What is he best known for?
The fields of study he is best known for:
Warren S. Pear mainly focuses on Notch signaling pathway, Cell biology, Signal transduction, Immunology and T cell.
He studied Notch signaling pathway and Stem cell that intersect with Adult stem cell.
His Cell biology research focuses on Progenitor cell in particular.
In his research, Molecular biology, Notch Family and Hairless is intimately related to Transcription factor, which falls under the overarching field of Signal transduction.
His research is interdisciplinary, bridging the disciplines of Cancer research and Immunology.
His work deals with themes such as Apoptosis and Leukemia, which intersect with T cell.
His most cited work include:
- Production of high titer helper-free retroviruses by transient transfection (2529 citations)
- Notch1 expression in early lymphopoiesis influences B versus T lineage determination. (877 citations)
- c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma (713 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Notch signaling pathway, Cell biology, Cancer research, T cell and Immunology.
The Notch signaling pathway portion of his research involves studies in Signal transduction and Receptor.
His Cell biology research is multidisciplinary, incorporating perspectives in Transcription factor and Cellular differentiation.
His Cancer research study incorporates themes from breakpoint cluster region, Carcinogenesis, Mutation, Leukemia and Bone marrow.
His T cell research includes elements of B cell, Cell fate determination and Lymphoma.
His Immunology research includes themes of Cell, Lineage, Oncogene and Transgene.
He most often published in these fields:
- Notch signaling pathway (46.32%)
- Cell biology (47.19%)
- Cancer research (37.23%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (47.19%)
- Notch signaling pathway (46.32%)
- Cancer research (37.23%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Notch signaling pathway, Cancer research, Transcription factor and T cell.
His study in the field of Progenitor cell, Stem cell and Regeneration is also linked to topics like Population.
In his study, HES1 and PCAF is inextricably linked to Leukemia, which falls within the broad field of Notch signaling pathway.
He combines subjects such as Carcinogenesis, Chronic lymphocytic leukemia, B cell and MAPK/ERK pathway with his study of Cancer research.
Warren S. Pear interconnects Chromatin, Regulation of gene expression and Cytokine in the investigation of issues within Transcription factor.
His T cell study introduces a deeper knowledge of Immunology.
Between 2014 and 2021, his most popular works were:
- Regeneration of fat cells from myofibroblasts during wound healing (221 citations)
- The Varied Roles of Notch in Cancer. (211 citations)
- Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds. (113 citations)
In his most recent research, the most cited papers focused on:
Warren S. Pear spends much of his time researching Cell biology, Transcription factor, Notch signaling pathway, Chromatin and T cell.
His work on Regeneration and Signal transduction as part of general Cell biology study is frequently linked to Myofibroblast, therefore connecting diverse disciplines of science.
His studies in Transcription factor integrate themes in fields like Regulation of gene expression and Cytokine.
His research integrates issues of Carcinogenesis, Cancer research and Gene rearrangement in his study of Notch signaling pathway.
The various areas that Warren S. Pear examines in his Cancer research study include Regulome, B-cell receptor, B cell, Oncogene MYC and Chronic lymphocytic leukemia.
The concepts of his Chromatin study are interwoven with issues in Reprogramming, Cell signaling, Epigenetics and RBPJ.
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