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Neuroscience
USA
2026

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Neuroscience

D-Index
161
Citations
103427
World Ranking
110
National Ranking
71

Research.com Recognitions

  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award

Overview

Patrick R. Hof is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research focuses broadly within neuroscience, medicine, and biochemistry, genetics, and molecular biology, with significant attention to subfields such as cognitive neuroscience, neurology, molecular biology, cellular and molecular neuroscience, and physiology.

Their work addresses several main topics including Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, neuroscience and neuropharmacology research, memory and neural mechanisms, neural dynamics and brain function, as well as traumatic brain injury and neurovascular disturbances.

Patrick R. Hof has contributed to the scientific literature through publications in several notable venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Comparative Neurology, Alzheimer's & Dementia, Cerebral Cortex, and the Journal of Neuropathology & Experimental Neurology.

Some recent papers associated with or relevant to their research interests include:

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse (2021) in Nature
  • Understanding Emotions: Origins and Roles of the Amygdala (2021) in Biomolecules
  • Molecular and cellular evolution of the primate dorsolateral prefrontal cortex (2022) in Science
  • Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis (2020) in Neuron
  • Transcriptomic cytoarchitecture reveals principles of human neocortex organization (2023) in Science

Their frequent collaborators include:

  • Chet C. Sherwood
  • Merina Varghese (23 co-authored works)
  • Goran Šimić (18 co-authored works)
  • Irene Costantini (18 co-authored works)
  • Rita De Gasperi (17 co-authored works)

Best Publications

  • An anatomically comprehensive atlas of the adult human brain transcriptome

    Michael J. Hawrylycz;Ed S. Lein;Angela L. Guillozet-Bongaarts;Elaine H. Shen

  • Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

    Luc Buée;Thierry Bussière;Valérie Buée-Scherrer;André Delacourte

  • Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

    Peter T Nelson;Irina Alafuzoff;Eileen H Bigio;Constantin Bouras

  • Life and Death of Neurons in the Aging Brain

    John H. Morrison;Patrick R. Hof

  • Primary age-related tauopathy (PART): a common pathology associated with human aging

    John F. Crary;John Q. Trojanowski;Julie A. Schneider;Jose F. Abisambra

  • Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease.

    Panteleimon Giannakopoulos;François Herrmann;T. Bussiere;T. Bussiere;Constantin Bouras;Constantin Bouras

  • Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

    Michael J. Gandal;Pan Zhang;Evi Hadjimichael;Rebecca L. Walker

  • The anterior cingulate cortex. The evolution of an interface between emotion and cognition.

    John M. Allman;Atiya Hakeem;Joseph M. Erwin;Esther Nimchinsky

  • Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting

    Conor Liston;Melinda M. Miller;Deena S. Goldwater;Jason J. Radley

  • Human cingulate cortex: Surface features, flat maps, and cytoarchitecture

    Brent A. Vogt;Esther A. Nimchinsky;Leslie J. Vogt;Patrick R. Hof

  • White matter changes in schizophrenia: evidence for myelin-related dysfunction.

    Kenneth L. Davis;Daniel G. Stewart;Joseph I. Friedman;Monte Buchsbaum

  • Design-based stereology in neuroscience.

    C. Schmitz;P.R. Hof

  • Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex

    Jason J. Radley;Anne B. Rocher;Melinda Miller;William G.M. Janssen

  • New insights into the classification and nomenclature of cortical GABAergic interneurons

    Javier DeFelipe;Pedro L. López-Cruz;Ruth Benavides-Piccione;Ruth Benavides-Piccione;Concha Bielza

  • Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex

    J. J. Radley;J. J. Radley;H. M. Sisti;J. Hao;A. B. Rocher

  • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

    Michael E. Ripps;George W. Huntley;Patrick R. Hof;John H. Morrison

  • Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus.

    Kara Pham;Juan Nacher;Juan Nacher;Patrick R. Hof;Bruce S. McEwen

  • Anterior Insular Cortex and Emotional Awareness

    Xiaosi Gu;Xiaosi Gu;Patrick R. Hof;Karl J. Friston;Jin Fan

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Trygve E. Bakken;Nikolas L. Jorstad;Qiwen Hu;Blue B. Lake

  • Prolonged myelination in human neocortical evolution

    Daniel J. Miller;Tetyana Duka;Cheryl D. Stimpson;Steven J. Schapiro

  • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer’s disease

    Lap Ho;Weiping Qin;Patrick N. Pompl;Zhongmin Xiang

  • Neocortical Neurofibrillary Tangles Correlate With Dementia Severity in Alzheimer's Disease

    Linda M. Bierer;Patrick R. Hof;Dushyant P. Purohit;Linda Carlin

Frequent Co-Authors

Chet C. Sherwood
Chet C. Sherwood George Washington University
John H. Morrison
John H. Morrison University of California, Davis
Constantin Bouras
Constantin Bouras University of Geneva
Dara L. Dickstein
Dara L. Dickstein Uniformed Services University of the Health Sciences
William D. Hopkins
William D. Hopkins University of Wisconsin–Madison
Gregory A. Elder
Gregory A. Elder Icahn School of Medicine at Mount Sinai
William G.M. Janssen
William G.M. Janssen Icahn School of Medicine at Mount Sinai
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai
Susan L. Wearne
Susan L. Wearne Icahn School of Medicine at Mount Sinai
Jin Fan
Jin Fan City University of New York

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