D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 58 Citations 19,496 191 World Ranking 1388 National Ranking 709

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Cancer

Her primary areas of study are Notch signaling pathway, Immunology, Cell biology, Programmed cell death and Signal transduction. Her Notch signaling pathway research incorporates themes from Cancer, Stem cell and Cell fate determination. Her work deals with themes such as Receptor, Neuroscience, Outbreak and Pneumonia, which intersect with Immunology.

Her Cell biology study incorporates themes from T cell, T-cell receptor and Transcription factor. Her Programmed cell death research is within the category of Apoptosis. Her work carried out in the field of Apoptosis brings together such families of science as Thymocyte and DNA damage.

Her most cited work include:

  • p53 is required for radiation-induced apoptosis in mouse thymocytes (2599 citations)
  • Efficacy and Safety of Fluconazole Prophylaxis for Fungal Infections after Marrow Transplantation—A Prospective, Randomized, Double-Blind Study (731 citations)
  • Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. (519 citations)

What are the main themes of her work throughout her whole career to date?

Cell biology, Notch signaling pathway, Immunology, Molecular biology and Apoptosis are her primary areas of study. Her research in Cell biology intersects with topics in Cell culture, Cellular differentiation and T cell, Immune system, T-cell receptor. Her Notch signaling pathway study combines topics from a wide range of disciplines, such as Cancer research and Protein kinase B.

Her Immunology research is multidisciplinary, relying on both Haematopoiesis and Stem cell. She studies Programmed cell death which is a part of Apoptosis. Her Programmed cell death study combines topics in areas such as Thymocyte and Gene.

She most often published in these fields:

  • Cell biology (44.66%)
  • Notch signaling pathway (26.21%)
  • Immunology (22.82%)

What were the highlights of her more recent work (between 2015-2021)?

  • Cancer research (16.02%)
  • Cell biology (44.66%)
  • Notch signaling pathway (26.21%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Cancer research, Cell biology, Notch signaling pathway, Triple-negative breast cancer and Immunotherapy. The Cancer research study combines topics in areas such as Mesenchymal stem cell, Cancer, Cancer stem cell and Hematopoietic stem cell transplantation. Barbara A. Osborne interconnects T cell, Cell culture, Cellular differentiation and FOXP3 in the investigation of issues within Cell biology.

Her Notch signaling pathway research integrates issues from Cell, Protein kinase B, Regulatory macrophages, Cytokine and NF-κB. Antibody is the subject of her research, which falls under Immunology. Her biological study spans a wide range of topics, including Carcinogenesis, Apoptosis, Targeted therapy and Proteasome.

Between 2015 and 2021, her most popular works were:

  • γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct (70 citations)
  • Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. (32 citations)
  • Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways. (29 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

Barbara A. Osborne mostly deals with Cell biology, Cancer research, Immune system, Notch signaling pathway and Antibody. The study incorporates disciplines such as Receptor, Cellular differentiation and T-cell receptor in addition to Cell biology. Her Immune system research includes themes of Cell culture, Psychological repression, In vitro and Cytokine.

Her study in Notch signaling pathway is interdisciplinary in nature, drawing from both Tumor microenvironment, Cancer stem cell, NF-κB, Transcription and Cancer immunology. Antibody is a subfield of Immunology that Barbara A. Osborne studies. Her work on Superantigen is typically connected to Arginase as part of general Immunology study, connecting several disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

p53 is required for radiation-induced apoptosis in mouse thymocytes

Scott W. Lowe;Earlene M. Schmitt;Sallie W. Smith;Barbara A. Osborne.
Nature (1993)

3891 Citations

Efficacy and Safety of Fluconazole Prophylaxis for Fungal Infections after Marrow Transplantation—A Prospective, Randomized, Double-Blind Study

M A Slavin;B Osborne;R Adams;M J Levenstein.
The Journal of Infectious Diseases (1995)

995 Citations

Do all programmed cell deaths occur via apoptosis

Lawrence M. Schwartz;Sallie W. Smith;Margaret E. E. Jones;Barbara A. Osborne.
Proceedings of the National Academy of Sciences of the United States of America (1993)

746 Citations

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.

Sanne Weijzen;Paola Rizzo;Mike Braid;Radhika Vaishnav.
Nature Medicine (2002)

725 Citations

Apoptotic Signals Delivered Through the T-Cell Receptor of a T-Cell Hybrid Require the Immediate-Early Gene Nur77

Zheng-Gang Liu;Sallie W. Smith;Kelly A. McLaughlin;Lawrence M. Schwartz.
Nature (1994)

663 Citations

Programmed cell death, apoptosis and killer genes

Lawrence M. Schwartz;Barbara A. Osborne.
Immunology Today (1993)

564 Citations

Targeting Notch to target cancer stem cells.

Antonio Pannuti;Kimberly Foreman;Paola Rizzo;Clodia Osipo.
Clinical Cancer Research (2010)

494 Citations

An Outbreak of Respiratory Syncytial Virus in a Bone Marrow Transplant Center

Robert D. Harrington;Thomas M. Hooton;Thomas M. Hooton;Robert C. Hackman;Robert C. Hackman;Gregory A. Storch;Gregory A. Storch.
The Journal of Infectious Diseases (1992)

490 Citations

Rational targeting of Notch signaling in cancer.

P Rizzo;C Osipo;K Foreman;T Golde.
Oncogene (2008)

444 Citations

Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents

Brian J Nickoloff;Barbara A Osborne;Lucio Miele.
Oncogene (2003)

431 Citations

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