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Neuroscience

D-Index
59
Citations
13110
World Ranking
3993
National Ranking
1816

Overview

William G.M. Janssen is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Neuroscience and Medicine, with a substantial focus on subfields such as Cognitive Neuroscience, Neurology, Molecular Biology, Behavioral Neuroscience, and Developmental Neuroscience.

The main topics of Janssen's research include Memory and Neural Mechanisms, Neuroinflammation and Neurodegeneration Mechanisms, Stress Responses and Cortisol, Traumatic Brain Injury and Neurovascular Disturbances, Functional Brain Connectivity Studies, Traumatic Brain Injury Research, and Autism Spectrum Disorder Research.

Frequent co-authorship collaborations feature several researchers, notably Patrick R. Hof, Allison Sowa, Merina Varghese, John F. Crary, and Miguel A. Gama Sosa.

Janssen has published extensively across various venues, with notable frequency in bioRxiv (Cold Spring Harbor Laboratory), Research Square (Research Square), Acta Neuropathologica Communications, PubMed, and Nature.

Recent significant papers authored or co-authored by Janssen include:

  • Circulating myeloid-derived MMP8 in stress susceptibility and depression, 2024, Nature
  • A novel tau-based rhesus monkey model of Alzheimer's pathogenesis, 2021, Alzheimer s & Dementia
  • The diabetic microenvironment causes mitochondrial oxidative stress in glomerular endothelial cells and pathological crosstalk with podocytes, 2020, Cell Communication and Signaling
  • Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation, 2021, Acta Neuropathologica Communications
  • Altered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats, 2020, Molecular Autism

Best Publications

  • Social stress induces neurovascular pathology promoting depression.

    Caroline Menard;Caroline Menard;Madeline L. Pfau;Georgia E. Hodes;Veronika Kana

  • Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex

    Jason J. Radley;Anne B. Rocher;Melinda Miller;William G.M. Janssen

  • Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons

    Yasushi Hojo;Taka-aki Hattori;Taihei Enami;Aizo Furukawa

  • Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment.

    Dani Dumitriu;Jiandong Hao;Jiandong Hao;Yuko Hara;Jeffrey Kaufmann

  • Estrogen and Aging Affect the Subcellular Distribution of Estrogen Receptor-α in the Hippocampus of Female Rats

    Michelle M. Adams;Susan E. Fink;Ravi A. Shah;William G. M. Janssen

  • Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus.

    S. J. Siegel;N. Brose;W. G. Janssen;G. P. Gasic

  • Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress.

    Jason J Radley;Anne B Rocher;William G M Janssen;Patrick R Hof;Patrick R Hof

  • Different modes of hippocampal plasticity in response to estrogen in young and aged female rats.

    Michelle M. Adams;Ravi A. Shah;William G. M. Janssen;John H. Morrison

  • IκB Kinase Regulates Social Defeat Stress-Induced Synaptic and Behavioral Plasticity

    Daniel J. Christoffel;Sam A. Golden;Dani Dumitriu;Alfred J. Robison

  • Estrogen increases the number of spinophilin‐immunoreactive spines in the hippocampus of young and aged female rhesus monkeys

    Jiandong Hao;William G.M. Janssen;Yong Tang;Jeffrey A. Roberts

  • Estrogen alters spine number and morphology in prefrontal cortex of aged female rhesus monkeys.

    Jiandong Hao;Peter R. Rapp;Abba E. Leffler;Shoshana R. Leffler

  • Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment

    Yuko Hara;Frank Yuk;Rishi Puri;William G. M. Janssen

  • Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons.

    Hideo Mukai;Tomokazu Tsurugizawa;Gen Murakami;Shiro Kominami

  • Evidence for Reduced Experience-Dependent Dendritic Spine Plasticity in the Aging Prefrontal Cortex

    Erik B. Bloss;William G. Janssen;Daniel T. Ohm;Frank J. Yuk

  • Interactive effects of age and estrogen on cognition and pyramidal neurons in monkey prefrontal cortex

    Jiandong Hao;Peter R. Rapp;William G. M. Janssen;Wendy Lou

  • Expression of Dopamine D3 Receptor Dimers and Tetramers in Brain and in Transfected Cells

    Esther A. Nimchinsky;Patrick R. Hof;William G.M. Janssen;John H. Morrison

  • Estrogen Replacement Increases Spinophilin-immunoreactive Spine Number in the Prefrontal Cortex of Female Rhesus Monkeys

    Yong Tang;William G.M. Janssen;Jiandong Hao;Jeffrey A. Roberts

  • Interactive effects of stress and aging on structural plasticity in the prefrontal cortex

    Erik B. Bloss;William G. Janssen;Bruce S. McEwen;John H. Morrison

  • Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus.

    Yong He;William G.M. Janssen;Jeffrey D. Rothstein;John H. Morrison

  • Estrogen modulates synaptic N‐methyl‐D‐aspartate receptor subunit distribution in the aged hippocampus

    Michelle M. Adams;Susan E. Fink;William G.M. Janssen;Ravi A. Shah

Frequent Co-Authors

John H. Morrison
John H. Morrison University of California, Davis
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Bruce S. McEwen
Bruce S. McEwen Rockefeller University
Peter R. Rapp
Peter R. Rapp National Institutes of Health
Dara L. Dickstein
Dara L. Dickstein Uniformed Services University of the Health Sciences
Gregory A. Elder
Gregory A. Elder Icahn School of Medicine at Mount Sinai
Teresa A. Milner
Teresa A. Milner Cornell University
Suguru Kawato
Suguru Kawato University of Tokyo
Andrea C. Gore
Andrea C. Gore The University of Texas at Austin
Joseph E. LeDoux
Joseph E. LeDoux New York University

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