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Chemistry

D-Index
92
Citations
29183
World Ranking
1890
National Ranking
40

Overview

Bernard Testa is affiliated with the University of Lausanne in Switzerland. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, contributing to a total of nine and seven publications respectively in these main fields of study.

Their work spans several subfields including molecular biology, infectious diseases, epidemiology, oncology, and toxicology. Major topics covered in their research include tuberculosis research and epidemiology, cancer therapeutics and mechanisms, phenothiazines and benzothiazines synthesis and activities, mycobacterium research and diagnosis, drug transport and resistance mechanisms, bioactive compounds and antitumor agents, and pharmacogenetics and drug metabolism.

Bernard Testa has published research in multiple venues, with frequent contributions to the following:

  • Pharmaceuticals
  • Proceedings of 7th International Electronic Conference on Medicinal Chemistry
  • European Journal of Pharmaceutical Sciences
  • Burger's Medicinal Chemistry and Drug Discovery

Their recent papers include:

  • Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis, 2022, Pharmaceuticals
  • Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis, 2021, European Journal of Pharmaceutical Sciences
  • Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection, 2022, Pharmaceuticals
  • Fluoroquinolone derivatives in the treatment of mycobacterium tuberculosis infection, 2021, Proceedings of 7th International Electronic Conference on Medicinal Chemistry
  • Benzoic acid derivatives as prodrugs for the treatment of tuberculosis, 2021, Proceedings of 7th International Electronic Conference on Medicinal Chemistry

Frequent co-authors associated with Bernard Testa include:

  • Luís Constantino
  • João P. Pais
  • David Pires
  • Elsa Anes
  • Emília Valente

Best Publications

  • Advances in Drug Research

    Bernard;Meyer Testa;Urs A Meyer;Bernard Testa

  • In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling

    S Ekins;J Mestres;B Testa

  • Molecular fields in quantitative structure–permeation relationships: the VolSurf approach

    G. Cruciani;P. Crivori;P.-A. Carrupt;B. Testa

  • Prodrug research: futile or fertile?

    Bernard Testa

  • Predicting Blood−Brain Barrier Permeation from Three-Dimensional Molecular Structure

    Patrizia Crivori;Gabriele Cruciani;Pierre-Alain Carrupt;Bernard Testa

  • Inhibitors of Cytochrome P-450s and their mechanism of action.

    Bernard Testa;Peter Jenner

  • Predicting drug metabolism: experiment and/or computation?

    Johannes Kirchmair;Andreas H Göller;Dieter Lang;Jens Kunze

  • Lipophilicity and Its Relationship with Passive Drug Permeation

    Xiangli Liu;Bernard Testa;Alfred Fahr

  • In silico pharmacology for drug discovery: applications to targets and beyond

    S Ekins;J Mestres;B Testa

  • Hydrolysis in drug and prodrug metabolism : chemistry, biochemistry, and enzymology

    Bernard Testa;Joachim M. Mayer

  • Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase

    Corinne Brühlmann;Frédéric Ooms;Pierre-Alain Carrupt;Bernard Testa

  • Molecular Lipophilicity Potential, a tool in 3D QSAR: Method and applications

    Patrick Gaillard;Pierre-Alain Carrupt;Bernard Testa;Alain Boudon

  • Assessing drug-likeness--what are we missing?

    Giulio Vistoli;Alessandro Pedretti;Bernard Testa

  • Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs.

    Carmela Gnerre;Marco Catto;Francesco Leonetti;Peter Weber

  • The influence of lipophilicity on the pharmacokinetic behavior of drugs: Concepts and examples

    Bernard Testa;Patrizia Crivori;Marianne Reist;Pierre-Alain Carrupt

  • Solvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: Evidence from partition coefficients and molecular dynamics simulations

    el Tayar N;Mark Ae;Vallat P;Brunne Rm

  • Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants

    J. Ancerewicz;E. Migliavacca;Pierre-Alain Carrupt;Bernard Testa

  • Reactions and enzymes in the metabolism of drugs and other xenobiotics.

    Bernard Testa;Alessandro Pedretti;Giulio Vistoli

  • Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity

    Pierre Alain Carrupt;Bernard Testa;Antoine Bechalany;Nabil El Tayar

  • The Skin as a Drug-Metabolizing Organ

    A. Pannatier;P. Jenner;B. Testa;J. C. Etter

  • QSAR: Hansch analysis and related approaches

    Bernard Testa

Frequent Co-Authors

Pierre-Alain Carrupt
Pierre-Alain Carrupt École Polytechnique Fédérale de Lausanne
Peter Jenner
Peter Jenner King's College London
Angelo Carotti
Angelo Carotti University of Bari Aldo Moro
Lemont B. Kier
Lemont B. Kier Virginia Commonwealth University
Hubert H. Girault
Hubert H. Girault École Polytechnique Fédérale de Lausanne
Charles David Marsden
Charles David Marsden King's College London
Kurt Hostettmann
Kurt Hostettmann University of Geneva
Gabriele Cruciani
Gabriele Cruciani University of Perugia
Roméo Cecchelli
Roméo Cecchelli Artois University
Michael Spedding
Michael Spedding DuPont (United States)

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