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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
23952
World Ranking
5249
National Ranking
382

Overview

Ulrike Müller is affiliated with Heidelberg University in Germany and has a research focus spanning medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their subfields of study include physiology, cellular and molecular neuroscience, molecular biology, neurology, and cell biology.

Their research primarily addresses topics related to Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, genetics and neurodevelopmental disorders, cellular transport and secretion, neuroinflammation and neurodegeneration mechanisms, Parkinson's disease mechanisms and treatments, and neurogenesis and neuroplasticity mechanisms.

Müller has published extensively in several prominent scientific venues, with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory), the Journal of Neuroscience, Alzheimer's & Dementia, Nature Communications, and The EMBO Journal.

Recent papers authored or co-authored by Müller include:

  • APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?, 2022, Alzheimer's & Dementia
  • Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype, 2021, The EMBO Journal
  • Amyloid-Beta Mediates Homeostatic Synaptic Plasticity, 2021, Journal of Neuroscience
  • Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model, 2020, Molecular Neurodegeneration
  • Lack of APP and APLP2 in GABAergic Forebrain Neurons Impairs Synaptic Plasticity and Cognition, 2020, Cerebral Cortex

Collaborations have been frequent with other researchers including Martin Körte, Susann Ludewig, Susanne Erdinger, David P Wolfer, and Charlotte Bold.

Best Publications

  • Functional role of type I and type II interferons in antiviral defense.

    Ulrike Müller;Ulrich Steinhoff;Luiz F. L. Reis;Silvio Hemmi

  • Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA

    Olivier Cases;Isabelle Seif;Joseph Grimsby;Patricia Gaspar

  • GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization.

    Robert J. Harvey;Ulrike B. Depner;Heinz Wässle;Seifollah Ahmadi

  • Not just amyloid: physiological functions of the amyloid precursor protein family

    Ulrike C. Müller;Thomas Deller;Martin Korte

  • Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members

    Sabine Heber;Jochen Herms;Vladan Gajic;Johannes Hainfellner

  • Loss of Postsynaptic GABAA Receptor Clustering in Gephyrin-Deficient Mice

    Matthias Kneussel;Johann Helmut Brandstätter;Bodo Laube;Sabine Stahl

  • Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

    Marcus O W Grimm;Heike S Grimm;Andreas J Pätzold;Eva G Zinser

  • The Secreted -Amyloid Precursor Protein Ectodomain APPs Is Sufficient to Rescue the Anatomical, Behavioral, and Electrophysiological Abnormalities of APP-Deficient Mice

    Sabine Ring;Sascha W. Weyer;Susanne B. Kilian;Elaine Waldron

  • Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone

    Isabelle Caillé;Bernadette Allinquant;Edmond Dupont;Colette Bouillot

  • Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis.

    Ulrike Müller

  • Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

    Boris Strilic;Lida Yang;Julián Albarrán-Juárez;Laurens Wachsmuth

  • Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

    Jochen Herms;Brigitte Anliker;Sabine Heber;Sabine Ring

  • Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors.

    M. F. Van Den Broek;U. Muller;Sui Huang;M. Aguet

  • Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP

    Raphaëlle Pardossi-Piquard;Agnès Petit;Toshitaka Kawarai;Claire Sunyach

  • High prevalence of Echinococcus multilocularis in urban red foxes (Vulpes vulpes) and voles (Arvicola terrestris) in the city of Zürich, Switzerland.

    S. Hofer;S. Gloor;U. Müller;A. Mathis

  • η-Secretase processing of APP inhibits neuronal activity in the hippocampus

    Michael Willem;Sabina Tahirovic;Marc Aurel Busche;Marc Aurel Busche;Saak V. Ovsepian

  • BEHAVIORAL AND ANATOMICAL DEFICITS IN MICE HOMOZYGOUS FOR A MODIFIED BETA -AMYLOID PRECURSOR PROTEIN GENE

    Ulrike Müller;Nadine Cristina;Zhi-Wei Li;David P. Wolfer

  • Immune defence in mice lacking type I and/or type II interferon receptors

    M. F. Van Den Broek;U. Müller;Sui Huang;R. M. Zinkernagel

  • Physiological Functions of APP Family Proteins

    Ulrike C. Müller;Hui Zheng

  • A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP

    Malcolm A. Leissring;M. Paul Murphy;Tonya R. Mead;Yama Akbari

Frequent Co-Authors

David P. Wolfer
David P. Wolfer University of Zurich
Martin Korte
Martin Korte Technische Universität Braunschweig
Thomas Deller
Thomas Deller Goethe University Frankfurt
Carlos G. Dotti
Carlos G. Dotti Spanish National Research Council
Gerhard Schuler
Gerhard Schuler Leipzig University
Stefan F. Lichtenthaler
Stefan F. Lichtenthaler German Center for Neurodegenerative Diseases
Tobias Hartmann
Tobias Hartmann Saarland University
Hans-Peter Lipp
Hans-Peter Lipp University of Zurich
Heinz Wässle
Heinz Wässle Max Planck Society

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