Jacek Biernat

Jacek Biernat publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jacek Biernat sits on this spectrum.

Jacek Biernat D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jacek Biernat sits on this spectrum.

Overview

Best Publications

• Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure.

  M. von Bergen;P. Friedhoff;J. Biernat;J. Heberle

  1231
  Citations

• Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease A PROPERTY COMMON TO MOST CYCLIN-DEPENDENT KINASE INHIBITORS?

  Sophie Leclerc;Matthieu Garnier;Ralph Hoessel;Doris Marko

  1102
  Citations

• Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

  J Biernat;N Gustke;G Drewes;E M Mandelkow

  989
  Citations

• Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau

  Susmitha Ambadipudi;Jacek Biernat;Dietmar Riedel;Eckhard Mandelkow

  783
  Citations

• Domains of tau protein and interactions with microtubules.

  N. Gustke;B. Trinczek;J. Biernat;E.-M. Mandelkow

  772
  Citations

• Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

  G Drewes;B Lichtenberg-Kraag;F Döring;E M Mandelkow

  766
  Citations

• Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

  Marco D Mukrasch;Stefan Bibow;Jegannath Korukottu;Sadasivam Jeganathan

  725
  Citations

• Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau

  E.-M. Mandelkow;G. Drewes;J. Biernat;N. Gustke

  713
  Citations

• RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments

  T. Kampers;P. Friedhoff;J. Biernat;E.-M. Mandelkow

  682
  Citations

• Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

  K. Baumann;E. M. Mandelkow;J. Biernat;Helen Piwnica-Worms

  654
  Citations

• Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure.

  Martin von Bergen;Stefan Barghorn;Li Li;Alexander Marx

  645
  Citations

• Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments.

  A Schneider;J Biernat;M von Bergen;E Mandelkow

  642
  Citations

• The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

  J. Biernat;E.M. Mandelkow;C. Schröter;B. Lichtenberg-Kraag

  606
  Citations

• Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent

  L. Meijer;A. M W H Thunnissen;A. W. White;M. Garnier

  597
  Citations

• Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.

  H Wille;G Drewes;J Biernat;E M Mandelkow

  595
  Citations

• Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

  Harindranath Kadavath;Romina V. Hofele;Jacek Biernat;Satish Kumar

  588
  Citations

• Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments.

  Olaf Schweers;Eva-Maria Mandelkow;Jacek Biernat;Eckhard Mandelkow

  506
  Citations

• Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25

  Maryse Leost;Christiane Schultz;Andreas Link;Yong Zhong Wu

  497
  Citations

• Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.

  Qingyi Zheng-Fischhöfer;Jacek Biernat;Eva-Maria Mandelkow;Susanne Illenberger

  456
  Citations

• Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy AGGREGATION IS TOXIC TO CELLS BUT CAN BE REVERSED BY INHIBITOR DRUGS

  Inna Khlistunova;Jacek Biernat;Yipeng Wang;Marcus Pickhardt

  435
  Citations