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Medicine

D-Index
97
Citations
28548
World Ranking
9422
National Ranking
4856

Overview

Lucio Miele is affiliated with Louisiana State University Health Sciences Center New Orleans in the United States. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, with significant contributions to oncology and molecular biology.

The key subfields of their work include:

  • Oncology
  • Molecular Biology
  • Immunology
  • Infectious Diseases
  • Cancer Research

Among the main topics covered in their research are:

  • Cancer Cells and Metastasis
  • Cancer Risks and Factors
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Adenosine and Purinergic Signaling
  • Histone Deacetylase Inhibitors Research

Their publication record includes numerous papers in notable venues. Frequent publication venues include:

  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Frontiers in Immunology

Recent papers highlight diverse topics in oncology and public health. Selected recent publications include:

  • Targeting Notch in oncology: the path forward, 2020, Nature Reviews Drug Discovery
  • Racial Disparities in Triple Negative Breast Cancer: A Review of the Role of Biologic and Non-biologic Factors, 2020, Frontiers in Public Health
  • Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative, 2021, Journal of the American Medical Informatics Association
  • Precision Medicine and Triple-Negative Breast Cancer: Current Landscape and Future Directions, 2021, Cancers
  • Obesity-Altered Adipose Stem Cells Promote Radiation Resistance of Estrogen Receptor Positive Breast Cancer through Paracrine Signaling, 2020, International Journal of Molecular Sciences

Lucio Miele has collaborated frequently with several researchers. Frequent co-authors include:

  • Jovanny Zabaleta
  • Fokhrul Hossain
  • Samarpan Majumder
  • Luis Del Valle
  • Ronald Horswell

Best Publications

  • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

    Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas

  • Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.

    Sanne Weijzen;Paola Rizzo;Mike Braid;Radhika Vaishnav

  • Targeting Notch to target cancer stem cells.

    Antonio Pannuti;Kimberly Foreman;Paola Rizzo;Clodia Osipo

  • Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

    Tomas Vilimas;Joaquina Mascarenhas;Teresa Palomero;Malay Mandal

  • Rational targeting of Notch signaling in cancer.

    P Rizzo;C Osipo;K Foreman;T Golde

  • Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ

    B J Nickoloff;J-Z Qin;V Chaturvedi;M F Denning

  • Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

    Brian J Nickoloff;Barbara A Osborne;Lucio Miele

  • Arbiter of differentiation and death: Notch signaling meets apoptosis.

    Lucio Miele;Barbara Osborne

  • Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

    Paola Rizzo;Haixi Miao;Gwendolyn D'Souza;Gwendolyn D'Souza;Clodia Osipo

  • Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

    Jian Zhong Qin;Jeffrey Ziffra;Lawrence Stennett;Barbara Bodner

  • Retraction notice to “Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells”

    Bin Bao;Zhiwei Wang;Shadan Ali;Dejuan Kong

  • Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

    Lisa M Minter;Danielle M Turley;Pritam Das;Hyun Mu Shin

  • Notch Inhibitors for Cancer Treatment

    Ingrid Espinoza;Lucio Miele

  • The duration of antigen receptor signalling determines CD4 + versus CD8 + T-cell lineage fate

    Koji Yasutomo;Carolyn Doyle;Lucio Miele;Ronald N. Germain

  • γ-Secretase inhibitors and modulators.

    Todd E. Golde;Edward H. Koo;Kevin M. Felsenstein;Barbara A. Osborne

  • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

    Christine L Curry;Laura L Reed;Todd E Golde;Lucio Miele

  • Involvement of Notch signaling in hippocampal synaptic plasticity

    Yue Wang;Sic L. Chan;Lucio Miele;Pamela J. Yao

  • Notch-1 Regulates NF-κB Activity in Hemopoietic Progenitor Cells

    Pingyan Cheng;Andrew Zlobin;Veronica Volgina;Sridevi Gottipati

  • Notch Signaling in Cancer

    Lucio Miele;Todd Golde;Barbara Osborne

  • TCR-Mediated Notch Signaling Regulates Proliferation and IFN-γ Production in Peripheral T Cells

    Tanapat Palaga;Lucio Miele;Todd E. Golde;Barbara A. Osborne

Frequent Co-Authors

Fazlul H. Sarkar
Fazlul H. Sarkar Wayne State University
Todd E. Golde
Todd E. Golde Emory University
Barbara A. Osborne
Barbara A. Osborne University of Massachusetts Amherst
Zhiwei Wang
Zhiwei Wang Soochow University
Bin Bao
Bin Bao Wayne State University
Sanjeev Banerjee
Sanjeev Banerjee Wayne State University
Yiwei Li
Yiwei Li Wayne State University
Anil B. Mukherjee
Anil B. Mukherjee National Institutes of Health
Antonio Giordano
Antonio Giordano Temple University
Stefano Stifani
Stefano Stifani Montreal Neurological Institute and Hospital

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