World's Best Scientists 2026 revealed!
Edward J. J. Grabowski

Edward J. J. Grabowski

D-Index & Metrics

Chemistry

D-Index
55
Citations
10645
World Ranking
12151
National Ranking
3253

Overview

Edward J. J. Grabowski is affiliated with MSD in the United States. Their research primarily focuses on the field of Chemistry with specific work in Organic Chemistry and Inorganic Chemistry.

The scientist's main research topics include:

  • Asymmetric Hydrogenation and Catalysis
  • Asymmetric Synthesis and Catalysis
  • Cyclopropane Reaction Mechanisms

Edward J. J. Grabowski has published works in the Journal of the American Chemical Society. The documented recent paper is:

  • Correction to "Highly Efficient Asymmetric Synthesis of Sitagliptin", 2020, Journal of the American Chemical Society

Frequent co-authors who have collaborated with Grabowski include:

  • Karl B. Hansen
  • Yi Hsiao
  • Feng Xu
  • Nelo R. Rivera
  • Andrew M. Clausen

Best Publications

  • Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via chiral phase-transfer catalysis

    Ulf H. Dolling;Paul Davis;Edward J. J. Grabowski

  • Oxidation of Primary Alcohols to Carboxylic Acids with Sodium Chlorite Catalyzed by TEMPO and Bleach

    Mangzhu Zhao;Jing Li;Eiichi Mano;Zhiguo Song

  • Direct conversion of activated alcohols to azides using diphenyl phosphorazidate. A practical alternative to mitsunobu conditions

    Andrew S. Thompson;Guy R. Humphrey;Anthony M. DeMarco;David J. Mathre

  • A new general method for preparation of N-methoxy-N-methylamides. Application in direct conversion of an ester to a ketone

    J.Michael Williams;Ronald B. Jobson;Nobuyoshi Yasuda;George Marchesini

  • Highly Efficient Asymmetric Synthesis of Sitagliptin

    Karl B. Hansen;Yi Hsiao;Feng Xu;Nelo Rivera

  • Lithium Alkoxides of Cinchona Alkaloids as Chiral Controllers for Enantioselective Acetylide Addition to Cyclic N-Acyl Ketimines

    Mark A. Huffman;Nobuyoshi Yasuda;Ann E. DeCamp;Edward J. J. Grabowski

  • A practical enantioselective synthesis of .alpha.,.alpha.-diaryl-2-pyrrolidinemethanol. Preparation and chemistry of the corresponding oxazaborolidines

    David J. Mathre;Todd K. Jones;Lyndon C. Xavier;Thomas J. Blacklock

  • A practical process for the preparation of tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole-borane. A highly enantioselective stoichiometric and catalytic reducing agent

    David J. Mathre;Andrew S. Thompson;Alan W. Douglas;Karst Hoogsteen

  • Highly Efficient Synthesis of β-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines

    Yi Hsiao;Nelo R. Rivera;Thorsten Rosner;Shane W. Krska

  • A mechanistic study of the Mitsunobu esterification reaction

    D. L. Hughes;R. A. Reamer;J. J. Bergan;E. J. J. Grabowski

  • A novel chromium trioxide catalyzed oxidation of primary alcohols to the carboxylic acids

    Mangzhu Zhao;Jing Li;Zhiguo Song;Richard Desmond

  • Practical asymmetric synthesis of Efavirenz (DMP 266), an HIV-1 reverse transcriptase inhibitor

    Michael E. Pierce;Rodney L. Parsons;Lilian A. Radesca;Young S. Lo

  • Efficient catalytic asymmetric alkylations. 3. A kinetic and mechanistic study of the enantioselective phase-transfer methylation of 6,7-dichloro-5-methoxy-2-phenyl-1-indanone

    D. L. Hughes;U. H. Dolling;K. M. Ryan;E. F. Schoenewaldt

  • Synthesis of alpha-amido ketones via organic catalysis: thiazolium-catalyzed cross-coupling of aldehydes with acylimines.

    Jerry A. Murry;Doug E. Frantz;Arash Soheili;Richard Tillyer

  • A Novel, Highly Enantioselective Ketone Alkynylation Reaction Mediated by Chiral Zinc Aminoalkoxides

    Lushi Tan;Cheng Yi Chen;Richard D. Tillyer;Edward J.J. Grabowski

  • First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

    Karl B. Hansen;Jaume Balsells;Spencer Dreher;Yi Hsiao

  • Synthesis of substituted imidazoles via organocatalysis.

    Doug E. Frantz;Louis Morency;Arash Soheili;Jerry A. Murry

  • Lithium Ephedrate-Mediated Addition of a Lithium Acetylide to a Ketone: Solution Structures and Relative Reactivities of Mixed Aggregates Underlying the High Enantioselectivities

    Andrew Thompson;Edward G. Corley;Martha F. Huntington;Edward J. J. Grabowski

  • An asymmetric synthesis of MK-0417. Observations on oxazaborolidine-catalyzed reductions

    Todd K. Jones;Julie J. Mohan;Lyndon C. Xavier;Thomas J. Blacklock

  • Use of an ephedrine alkoxide to mediate enantioselective addition of an acetylide to a prochiral ketone: asymmetric synthesis of the reverse transcriptase inhibitor L-743,726

    Andrew S. Thompson;Edward G. Corley;Martha F. Huntington;E.J.J. Grabowski

Frequent Co-Authors

Paul J. Reider
Paul J. Reider Princeton University
Robert A. Reamer
Robert A. Reamer MSD (United States)
Shane W. Krska
Shane W. Krska MSD (United States)
David L. Hughes
David L. Hughes University of East Anglia
Michael H. Fisher
Michael H. Fisher MSD (United States)
Ralph P. Volante
Ralph P. Volante MSD (United States)
Arthur A. Patchett
Arthur A. Patchett MSD (United States)
David B. Collum
David B. Collum Cornell University
John C. Huffman
John C. Huffman Indiana University
Ian W. Davies
Ian W. Davies Princeton University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to diverse career options beyond traditional lab roles. For those interested in the business side of science, pursuing a role as a pharmaceutical sales representative can be lucrative. To learn more about the financial and professional aspects, explore the pharmaceutical sales rep salary and career paths available.

If you prefer a healthcare focus, becoming a pharmacist is a respected and rewarding option. It requires thorough education and licensing, but the path is well-documented. Discover comprehensive steps on how to become a pharmacist to achieve this goal.

For those fascinated by forensic applications of chemistry, roles like autopsy technician can be a unique choice. Specialized training is needed, which you can research further by checking out the educational requirements of autopsy technician school.

Additionally, combining online learning with forensic science offers flexibility and affordability. Several programs provide quality education in this field, which can be explored through the list of online forensic science courses.

Best Scientists Citing Edward J. J. Grabowski

Trending Scientists

Recently Published Articles