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D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
27541
World Ranking
2705
National Ranking
1404

Overview

Jan Kitajewski is affiliated with Columbia University in the United States, contributing extensively to research in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several key subfields, including Molecular Biology, Oncology, Cancer Research, Neurology, and Cell Biology.

The scientist's research topics cover a diverse range of subjects such as Angiogenesis and VEGF in Cancer, Developmental Biology and Gene Regulation, Cancer Cells and Metastasis, Cancer-related molecular mechanisms, Epigenetics and DNA Methylation, Congenital heart defects research, and the Lymphatic System and Diseases.

They have authored multiple papers published in notable scientific journals. Recent papers include:

  • Release of stem cells from quiescence reveals gliogenic domains in the adult mouse brain, 2021, Science
  • Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model, 2020, PLoS ONE
  • Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking, 2021, Angiogenesis
  • Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration, 2022, Scientific Reports
  • Unique functions for Notch4 in murine embryonic lymphangiogenesis, 2021, Angiogenesis

Their frequent co-authors include:

  • L.A. Naiche
  • Bhairavi Swaminathan
  • Seock-Won Youn
  • Jason W.-L. Eng
  • Carrie J. Shawber

Jan Kitajewski's work has been published extensively in several venues with repeated contributions, such as:

  • Cancer Research
  • Angiogenesis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research Communications
  • Scientific Reports

Best Publications

  • Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

    Andrew D. Rhim;Andrew D. Rhim;Paul E. Oberstein;Dafydd H. Thomas;Emily T. Mirek

  • Notch signaling is essential for vascular morphogenesis in mice.

    Luke T. Krebs;Yingzi Xue;Christine R. Norton;John R. Shutter

  • Dll4, a novel Notch ligand expressed in arterial endothelium

    John R. Shutter;Sheila Scully;Wei Fan;William G. Richards

  • Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

    Jason M. Butler;Daniel J. Nolan;Eva L. Vertes;Barbara Varnum-Finney

  • Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

    A E Münsterberg;J Kitajewski;D A Bumcrot;A P McMahon

  • Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

    Hendrik Uyttendaele;Giovanna Marazzi;Guangyu Wu;Qingyou Yan

  • Transformation by Wnt family proteins correlates with regulation of beta-catenin.

    Hiroyuki Shimizu;Martin A. Julius;Marianna Giarré;Zhili Zheng

  • Consensus guidelines for the use and interpretation of angiogenesis assays

    Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  • Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia

    Michael Quante;Michael Quante;Govind Bhagat;Julian A. Abrams;Frederic Marache

  • WNT-1 Signaling Inhibits Apoptosis by Activating β-Catenin/T Cell Factor–Mediated Transcription

    Shaoqiong Chen;Denis C Guttridge;Zongbing You;Zhaochen Zhang

  • Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.

    Haixia Xu;Jimmy Zhu;Sinead Smith;Julia Foldi

  • Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

    Jan Kitajewski;Robert J. Schneider;Brian Safer;Susan M. Munemitsu

  • Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

    Bach Cuc Nguyen;Karine Lefort;Anna Mandinova;Dario Antonini

  • New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism.

    Axelle Cadoret;Christine Ovejero;Benoit Terris;Evelyne Souil

  • Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a.

    Gonçalo Castelo-Branco;Joseph Wagner;Francisco J. Rodriguez;Julianna Kele

  • SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation

    Guangyu Wu;Svetlana Lyapina;Indranil Das;Jinhe Li

  • Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling

    Qinghua Zeng;Shenglin Li;Douglas B. Chepeha;Thomas J. Giordano

  • Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

    H. Uyttendaele;J. Ho;J. Rossant;J. Kitajewski

  • Notch signaling regulates tumor angiogenesis by diverse mechanisms

    J. Dufraine;Y. Funahashi;Jan Kitajewski

  • A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

    Tadahiro Kitamura;Tadahiro Kitamura;Yukari Ido Kitamura;Yasuhiro Funahashi;Carrie J. Shawber

Frequent Co-Authors

Ronald J. Wapner
Ronald J. Wapner Columbia University
Jason D. Wright
Jason D. Wright Columbia University
Thomas J. Herzog
Thomas J. Herzog University of Cincinnati
Cande V. Ananth
Cande V. Ananth Rutgers, The State University of New Jersey
Peter Bohlen
Peter Bohlen Eli Lilly (United States)
Domenico Accili
Domenico Accili Columbia University
Anthony M. C. Brown
Anthony M. C. Brown Cornell University
Lionel B. Ivashkiv
Lionel B. Ivashkiv Hospital for Special Surgery
Cun-Yu Wang
Cun-Yu Wang University of California, Los Angeles
Shahin Rafii
Shahin Rafii Cornell University

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