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Neuroscience
Brazil
2023

D-Index & Metrics

Neuroscience

D-Index
65
Citations
13518
World Ranking
3146
National Ranking
270

Research.com Recognitions

  • 2023 - Research.com Neuroscience in Brazil Leader Award
  • 2022 - Research.com Neuroscience in Brazil Leader Award

Overview

Helmut Heinsen is affiliated with the Universidade de São Paulo in Brazil and has a research focus primarily in the fields of Medicine and Neuroscience. Their work spans multiple subfields, including Neurology, Physiology, Cellular and Molecular Neuroscience, Radiology, Nuclear Medicine and Imaging, and Cognitive Neuroscience.

Heinsen's research topics encompass a variety of areas related to neurodegenerative diseases and brain function. The main topics include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Advanced Neuroimaging Techniques and Applications
  • Parkinson's Disease Mechanisms and Treatments
  • Cell Image Analysis Techniques
  • Functional Brain Connectivity Studies
  • Cerebrospinal fluid and hydrocephalus

Their recent publications reflect this wide range of interests, featuring papers such as:

  • "Molecular characterization of selectively vulnerable neurons in Alzheimer's disease" (2021, Nature Neuroscience)
  • "Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging" (2022, Acta Neuropathologica)
  • "Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases" (2022, JAMA Neurology)
  • "Molecular characterization of selectively vulnerable neurons in Alzheimer's Disease" (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • "Deep learning for Alzheimer's disease: Mapping large-scale histological tau protein for neuroimaging biomarker validation" (2021, NeuroImage)

Heinsen frequently publishes in venues such as:

  • Alzheimer s & Dementia
  • Acta Neuropathologica
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Rechtsmedizin
  • Forensic Science Medicine and Pathology

Collaboration is a notable aspect of Heinsen's work. Their frequent co-authors include:

  • Lea T. Grinberg (16 joint publications)
  • William W. Seeley (8 joint publications)
  • Salvatore Spina (8 joint publications)
  • Simone Bohnert (7 joint publications)
  • Michael Bohnert (7 joint publications)

The research output spans several years and demonstrates a concentrated effort on understanding neurodegenerative disorders, emphasizing molecular and cellular characterization, imaging techniques, and potential biomarkers. This multidimensional approach aligns well with emerging trends in neuroscience focusing on integrated disease models and novel diagnostic tools.

Best Publications

  • Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain.

    E. Sofic;P. Riederer;H. Heinsen;H. Beckmann

  • Minicolumnar abnormalities in autism

    Manuel F. Casanova;Imke A. J. van Kooten;Imke A. J. van Kooten;Andrew E. Switala;Herman van Engeland

  • Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery

    Panos Theofilas;Alexander J. Ehrenberg;Sara Dunlop;Ana T. Di Lorenzo Alho

  • Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease

    Kun Leng;Emmy Li;Rana Eser;Antonia Piergies

  • Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

    Matthew J Betts;Matthew J Betts;Evgeniya Kirilina;Evgeniya Kirilina;Maria C G Otaduy;Dimo Ivanov

  • Neurons in the fusiform gyrus are fewer and smaller in autism

    Imke A. J. van Kooten;Saskia J. M. C. Palmen;Patricia von Cappeln;Harry W. M. Steinbusch

  • Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease

    Michel Grothe;Helmut Heinsen;Stefan J. Teipel

  • The Brainstem Pathologies of Parkinson's Disease and Dementia with Lewy Bodies

    Kay Seidel;Josefine Mahlke;Sonny Siswanto;Reijko Krüger

  • Measurement of basal forebrain atrophy in Alzheimer's disease using MRI

    Stefan J. Teipel;Wilhelm H. Flatz;Helmut Heinsen;Arun L. W. Bokde

  • The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

    L. T. Grinberg;U. Rub;R. E. L. Ferretti;R. Nitrini

  • Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study.

    Ingo Kilimann;Michel Grothe;Helmut Heinsen;Eduardo Joaquim Lopez Alho

  • Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease.

    A J Ehrenberg;A J Ehrenberg;A K Nguy;A K Nguy;P Theofilas;S Dunlop

  • Hippocampal neuron number in schizophrenia. A stereological study.

    Stephan Heckers;Helmut Heinsen;Birgit Geiger;Helmut Beckmann

  • Volume, neuron density and total neuron number in five subcortical regions in schizophrenia

    Pawel Kreczmanski;Helmut Heinsen;Valentina Mantua;Fritz Woltersdorf

  • Cortical and striatal neurone number in Huntington's disease

    Heinsen H;Strik M;Bauer M;Luther K

  • Huntington's disease (HD): the neuropathology of a multisystem neurodegenerative disorder of the human brain.

    U. Rüb;K. Seidel;H. Heinsen;J.P. Vonsattel

  • Brainstem pathology and non-motor symptoms in PD.

    Lea Tenenholz Grinberg;Lea Tenenholz Grinberg;Udo Rueb;Ana Tereza di Lorenzo Alho;Helmut Heinsen

  • Cortex, white matter, and basal ganglia in schizophrenia: A volumetric postmortem study

    S. Heckers;H. Heinsen;Y. Heinsen;H. Beckmann

  • Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology.

    Katharina Stratmann;Helmut Heinsen;Horst-Werner Korf;Domenico Del Turco

  • Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease.

    Michel Grothe;Helmut Heinsen;Stefan Teipel;Stefan Teipel

  • Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease

    Kun Leng;Emmy Li;Rana Eser;Antonia Piergies

Frequent Co-Authors

Udo Rüb
Udo Rüb Goethe University Frankfurt
Michel J. Grothe
Michel J. Grothe Institute of Biomedicine of Seville
Horst-Werner Korf
Horst-Werner Korf Goethe University Frankfurt
Stefan J. Teipel
Stefan J. Teipel German Center for Neurodegenerative Diseases
Edson Amaro
Edson Amaro Universidade de São Paulo
Christoph Schmitz
Christoph Schmitz Maastricht University
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Harry W.M. Steinbusch
Harry W.M. Steinbusch Maastricht University
Stephan Heckers
Stephan Heckers Vanderbilt University Medical Center
Andreas Fellgiebel
Andreas Fellgiebel Johannes Gutenberg University of Mainz

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