His primary areas of investigation include Cell biology, Wnt signaling pathway, Signal transduction, Notch signaling pathway and Cancer research. His work deals with themes such as Endothelial stem cell, Genetics, Angiogenesis, Cellular differentiation and Autocrine signalling, which intersect with Cell biology. His Wnt signaling pathway research includes themes of RNA interference and Metastasis.
His Signal transduction research integrates issues from Phenotype, Regulation of gene expression and Transcription factor. His Notch signaling pathway research is multidisciplinary, incorporating perspectives in Molecular biology and Mutant. The study incorporates disciplines such as Apoptosis, Programmed cell death, Lung cancer, LGR5 and Adenocarcinoma in addition to Cancer research.
Jan Kitajewski mostly deals with Cell biology, Notch signaling pathway, Angiogenesis, Cancer research and Internal medicine. His work carried out in the field of Cell biology brings together such families of science as Endothelial stem cell, Transcription factor and Cellular differentiation. His Notch signaling pathway study incorporates themes from Immunology, Cell fate determination and Pathology.
His study looks at the intersection of Angiogenesis and topics like Corpus luteum with Luteal phase. His Cancer research research incorporates elements of Cancer, Ovarian cancer, Metastasis, Apoptosis and Hemangioma. He focuses mostly in the field of Internal medicine, narrowing it down to topics relating to Endocrinology and, in certain cases, Vascular endothelial growth factor and Stem cell.
His main research concerns Cell biology, Cancer research, Internal medicine, Notch signaling pathway and Angiogenesis. The various areas that he examines in his Cell biology study include Endothelial stem cell, Placenta, Transcription factor and Paracrine signalling. Jan Kitajewski has included themes like Cancer, Ovarian cancer, Pancreatic cancer, Immunology and Hemangioma in his Cancer research study.
His Internal medicine course of study focuses on Endocrinology and Stem cell and Andrology. Jan Kitajewski is investigating Notch signaling pathway as part of his inquiry into Signal transduction and Receptor. His Angiogenesis study combines topics from a wide range of disciplines, such as Corpus luteum, Stromal cell, Luteal phase and Vascular endothelial growth factor.
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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
Andrew D. Rhim;Andrew D. Rhim;Paul E. Oberstein;Dafydd H. Thomas;Emily T. Mirek.
Cancer Cell (2014)
Notch signaling is essential for vascular morphogenesis in mice.
Luke T. Krebs;Yingzi Xue;Christine R. Norton;John R. Shutter.
Genes & Development (2000)
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
Jason M. Butler;Daniel J. Nolan;Eva L. Vertes;Barbara Varnum-Finney.
Cell Stem Cell (2010)
Transformation by Wnt family proteins correlates with regulation of beta-catenin.
Hiroyuki Shimizu;Martin A. Julius;Marianna Giarré;Zhili Zheng.
Cell Growth & Differentiation (1997)
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
Hendrik Uyttendaele;Giovanna Marazzi;Guangyu Wu;Qingyou Yan.
WNT-1 Signaling Inhibits Apoptosis by Activating β-Catenin/T Cell Factor–Mediated Transcription
Shaoqiong Chen;Denis C Guttridge;Zongbing You;Zhaochen Zhang.
Journal of Cell Biology (2001)
Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia
Michael Quante;Michael Quante;Govind Bhagat;Julian A. Abrams;Frederic Marache.
Cancer Cell (2012)
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism.
Axelle Cadoret;Christine Ovejero;Benoit Terris;Evelyne Souil.
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a.
Gonçalo Castelo-Branco;Joseph Wagner;Francisco J. Rodriguez;Julianna Kele.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
Qinghua Zeng;Shenglin Li;Douglas B. Chepeha;Thomas J. Giordano.
Cancer Cell (2005)
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