D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 9,567 101 World Ranking 15599 National Ranking 1117

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Amino acid
  • Neurotransmitter

The scientist’s investigation covers issues in Glycine receptor, Biochemistry, NMDA receptor, Neuroscience and Receptor. His Glycine receptor research incorporates themes from Agonist, Molecular biology, Biophysics and Inhibitory postsynaptic potential. His Biochemistry study typically links adjacent topics like Alpha.

His research in NMDA receptor tackles topics such as Glycine binding which are related to areas like Ionotropic effect, Phenylalanine and Glutamate receptor. His work focuses on many connections between Neuroscience and other disciplines, such as Neurotransmission, that overlap with his field of interest in Drug discovery, Allosteric regulation, Nicotinic acetylcholine receptor, Ion channel and Synaptic plasticity. The various areas that Bodo Laube examines in his Receptor study include Endocrinology, Strychnine, Hereditary hyperekplexia and Brainstem.

His most cited work include:

  • Evidence for a Tetrameric Structure of Recombinant NMDA Receptors (434 citations)
  • Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. (412 citations)
  • Loss of Postsynaptic GABAA Receptor Clustering in Gephyrin-Deficient Mice (390 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Glycine receptor, Biochemistry, NMDA receptor, Protein subunit and Biophysics. His Glycine receptor study necessitates a more in-depth grasp of Glycine. His NMDA receptor research is multidisciplinary, incorporating elements of Glutamate receptor and Glycine binding.

He combines subjects such as Xenopus, Transmembrane protein, Wild type, Transmembrane domain and Cell biology with his study of Protein subunit. His Biophysics study integrates concerns from other disciplines, such as Long-term potentiation and Cys-loop receptors. In his research, Neurotransmission is intimately related to Neuroscience, which falls under the overarching field of Receptor.

He most often published in these fields:

  • Glycine receptor (63.55%)
  • Biochemistry (47.66%)
  • NMDA receptor (35.51%)

What were the highlights of his more recent work (between 2013-2021)?

  • Biophysics (39.25%)
  • Glutamate receptor (14.95%)
  • NMDA receptor (35.51%)

In recent papers he was focusing on the following fields of study:

Bodo Laube mainly focuses on Biophysics, Glutamate receptor, NMDA receptor, Receptor and Protein subunit. His research in Biophysics intersects with topics in Agonist, AMPA receptor and Glycine receptor. The Agonist study combines topics in areas such as Glycine and Ion channel.

His biological study spans a wide range of topics, including Neuroscience and Cys-loop receptors. Glutamate receptor is a subfield of Biochemistry that Bodo Laube tackles. Bodo Laube does research in NMDA receptor, focusing on Memantine specifically.

Between 2013 and 2021, his most popular works were:

  • GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy. (131 citations)
  • GRIN2B encephalopathy : Novel findings on phenotype, variant clustering, functional consequences and treatment aspects (84 citations)
  • Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy (82 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Amino acid
  • Genetics

Bodo Laube focuses on Intellectual disability, Autism, Epilepsy, Chloride channel and Ligand-gated ion channel. His Intellectual disability study incorporates themes from Mutation, Consanguinity, Phenotype and GRIN1. His work deals with themes such as GRIN2B, Encephalopathy and Pediatrics, which intersect with Epilepsy.

His Chloride channel research is multidisciplinary, incorporating elements of Amino acid, Postsynaptic potential, Pharmacology and Binding site. As part of his inquiry into Biochemistry and Ion channel, Bodo Laube is doing Ligand-gated ion channel research. The various areas that Bodo Laube examines in his Biophysics study include Agonist, Propofol, Glycine receptor and Glutamic acid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

Bodo Laube;Jochen Kuhse;Heinrich Betz.
The Journal of Neuroscience (1998)

686 Citations

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.

Bodo Laube;Hirokazu Hirai;Mike Sturgess;Heinrich Betz.
Neuron (1997)

647 Citations

Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins

Alexander Kuryatov;Bodo Laube;Heinrich Betz;Jochen Kuhse.
Neuron (1994)

554 Citations

Loss of Postsynaptic GABAA Receptor Clustering in Gephyrin-Deficient Mice

Matthias Kneussel;Johann Helmut Brandstätter;Bodo Laube;Sabine Stahl.
The Journal of Neuroscience (1999)

505 Citations

The β Subunit Determines the Ligand Binding Properties of Synaptic Glycine Receptors

Joanna Grudzinska;Rudolf Schemm;Svenja Haeger;Annette Nicke.
Neuron (2005)

480 Citations

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

Sabine Endele;Georg Rosenberger;Kirsten Geider;Bernt Popp.
Nature Genetics (2010)

477 Citations

Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes

Johannes R Lemke;Dennis Lal;Eva M Reinthaler;Isabelle Steiner.
Nature Genetics (2013)

423 Citations

Glycine receptors: recent insights into their structural organization and functional diversity.

Heinrich Betz;Bodo Laube.
Journal of Neurochemistry (2006)

372 Citations

Deletion of the Mouse Glycine Transporter 2 Results in a Hyperekplexia Phenotype and Postnatal Lethality

Jesús Gomeza;Koji Ohno;Swen Hülsmann;Wencke Armsen.
Neuron (2003)

325 Citations

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region

Hirokazu Hirai;Joachim Kirsch;Bodo Laube;Heinrich Betz.
Proceedings of the National Academy of Sciences of the United States of America (1996)

325 Citations

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