World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
30921
World Ranking
1693
National Ranking
942

Overview

Lucio Miele is affiliated with Louisiana State University Health Sciences Center New Orleans in the United States and has an extensive research profile primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work focuses significantly on Oncology, with key subfields including Molecular Biology, Immunology, Infectious Diseases, and Cancer Research.

The scientist has contributed to studies covering a wide range of main research topics, including:

  • Cancer Cells and Metastasis
  • Cancer Risks and Factors
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Adenosine and Purinergic Signaling
  • Histone Deacetylase Inhibitors Research

Their research output includes publications in frequent venues such as:

  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Frontiers in Immunology

Among recent papers, notable contributions include the following titles with publication year and venue:

  • Targeting Notch in oncology: the path forward, 2020, Nature Reviews Drug Discovery
  • Racial Disparities in Triple Negative Breast Cancer: A Review of the Role of Biologic and Non-biologic Factors, 2020, Frontiers in Public Health
  • Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative, 2021, Journal of the American Medical Informatics Association
  • Precision Medicine and Triple-Negative Breast Cancer: Current Landscape and Future Directions, 2021, Cancers
  • Obesity-Altered Adipose Stem Cells Promote Radiation Resistance of Estrogen Receptor Positive Breast Cancer through Paracrine Signaling, 2020, International Journal of Molecular Sciences

Frequent co-authors in Lucio Miele's research include:

  • Jovanny Zabaleta
  • Fokhrul Hossain
  • Samarpan Majumder
  • Luis Del Valle
  • Ronald Horswell

Best Publications

  • Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

    Naoko Takebe;Lucio Miele;Pamela Jo Harris;Woondong Jeong

  • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

    Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas

  • Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.

    Sanne Weijzen;Paola Rizzo;Mike Braid;Radhika Vaishnav

  • Targeting Notch to target cancer stem cells.

    Antonio Pannuti;Kimberly Foreman;Paola Rizzo;Clodia Osipo

  • Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

    Tomas Vilimas;Joaquina Mascarenhas;Teresa Palomero;Malay Mandal

  • Rational targeting of Notch signaling in cancer.

    P Rizzo;C Osipo;K Foreman;T Golde

  • Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ

    B J Nickoloff;J-Z Qin;V Chaturvedi;M F Denning

  • Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

    Brian J Nickoloff;Barbara A Osborne;Lucio Miele

  • Arbiter of differentiation and death: Notch signaling meets apoptosis.

    Lucio Miele;Barbara Osborne

  • Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

    Paola Rizzo;Haixi Miao;Gwendolyn D'Souza;Gwendolyn D'Souza;Clodia Osipo

  • Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

    Jian Zhong Qin;Jeffrey Ziffra;Lawrence Stennett;Barbara Bodner

  • Retraction notice to “Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells”

    Bin Bao;Zhiwei Wang;Shadan Ali;Dejuan Kong

  • Health and Racial Disparity in Breast Cancer

    Clement G. Yedjou;Jennifer N. Sims;Lucio Miele;Felicite Noubissi

  • Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

    Lisa M Minter;Danielle M Turley;Pritam Das;Hyun Mu Shin

  • The duration of antigen receptor signalling determines CD4 + versus CD8 + T-cell lineage fate

    Koji Yasutomo;Carolyn Doyle;Lucio Miele;Ronald N. Germain

  • γ-Secretase inhibitors and modulators.

    Todd E. Golde;Edward H. Koo;Kevin M. Felsenstein;Barbara A. Osborne

  • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

    Christine L Curry;Laura L Reed;Todd E Golde;Lucio Miele

  • Involvement of Notch signaling in hippocampal synaptic plasticity

    Yue Wang;Sic L. Chan;Lucio Miele;Pamela J. Yao

  • Notch-1 Regulates NF-κB Activity in Hemopoietic Progenitor Cells

    Pingyan Cheng;Andrew Zlobin;Veronica Volgina;Sridevi Gottipati

  • Notch Signaling in Cancer

    Lucio Miele;Todd Golde;Barbara Osborne

Frequent Co-Authors

Barbara A. Osborne
Barbara A. Osborne University of Massachusetts Amherst
Anil B. Mukherjee
Anil B. Mukherjee National Institutes of Health
Todd E. Golde
Todd E. Golde Emory University
Brian J. Nickoloff
Brian J. Nickoloff Loyola University Chicago
Bruce A. Bunnell
Bruce A. Bunnell University of North Texas Health Science Center
Kathy S. Albain
Kathy S. Albain Loyola University Chicago
Michael Hoerger
Michael Hoerger Tulane University
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Paulo C. Rodriguez
Paulo C. Rodriguez Moffitt Cancer Center
Asgerally T. Fazleabas
Asgerally T. Fazleabas Michigan State University

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