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Immunology

D-Index
67
Citations
15291
World Ranking
2676
National Ranking
177

Overview

Karl S. Lang is affiliated with the University of Duisburg-Essen in Germany. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a notable concentration on Immunology, Molecular Biology, Oncology, Infectious Diseases, and Epidemiology as subfields.

Their work covers various main topics including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Cancer Immunotherapy and Biomarkers
  • Interferon and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • Immune Response and Inflammation

Among recent papers authored by Karl S. Lang are:

  • "Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells" (2020), published in Cell Reports Medicine
  • "Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression" (2022), published in Nature Communications
  • "During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes" (2022), published in Cell Reports
  • "Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy" (2020), published in Journal of Clinical Investigation
  • "Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications" (2020), published in Journal of Experimental & Clinical Cancer Research

Frequent coauthors collaborating with Karl S. Lang include:

  • Philipp A. Lang
  • Aleksandra A. Pandyra
  • Judith Lang
  • Haifeng C. Xu
  • Lamin B. Cham

Publication venues where Karl S. Lang has frequently contributed include:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports
  • Pathogens

Best Publications

  • Mechanisms of suicidal erythrocyte death.

    Karl S Lang;Philipp A Lang;Christian Bauer;Christophe Duranton

  • Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.

    Karl S Lang;Mike Recher;Tobias Junt;Alexander A Navarini

  • Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon.

    Luisa Cervantes-Barragan;Roland Züst;Friedemann Weber;Martin Spiegel

  • IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

    Marc Pellegrini;Thomas Calzascia;Jesse G. Toe;Simon P. Preston

  • iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.

    David R. McIlwain;Philipp A. Lang;Philipp A. Lang;Thorsten Maretzky;Koichi Hamada

  • Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

    Philipp A. Lang;Karl S. Lang;Haifeng C. Xu;Melanie Grusdat

  • Enhanced Erythrocyte Apoptosis in Sickle Cell Anemia, Thalassemia and Glucose-6-Phosphate Dehydrogenase Deficiency

    Karl S Lang;Benjamin Roll;Svetlana Myssina;Markus Schittenhelm

  • Aggravation of viral hepatitis by platelet-derived serotonin

    Philipp A. Lang;Claudio Contaldo;Panco Georgiev;Ashraf Mohammad El-Badry

  • Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.

    Nadine Honke;Namir Shaabani;Giuseppe Cadeddu;Ursula R Sorg

  • Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.

    Haifeng C. Xu;Haifeng C. Xu;Melanie Grusdat;Aleksandra A. Pandyra;Robin Polz

  • Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

    Karl S. Lang;Mike Recher;Alexander A. Navarini;Nicola L. Harris

  • HLA-A2 Restricted, Melanocyte-Specific CD8+ T Lymphocytes Detected in Vitiligo Patients are Related to Disease Activity and are Predominantly Directed Against MelanA/MART1

    Karl Sebastian Lang;Constanze Charlotte Caroli;Alexandra Muhm;Dorothee Wernet

  • Antigen kinetics determines immune reactivity.

    Pål Johansen;Tazio Storni;Lorna Rettig;Zhiyong Qiu

  • Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

    Karl S. Lang;Panco Georgiev;Mike Recher;Alexander A. Navarini

  • Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

    Max Löhning;Max Löhning;Ahmed N. Hegazy;Daniel D. Pinschewer;Dorothea Busse

  • Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells.

    Alexander Carpinteiro;Michael J. Edwards;Markus Hoffmann;Markus Hoffmann;Georg Kochs

  • Dependence of Plasmodium falciparum in vitro growth on the cation permeability of the human host erythrocyte.

    Verena B Brand;Ciprian D Sandu;Christophe Duranton;Valerie Tanneur

  • Inhibition of Erythrocyte Cation Channels by Erythropoietin

    Svetlana Myssina;Stephan M. Huber;Christina Birka;Philipp A. Lang

  • Conjugated bilirubin triggers anemia by inducing erythrocyte death.

    Elisabeth Lang;Sergios Gatidis;Noemi F. Freise;Hans Bock

  • Cooperative Phagocytes: Resident Microglia and Bone Marrow Immigrants Remove Dead Photoreceptors in Retinal Lesions

    Sandrine Joly;Mike Francke;Elke Ulbricht;Susanne Beck

  • Inactivation of TGFβ signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

    Heiko Wurdak;Lars M. Ittner;Karl S. Lang;Per Leveen

Frequent Co-Authors

Philipp A. Lang
Philipp A. Lang Heinrich Heine University Düsseldorf
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Florian Lang
Florian Lang University of Tübingen
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Stephan M. Huber
Stephan M. Huber University of Tübingen
Rolf M. Zinkernagel
Rolf M. Zinkernagel University of Zurich
Hans Hengartner
Hans Hengartner University of Zurich
Thomas Wieder
Thomas Wieder University of Tübingen
Ulf Dittmer
Ulf Dittmer University of Duisburg-Essen

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