World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
21570
World Ranking
7283
National Ranking
184

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

Robert J. Harvey mainly focuses on Genetics, Glycine receptor, Cell biology, Mutation and Collybistin. In general Genetics, his work in Mutant, Single-nucleotide polymorphism and Association mapping is often linked to Livestock linking many areas of study. Particularly relevant to Hyperekplexia is his body of work in Glycine receptor.

His Cell biology study incorporates themes from Biochemistry, PINK1 and Point mutation. Robert J. Harvey combines subjects such as Gephyrin, Postsynaptic potential and Alternative splicing with his study of Collybistin. The various areas that he examines in his Postsynaptic potential study include Inhibitory postsynaptic potential, Neuroscience and Neurotransmission.

His most cited work include:

  • Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. (600 citations)
  • GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. (481 citations)
  • The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1 (393 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Glycine receptor, Neuroscience, Cell biology, Genetics and GABAA receptor. His research integrates issues of Inhibitory postsynaptic potential and Postsynaptic potential in his study of Glycine receptor. As part of one scientific family, he deals mainly with the area of Postsynaptic potential, narrowing it down to issues related to the Collybistin, and often Pleckstrin homology domain.

His research on Neuroscience also deals with topics like

  • Neurotransmission, which have a strong connection to Synaptic plasticity,
  • Zebrafish that connect with fields like Gene knockdown. His Cell biology study integrates concerns from other disciplines, such as Mutant and Excitatory postsynaptic potential. His GABAA receptor study combines topics from a wide range of disciplines, such as Molecular biology, Protein subunit and gamma-Aminobutyric acid.

He most often published in these fields:

  • Glycine receptor (45.51%)
  • Neuroscience (25.15%)
  • Cell biology (25.15%)

What were the highlights of his more recent work (between 2014-2021)?

  • Glycine receptor (45.51%)
  • Cell biology (25.15%)
  • Neuroscience (25.15%)

In recent papers he was focusing on the following fields of study:

Robert J. Harvey focuses on Glycine receptor, Cell biology, Neuroscience, Mutant and Inhibitory postsynaptic potential. The Glycine receptor study combines topics in areas such as Endocrinology, Agonist, Biophysics, Internal medicine and Strychnine. Robert J. Harvey has included themes like Hyperekplexia, Glycine, Gene knockdown and Mutation in his Cell biology study.

His Mutation research integrates issues from HEK 293 cells and Receptor. His studies in Neuroscience integrate themes in fields like Knockout mouse and Neurotransmission. His research in Inhibitory postsynaptic potential intersects with topics in Gephyrin, Scaffold protein and GABAA receptor.

Between 2014 and 2021, his most popular works were:

  • Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures (104 citations)
  • Clinical and Immunologic Investigations in Patients With Stiff-Person Spectrum Disorder (72 citations)
  • Antibodies to Aquaporin 4, Myelin-Oligodendrocyte Glycoprotein, and the Glycine Receptor α1 Subunit in Patients With Isolated Optic Neuritis (71 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

Robert J. Harvey mostly deals with Epilepsy, Missense mutation, Glycine receptor, Neuroscience and Mutation. His Missense mutation study also includes

  • Candidate gene together with DNA sequencing, X chromosome, Exome and GTPase,
  • Locus which connect with Exome sequencing, Collybistin and Gephyrin. In his study, Robert J. Harvey carries out multidisciplinary Glycine receptor and Pentylenetetrazol research.

His Neuroscience research is multidisciplinary, incorporating perspectives in Genetic heterogeneity and Neurotransmission. He focuses mostly in the field of Mutation, narrowing it down to matters related to Receptor and, in some cases, Binding site and Cell biology. His work on Symporter as part of general Genetics study is frequently linked to In patient, therefore connecting diverse disciplines of science.

Best Publications

  • Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1

    Eriza Maria Valente;Patrick M. Abou-Sleiman;Viviana Caputo;Miratul M K Muqit

  • Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.

    Elisa Greggio;Shushant Jain;Ann Kingsbury;Rina Bandopadhyay

  • GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization.

    Robert J. Harvey;Ulrike B. Depner;Heinz Wässle;Seifollah Ahmadi

  • The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

    Hélène Plun-Favreau;Kristina Klupsch;Nicoleta Moisoi;Sonia Gandhi

  • Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin

    Alexandros Poulopoulos;Gayane Aramuni;Guido Meyer;Tolga Soykan

  • PINK1 cleavage at position A103 by the mitochondrial protease PARL

    Emma Deas;Helene Plun-Favreau;Sonia Gandhi;Howard Desmond

  • Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes

    Johannes R Lemke;Dennis Lal;Eva M Reinthaler;Isabelle Steiner

  • Mutations in α-Tubulin Cause Abnormal Neuronal Migration in Mice and Lissencephaly in Humans

    David A. Keays;Guoling Tian;Karine Poirier;Guo Jen Huang

  • Gephyrin: where do we stand, where do we go?

    Jean-Marc Fritschy;Robert J. Harvey;Günter Schwarz

  • Highly effective SNP-based association mapping and management of recessive defects in livestock

    Carole Charlier;Wouter Coppieters;Frédéric Rollin;Daniel Desmecht

  • Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity.

    Alastair M. Hosie;Emma L. Dunne;Robert J. Harvey;Trevor G. Smart

  • The GDP-GTP Exchange Factor Collybistin: An Essential Determinant of Neuronal Gephyrin Clustering

    Kirsten Harvey;Ian C Duguid;Melissa J. Alldred;Sarah E. Beatty

  • Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.

    Mark I. Rees;Mark I. Rees;Kirsten Harvey;Brian R. Pearce;Seo-Kyung Chung;Seo-Kyung Chung

  • Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).

    Karine Poirier;Karine Poirier;David A. Keays;Fiona Francis;Fiona Francis;Yoann Saillour;Yoann Saillour

  • GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.

    Johannes R Lemke;Rik Hendrickx;Kirsten Geider;Bodo Laube

  • Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain

    Robert J. Harvey;Benjamin K. Yee

  • Glycine receptor autoimmune spectrum with stiff-man syndrome phenotype

    Andrew McKeon;Eugenia Martinez-Hernandez;Eric Lancaster;Joseph Y. Matsumoto

  • The genetics of hyperekplexia: more than startle!

    Robert J. Harvey;Maya Topf;Kirsten Harvey;Mark I. Rees;Mark I. Rees

  • TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins

    Ravinesh A. Kumar;Daniela T. Pilz;Timothy D. Babatz;Thomas D. Cushion

  • Effects of subunit types of the recombinant GABAA receptor on the response to a neurosteroid.

    Shahid H. Zaman;Ryuzo Shingai;Robert J. Harvey;Mark G. Darlison

Frequent Co-Authors

Mark G. Darlison
Mark G. Darlison Edinburgh Napier University
Mark I. Rees
Mark I. Rees Swansea University
Trevor G. Smart
Trevor G. Smart University College London
Heinrich Betz
Heinrich Betz Max Planck Society
Joseph W. Lynch
Joseph W. Lynch University of Queensland
Ulrike Müller
Ulrike Müller Heidelberg University
Nicholas W. Wood
Nicholas W. Wood University College London
David S. Latchman
David S. Latchman University College London
Eric A. Barnard
Eric A. Barnard University of Cambridge
Heinz Wässle
Heinz Wässle Max Planck Society

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