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Medicine

D-Index
95
Citations
31682
World Ranking
10103
National Ranking
398

Overview

Clemens W.G.M. Löwik is affiliated with Erasmus University Rotterdam in the Netherlands. Their research spans multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Engineering, with a prominent focus on Biomedical Engineering, Molecular Biology, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, and Oncology.

Their work involves investigation into several main topics such as:

  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Bioluminescence and chemiluminescence research
  • Cancer, Hypoxia, and Metabolism
  • Advanced Biosensing Techniques and Applications
  • Thyroid Cancer Diagnosis and Treatment
  • Virus-based gene therapy research

Key publications reflect the scope of their research contributions. Examples of recent papers include:

  • "Real-time fluorescence imaging in intraoperative decision making for cancer surgery," 2021, The Lancet Oncology
  • "Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session," 2020, Journal of Controlled Release
  • "NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform," 2020, International Journal of Molecular Sciences
  • "pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology," 2020, Cancers
  • "Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice," 2021, Journal of Photochemistry and Photobiology B Biology

Frequent coauthors who have collaborated with Löwik include:

  • Laura Mezzanotte
  • Dominic J. Robinson
  • Giorgia Zambito
  • Kranthi M. Panth
  • Henriëtte S. de Bruijn

Their research has appeared regularly in notable publication venues such as:

  • Molecular Imaging and Biology
  • International Journal of Molecular Sciences
  • Cancers
  • Theranostics
  • European Journal of Nuclear Medicine and Molecular Imaging

Best Publications

  • Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

    Kenneth E. S. Poole;Rutger L. Van Bezooijen;Nigel Loveridge;Herman Hamersma

  • Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist

    Rutger L. van Bezooijen;Bernard A.J. Roelen;Annemieke Visser;Lianne van der Wee-Pals

  • The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery

    Boudewijn E. Schaafsma;J. Sven D. Mieog;Merlijn Hutteman;Joost R. van der Vorst

  • Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A

    Martine M. L. Deckers;Rutger L. van Bezooijen;Geertje van der Horst;Jakomijn Hoogendam

  • Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation.

    Martine M. L. Deckers;Marcel Karperien;Chris van der Bent;Takeyoshi Yamashita

  • Mesenchymal stem cells promote engraftment of human umbilical cord blood–derived CD34+ cells in NOD/SCID mice

    Willy A Noort;Alwine B Kruisselbrink;Pieternella S in't Anker;Marjolein Kruger

  • Farnesyl Pyrophosphate Synthase Is the Molecular Target of Nitrogen-Containing Bisphosphonates

    E. van Beek;E. Pieterman;L. Cohen;C. Löwik

  • BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.

    Marion Scharpfenecker;M. van Dinther;Zhen Liu;R.L. van Bezooijen

  • Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding

    Noriko Yamaguchi;Bela Anand-Apte;Margaret Lee;Takako Sasaki

  • The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells

    Martine Deckers;Maarten van Dinther;Jeroen Buijs;Ivo Que

  • Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis.

    C.W.G.M. Löwik;G. van der Pluijm;H. Bloys;K. Hoekman

  • Peroxisome Proliferator-activated Receptor γ (PPARγ) as a Molecular Target for the Soy Phytoestrogen Genistein

    Zhi-Chao Dang;Valérie Audinot;Socrates E. Papapoulos;Jean A. Boutin

  • Sclerostin: Current Knowledge and Future Perspectives

    M. J. C. Moester;S. E. Papapoulos;C. W. G. M. Löwik;R. L. van Bezooijen

  • Wnt but Not BMP Signaling Is Involved in the Inhibitory Action of Sclerostin on BMP-Stimulated Bone Formation

    Rutger L. van Bezooijen;J. Peter Svensson;J. Peter Svensson;Daniël Eefting;Annemieke Visser

  • Differential Expression of Estrogen Receptors α and β mRNA During Differentiation of Human Osteoblast SV-HFO Cells

    Janine Arts;George G. J. M. Kuiper;Josine M. M. F. Janssen;Jan-Åke Gustafsson

  • SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

    Rutger L. van Bezooijen;Peter ten Dijke;Socrates E. Papapoulos;Clemens W. G.M. Löwik

  • Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

    Blandine Franke-Fayard;Chris J. Janse;Margarida Cunha-Rodrigues;Jai Ramesar

  • Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro.

    G van der Pluijm;H Vloedgraven;E van Beek;L van der Wee-Pals

  • In vivo imaging of transcriptionally active estrogen receptors

    Paolo Ciana;Michele Raviscioni;Paola Mussi;Elisabetta Vegeto

  • The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates.

    Ermond Van Beek;Clemens Löwik;Gabri Van Der Pluijm;Socrates Papapoulos

Frequent Co-Authors

Socrates E. Papapoulos
Socrates E. Papapoulos Leiden University Medical Center
Marcel Karperien
Marcel Karperien University of Twente
Boudewijn P. F. Lelieveldt
Boudewijn P. F. Lelieveldt Leiden University Medical Center
Cornelis J.H. van de Velde
Cornelis J.H. van de Velde Leiden University Medical Center
John V. Frangioni
John V. Frangioni Beth Israel Deaconess Medical Center
Paul H.A. Quax
Paul H.A. Quax Leiden University Medical Center
Peter ten Dijke
Peter ten Dijke Leiden University Medical Center
George N. Thalmann
George N. Thalmann University of Bern
Urs E. Studer
Urs E. Studer University of Bern
Wim Jiskoot
Wim Jiskoot Leiden University

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