchev;Verena M Dirsch

  • Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

    Mingxun Wang;Jeremy J Carver;Vanessa V Phelan;Laura M Sanchez

  • The pharmaceutical industry and natural products: historical status and new trends

    Bruno David;Jean-Luc Wolfender;Daniel A. Dias

  • Current approaches and challenges for the metabolite profiling of complex natural extracts

    Jean-Luc Wolfender;Guillaume Marti;Aurélien Thomas;Samuel Bertrand

  • Metabolite induction via microorganism co-culture: A potential way to enhance chemical diversity for drug discovery

    Samuel Bertrand;Nadine Bohni;Sylvain Schnee;Olivier Schumpp

  • Integration of Molecular Networking and In-Silico MS/MS Fragmentation for Natural Products Dereplication

    Pierre-Marie Allard;Tiphaine Péresse;Jonathan Bisson;Katia Gindro

  • The Potential of African Plants as a Source of Drugs

    Kurt Hostettmann;Andrew Marston;Karine Ndjoko;Jean-Luc Wolfender

  • Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for the differentiation of C-glycosidic flavonoid isomers.

    Patrice Waridel;Jean-Luc Wolfender;Karine Ndjoko;Kirsten R. Hobby

  • Spatial and Temporal Dynamics of Jasmonate Synthesis and Accumulation in Arabidopsis in Response to Wounding

    Gaetan Glauser;Elia Grata;Lucie Dubugnon;Serge Rudaz

  • Antileishmanial Activity of Dimeric Flavonoids Isolated from Arrabidaea brachypoda

    Vinícius P. C. Rocha;Cláudia Quintino da Rocha;Emerson Ferreira Queiroz;Laurence Marcourt

  • Velocity estimates for signal propagation leading to systemic jasmonic acid accumulation in wounded Arabidopsis.

    Gaetan Glauser;Lucie Dubugnon;Seyed A.R. Mousavi;Serge Rudaz

  • Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography-High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics.

    Jean Luc Wolfender;Jean Marc Nuzillard;Justin J.J. Van Der Hooft;Jean Hugues Renault

  • Metabolite identification: are you sure? And how do your peers gauge your confidence?

    Darren John Creek;Warwick B Dunn;Oliver Fiehn;Julian L Griffin

  • Induction and detoxification of maize 1,4-benzoxazin-3-ones by insect herbivores

    Gaétan Glauser;Guillaume Marti;Neil Villard;Gwladys A. Doyen

  • Four 13-lipoxygenases contribute to rapid jasmonate synthesis in wounded Arabidopsis thaliana leaves: a role for lipoxygenase 6 in responses to long-distance wound signals.

    Adeline Chauvin;Daniela Caldelari;Jean‐Luc Wolfender;Edward E. Farmer

  • Plant metabolomics: from holistic data to relevant biomarkers.

    Jean-Luc Wolfender;Serge Rudaz;Young Hae Choi;Hye Kyong Kim

  • Liquid chromatography with ultraviolet absorbance–mass spectrometric detection and with nuclear magnetic resonance spectrometry: a powerful combination for the on-line structural investigation of plant metabolites

    Jean-Luc Wolfender;Karine Ndjoko;Kurt Hostettmann

  • HPLC in natural product analysis: the detection issue.

    Jean-Luc Wolfender

  • Liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy for the screening of plant constituents

    J.-L Wolfender;S Rodriguez;K Hostettmann

  • Metabolomics reveals herbivore‐induced metabolites of resistance and susceptibility in maize leaves and roots

    Guillaume Marti;Matthias Erb;Julien Boccard;Gaétan Glauser

  • The potential of LC-NMR in phytochemical analysis.

    Jean-Luc Wolfender;Karine Ndjoko;Kurt Hostettmann

  • Innovative omics-based approaches for prioritisation and targeted isolation of natural products – new strategies for drug discovery

    Jean-Luc Wolfender;Marc Litaudon;David Touboul;Emerson Ferreira Queiroz

Frequent Co-Authors

Kurt Hostettmann
Kurt Hostettmann University of Geneva
Serge Rudaz
Serge Rudaz University of Geneva
Gaétan Glauser
Gaétan Glauser University of Neuchâtel
Pierre-Alain Carrupt
Pierre-Alain Carrupt École Polytechnique Fédérale de Lausanne
Davy Guillarme
Davy Guillarme University of Geneva
Matthias Hamburger
Matthias Hamburger University of Basel
Michel Monod
Michel Monod University Hospital of Lausanne
Edward E. Farmer
Edward E. Farmer University of Lausanne
Ted C. J. Turlings
Ted C. J. Turlings University of Neuchâtel
Matthias Erb
Matthias Erb University of Bern

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