His primary areas of investigation include Cancer research, Notch signaling pathway, Signal transduction, Cancer and Cell biology. Lucio Miele has researched Cancer research in several fields, including Cancer cell, Cancer stem cell, Notch 1 and Multiple myeloma. His Notch signaling pathway study combines topics from a wide range of disciplines, such as Myeloid, Immunology, Thymic stromal lymphopoietin and Stem cell.
His Signal transduction research integrates issues from Alzheimer's disease, Transcription factor and Cellular differentiation. His Cancer research is multidisciplinary, incorporating perspectives in Cell signaling and Pathology. His research integrates issues of Lineage, Genetics and Cytotoxic T cell, MHC class I, Major histocompatibility complex in his study of Cell biology.
His primary areas of study are Cancer research, Notch signaling pathway, Cancer, Breast cancer and Internal medicine. His work deals with themes such as Cancer stem cell, Stem cell, Triple-negative breast cancer and Metastasis, which intersect with Cancer research. The study incorporates disciplines such as Cell signaling and Cellular differentiation in addition to Notch signaling pathway.
Lucio Miele has included themes like Disease, Pathology and Bioinformatics in his Cancer study. His studies in Internal medicine integrate themes in fields like Endocrinology and Oncology. Lucio Miele works mostly in the field of Signal transduction, limiting it down to topics relating to Apoptosis and, in certain cases, Molecular biology.
His scientific interests lie mostly in Cancer research, Breast cancer, Triple-negative breast cancer, Cancer and Metastasis. His Cancer research research incorporates themes from Epithelial–mesenchymal transition, Cancer stem cell, Kinase and Notch signaling pathway. His Notch signaling pathway study deals with the bigger picture of Cell biology.
The various areas that Lucio Miele examines in his Breast cancer study include Precision medicine, Stem cell and Oncology. His Cancer research includes elements of Acquired immune system and Gerontology. His biological study spans a wide range of topics, including Carcinogenesis and Drug resistance.
The scientist’s investigation covers issues in Breast cancer, Ethnic group, Incidence, Cancer research and Mortality rate. Cancer and Internal medicine are the focus of his Breast cancer studies. His Cancer research research integrates issues from Metastasis and Stem cell.
His research on Cancer stem cell often connects related areas such as Notch signaling pathway. While the research belongs to areas of Notch signaling pathway, Lucio Miele spends his time largely on the problem of Psychological repression, intersecting his research to questions surrounding Cell biology. His study of Signal transduction is a part of Cell biology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
Naoko Takebe;Lucio Miele;Pamela Jo Harris;Woondong Jeong.
Nature Reviews Clinical Oncology (2015)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas.
The EMBO Journal (2001)
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.
Sanne Weijzen;Paola Rizzo;Mike Braid;Radhika Vaishnav.
Nature Medicine (2002)
Rational targeting of Notch signaling in cancer.
P Rizzo;C Osipo;K Foreman;T Golde.
Oncogene (2008)
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas;Joaquina Mascarenhas;Teresa Palomero;Malay Mandal.
Nature Medicine (2007)
Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents
Brian J Nickoloff;Barbara A Osborne;Lucio Miele.
Oncogene (2003)
Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ
B J Nickoloff;J-Z Qin;V Chaturvedi;M F Denning.
Cell Death & Differentiation (2002)
Arbiter of differentiation and death: Notch signaling meets apoptosis.
Lucio Miele;Barbara Osborne.
Journal of Cellular Physiology (1999)
Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches
Paola Rizzo;Haixi Miao;Gwendolyn D'Souza;Gwendolyn D'Souza;Clodia Osipo.
Cancer Research (2008)
Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells
Jian Zhong Qin;Jeffrey Ziffra;Lawrence Stennett;Barbara Bodner.
Cancer Research (2005)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
University of Massachusetts Amherst
National Institutes of Health
University of Florida
Eli Lilly (United States)
University of North Texas Health Science Center
Loyola University Chicago
Johns Hopkins University School of Medicine
University of Nottingham
Michigan State University
Moffitt Cancer Center
Institute of Science and Technology Austria
University of Sydney
University of Michigan–Ann Arbor
National University of Comahue
National Museum of Natural History
University of Copenhagen
Purdue University West Lafayette
University of Hyogo
University of Costa Rica
Liverpool School of Tropical Medicine
University of California, Riverside
Earth System Research Laboratory
University of Bern
University of New South Wales
Imperial College London