D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 48 Citations 8,420 195 World Ranking 11427 National Ranking 3164

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Biochemistry

The scientist’s investigation covers issues in Stereochemistry, Organic chemistry, Chemical synthesis, Biochemistry and Enzyme inhibitor. Michael H. Fisher specializes in Stereochemistry, namely Bicyclic molecule. In the subject of general Organic chemistry, his work in Acylation, Degree of unsaturation and Fermentation broth is often linked to Antiparasitic and Parasite infestation, thereby combining diverse domains of study.

His Chemical synthesis research is multidisciplinary, incorporating elements of Agonist and Trifluoromethyl. His work on Antiprotozoal and Antiprotozoal Agent as part of general Biochemistry research is frequently linked to Histone acetyltransferase, Histone deacetylase and Apicidin, bridging the gap between disciplines. The various areas that Michael H. Fisher examines in his Enzyme inhibitor study include In vivo and Dipeptidyl peptidase.

His most cited work include:

  • (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes (741 citations)
  • Peptidomimetic regulation of growth hormone secretion. (513 citations)
  • Structure and activity of avermectins and milbemycins in animal health (325 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Stereochemistry, Organic chemistry, Chemical synthesis, Pharmacology and Endocrinology. His work on Pharmacophore and Bicyclic molecule is typically connected to Antiparasitic as part of general Stereochemistry study, connecting several disciplines of science. Michael H. Fisher combines subjects such as Active ingredient and Anthelmintic with his study of Organic chemistry.

His Chemical synthesis research is multidisciplinary, incorporating perspectives in Agonist, Selectivity and Carboxamide. His work in the fields of Pharmacology, such as Oral administration, overlaps with other areas such as Sodium channel blocker. His work on Diabetes mellitus, Growth hormone secretagogue and Growth hormone as part of general Endocrinology study is frequently linked to Lipolysis, bridging the gap between disciplines.

He most often published in these fields:

  • Stereochemistry (37.40%)
  • Organic chemistry (19.29%)
  • Chemical synthesis (12.60%)

What were the highlights of his more recent work (between 2000-2010)?

  • Stereochemistry (37.40%)
  • Chemical synthesis (12.60%)
  • Pharmacology (11.02%)

In recent papers he was focusing on the following fields of study:

Michael H. Fisher mainly focuses on Stereochemistry, Chemical synthesis, Pharmacology, Sodium channel blocker and In vivo. His work on Carboxamide as part of general Stereochemistry research is frequently linked to Antiparasitic, thereby connecting diverse disciplines of science. His Chemical synthesis study combines topics in areas such as Bicyclic molecule, Antagonist and Alkyl.

His study in In vivo is interdisciplinary in nature, drawing from both Biochemistry, Enzyme inhibitor, Enzyme, Potency and Tertiary amine. Michael H. Fisher interconnects Biological activity and Substituent in the investigation of issues within Amine gas treating. His Anthelmintic study combines topics from a wide range of disciplines, such as Diethylaminosulfur trifluoride, Organic chemistry and Haemonchus contortus.

Between 2000 and 2010, his most popular works were:

  • (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes (741 citations)
  • Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain (62 citations)
  • Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents (60 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Biochemistry

Stereochemistry, Enzyme inhibitor, Chemical synthesis, Biochemistry and In vivo are his primary areas of study. In his study, Michael H. Fisher carries out multidisciplinary Stereochemistry and Sodium channel blocker research. His biological study deals with issues like Dipeptidyl peptidase, which deal with fields such as IC50.

His research on Chemical synthesis also deals with topics like

  • Amine gas treating which is related to area like Bicyclic molecule, Trifluoromethyl, Carboxamide and Substituent,
  • GnRH Receptor Antagonists and related Affinities. His work in the fields of Biochemistry, such as Antiprotozoal and Protein kinase A, intersects with other areas such as cGMP-dependent protein kinase. His In vivo research is multidisciplinary, relying on both Biological activity, In vitro and Enzyme.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

(2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Dooseop Kim;Liping Wang;Maria Beconi;George J. Eiermann.
Journal of Medicinal Chemistry (2005)

1233 Citations

Peptidomimetic regulation of growth hormone secretion.

Roy G. Smith;Lex H. T. Van der Ploeg;Andrew D. Howard;Scott D. Feighner.
Endocrine Reviews (1997)

800 Citations

Structure and activity of avermectins and milbemycins in animal health

Wesley L. Shoop;Helmut Mrozik;Michael H. Fisher.
Veterinary Parasitology (1995)

549 Citations

Selective hydrogenation products of C-076 compounds and derivatives thereof

John C. Chabala;Michael H. Fisher.
(1978)

331 Citations

Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

Linda L Brockunier;Emma R Parmee;Hyun O Ok;Mari R Candelore.
Bioorganic & Medicinal Chemistry Letters (2000)

269 Citations

Imidazo(1,2-a)pyridine anthelmintic and antifungal agents.

Michael H. Fisher;Aino Lusi.
Journal of Medicinal Chemistry (1972)

241 Citations

Substituted sulfonamides as selective .beta.3 agonists for the treatment of diabetes and obesity

Michael H. Fisher;Elizabeth M. Naylor;Dong Ok;Ann E. Weber.
(1995)

189 Citations

Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

Smith Rg;Pong Ss;Hickey G;Jacks T.
Recent Progress in Hormone Research (1996)

176 Citations

A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429).

William R. Schoen;Judith M. Pisano;Kristine Prendergast;Matthew J. Wyvratt.
Journal of Medicinal Chemistry (1994)

144 Citations

The chemistry and pharmacology of avermectins.

Michael H. Fisher;Helmut Mrozik.
Annual Review of Pharmacology and Toxicology (1992)

138 Citations

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