D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 17,565 208 World Ranking 5498 National Ranking 2639

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Genetics

His primary areas of investigation include Cancer research, Notch signaling pathway, Signal transduction, Cancer and Cell biology. Lucio Miele has researched Cancer research in several fields, including Cancer cell, Cancer stem cell, Notch 1 and Multiple myeloma. His Notch signaling pathway study combines topics from a wide range of disciplines, such as Myeloid, Immunology, Thymic stromal lymphopoietin and Stem cell.

His Signal transduction research integrates issues from Alzheimer's disease, Transcription factor and Cellular differentiation. His Cancer research is multidisciplinary, incorporating perspectives in Cell signaling and Pathology. His research integrates issues of Lineage, Genetics and Cytotoxic T cell, MHC class I, Major histocompatibility complex in his study of Cell biology.

His most cited work include:

  • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation (735 citations)
  • Rational targeting of Notch signaling in cancer. (321 citations)
  • Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches (288 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cancer research, Notch signaling pathway, Cancer, Breast cancer and Internal medicine. His work deals with themes such as Cancer stem cell, Stem cell, Triple-negative breast cancer and Metastasis, which intersect with Cancer research. The study incorporates disciplines such as Cell signaling and Cellular differentiation in addition to Notch signaling pathway.

Lucio Miele has included themes like Disease, Pathology and Bioinformatics in his Cancer study. His studies in Internal medicine integrate themes in fields like Endocrinology and Oncology. Lucio Miele works mostly in the field of Signal transduction, limiting it down to topics relating to Apoptosis and, in certain cases, Molecular biology.

He most often published in these fields:

  • Cancer research (46.77%)
  • Notch signaling pathway (33.06%)
  • Cancer (27.42%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (46.77%)
  • Breast cancer (22.58%)
  • Triple-negative breast cancer (12.90%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cancer research, Breast cancer, Triple-negative breast cancer, Cancer and Metastasis. His Cancer research research incorporates themes from Epithelial–mesenchymal transition, Cancer stem cell, Kinase and Notch signaling pathway. His Notch signaling pathway study deals with the bigger picture of Cell biology.

The various areas that Lucio Miele examines in his Breast cancer study include Precision medicine, Stem cell and Oncology. His Cancer research includes elements of Acquired immune system and Gerontology. His biological study spans a wide range of topics, including Carcinogenesis and Drug resistance.

Between 2017 and 2021, his most popular works were:

  • Health and Racial Disparity in Breast Cancer. (27 citations)
  • Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway. (24 citations)
  • Breast Cancer Stem Cells. (22 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

The scientist’s investigation covers issues in Breast cancer, Ethnic group, Incidence, Cancer research and Mortality rate. Cancer and Internal medicine are the focus of his Breast cancer studies. His Cancer research research integrates issues from Metastasis and Stem cell.

His research on Cancer stem cell often connects related areas such as Notch signaling pathway. While the research belongs to areas of Notch signaling pathway, Lucio Miele spends his time largely on the problem of Psychological repression, intersecting his research to questions surrounding Cell biology. His study of Signal transduction is a part of Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

Naoko Takebe;Lucio Miele;Pamela Jo Harris;Woondong Jeong.
Nature Reviews Clinical Oncology (2015)

1131 Citations

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas.
The EMBO Journal (2001)

1022 Citations

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.

Sanne Weijzen;Paola Rizzo;Mike Braid;Radhika Vaishnav.
Nature Medicine (2002)

725 Citations

Rational targeting of Notch signaling in cancer.

P Rizzo;C Osipo;K Foreman;T Golde.
Oncogene (2008)

444 Citations

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

Tomas Vilimas;Joaquina Mascarenhas;Teresa Palomero;Malay Mandal.
Nature Medicine (2007)

440 Citations

Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

Brian J Nickoloff;Barbara A Osborne;Lucio Miele.
Oncogene (2003)

431 Citations

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ

B J Nickoloff;J-Z Qin;V Chaturvedi;M F Denning.
Cell Death & Differentiation (2002)

423 Citations

Arbiter of differentiation and death: Notch signaling meets apoptosis.

Lucio Miele;Barbara Osborne.
Journal of Cellular Physiology (1999)

422 Citations

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

Paola Rizzo;Haixi Miao;Gwendolyn D'Souza;Gwendolyn D'Souza;Clodia Osipo.
Cancer Research (2008)

402 Citations

Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Jian Zhong Qin;Jeffrey Ziffra;Lawrence Stennett;Barbara Bodner.
Cancer Research (2005)

387 Citations

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