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Gabriele M. Rune

Gabriele M. Rune

D-Index & Metrics

Neuroscience

D-Index
41
Citations
7623
World Ranking
7807
National Ranking
654

Overview

Gabriele M. Rune is affiliated with Universität Hamburg in Germany and has contributed extensively to the fields of neuroscience, biochemistry, genetics, molecular biology, and medicine. Their research primarily explores the complex interplay between hormones and brain function, with a particular focus on estrogen and related hormone effects.

Their work is grounded in several subfields including genetics, cellular and molecular neuroscience, behavioral neuroscience, endocrinology, diabetes and metabolism, and reproductive medicine. Within these areas, their main topics of research cover:

  • Estrogen and related hormone effects
  • Neuroscience and neuropharmacology research
  • Stress responses and cortisol
  • Menopause: health impacts and treatments
  • Hypothalamic control of reproductive hormones
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroendocrine regulation and behavior

Gabriele M. Rune has published in various journals, contributing multiple articles to outlets such as:

  • Journal of Neuroendocrinology
  • Psychoneuroendocrinology
  • Neuroscience Letters
  • Scientific Reports
  • Vitamins and hormones

Selected recent papers include:

  • "Sex neurosteroids: Hormones made by the brain for the brain" (2021, Neuroscience Letters)
  • "Sex-specific features of spine densities in the hippocampus" (2020, Scientific Reports)
  • "Neural sex steroids and hippocampal synaptic plasticity" (2020, Vitamins and hormones)
  • "GPER1 Signaling Initiates Migration of Female V-SVZ-Derived Cells" (2020, iScience)
  • "GPER1 deficiency causes sex-specific dysregulation of hippocampal plasticity and cognitive function" (2023, Journal of Endocrinology)

Their frequent collaborators include Bianka Brunne, Lars Fester, Nicola Brandt, Roland A. Bender, and Gina Joue, with multiple joint publications reinforcing ongoing partnerships in neuroscience research.

Best Publications

  • Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection

    Robert S. Jack;Xiaolong Fan;Martin Bernheiden;Gabriele Rune

  • Hippocampal Synapses Depend on Hippocampal Estrogen Synthesis

    Oliver Kretz;Lars Fester;Uwe Wehrenberg;Lepu Zhou

  • The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

    Maria-Magdalena Mocanu;Astrid Nissen;Katrin Eckermann;Inna Khlistunova

  • The dissection course – necessary and indispensable for teaching anatomy to medical students

    Horst-Werner Korf;Helmut Wicht;Robert L. Snipes;Jean-Pierre Timmermans

  • Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

    Astrid Sydow;Anneke Van der Jeugd;Fang Zheng;Tariq Ahmed

  • Para/autocrine regulation of estrogen receptors in hippocampal neurons.

    Janine Prange-Kiel;Uwe Wehrenberg;Hubertus Jarry;Gabriele M. Rune

  • Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy.

    Nicola M. Tomas;Elion Hoxha;Anna T. Reinicke;Lars Fester

  • Aromatase Inhibition Abolishes LTP Generation in Female But Not in Male Mice

    Ricardo Vierk;Günter Glassmeier;Lepu Zhou;Nicola Brandt

  • The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy

    Katrin Eckermann;Maria Magdalena Mocanu;Inna Khlistunova;Jacek Biernat

  • Aromatase Inhibitors Induce Spine Synapse Loss in the Hippocampus of Ovariectomized Mice

    Lepu Zhou;Lars Fester;Breda von Blittersdorff;Basel Hassu

  • Direct and indirect effects of estrogen on rat hippocampus.

    J. Prange-Kiel;G.M. Rune

  • Steroidogenic factor-1 expression in marmoset and rat hippocampus: co-localization with StAR and aromatase.

    U. Wehrenberg;Janine Prange-Kiel;G. M. Rune

  • Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

    Janine Prange-Kiel;Hubertus Jarry;Michael Schoen;Patrick Kohlmann

  • Neurosteroid synthesis in the hippocampus: Role in synaptic plasticity

    Unknown

  • Estrogen up-regulates estrogen receptor α and synaptophysin in slice cultures of rat hippocampus

    G. M. Rune;U. Wehrenberg;Janine Prange-Kiel;L. Zhou

  • Cholesterol‐promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus

    Lars Fester;Lepu Zhou;Andrea Bütow;Cornelia Huber

  • NKCC1-Dependent GABAergic Excitation Drives Synaptic Network Maturation during Early Hippocampal Development

    Carsten K. Pfeffer;Valentin Stein;Damien J. Keating;Hannes Maier

  • Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons

    Janine Prange-Kiel;Lars Fester;Lepu Zhou;Heidrun Lauke

  • Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis

    L. Fester;V. Ribeiro-Gouveia;J. Prange-Kiel;C. Von Schassen

  • Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits

    Ger J A Ramakers;Ger J A Ramakers;David Wolfer;David Wolfer;Georg Rosenberger;Kerstin Kuchenbecker

  • Estrogen-regulated synaptogenesis in the hippocampus: Sexual dimorphism in vivo but not in vitro

    Lars Fester;Janine Prange-Kiel;Lepu Zhou;Breda v. Blittersdorf

Frequent Co-Authors

Roland A. Bender
Roland A. Bender Universität Hamburg
Michael Frotscher
Michael Frotscher Universität Hamburg
Christian Alzheimer
Christian Alzheimer University of Erlangen-Nuremberg
Eva-Maria Mandelkow
Eva-Maria Mandelkow German Center for Neurodegenerative Diseases
Rudi D'Hooge
Rudi D'Hooge KU Leuven
Tobias Sommer
Tobias Sommer Universität Hamburg
Eva Maria Mandelkow
Eva Maria Mandelkow Center of Advanced European Studies and Research
Cordian Beyer
Cordian Beyer RWTH Aachen University
Ken-ichirou Morohashi
Ken-ichirou Morohashi Kyushu University

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