World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
55
Citations
10753
World Ranking
12136
National Ranking
222

Overview

Matthew J. Wyvratt is affiliated with Medicines for Malaria Venture in Switzerland, contributing research primarily in the domains of materials science and biotechnology. Their work intersects with materials chemistry, applying advanced techniques to study crystallization and solubility as well as microbial metabolism and its applications.

The scientist has authored publications predominantly in the Journal of Medicinal Chemistry and The Cambridge Structural Database. Their recent papers include the following:

  • Arthur A. Patchett Memorial Issue, 2023, Journal of Medicinal Chemistry
  • Annotated Bibliography of Dr. Arthur A. Patchett, 2023, Journal of Medicinal Chemistry
  • CCDC 2358644: Experimental Crystal Structure Determination, 2024, The Cambridge Structural Database

Wyvratt's research encompasses key topics such as crystallization and solubility studies, X-ray diffraction in crystallography, and microbial metabolism and applications. These areas reflect a multidisciplinary approach integrating chemical and biological methods for the advancement of materials science and medicinal chemistry.

Their frequent coauthors reflect collaborations across a range of expertise and include:

  • William J. Greenlee
  • Shuwen He
  • Zhixiong Ye
  • P.H. Dobbelaar
  • I. K. Sebhat

By engaging with established publication venues and coauthoring with multiple researchers, Wyvratt's work contributes to ongoing scientific dialogues in medicinal chemistry and structural databases. Their experience aligns with contemporary research trends focused on crystalline materials and microbial biochemical pathways.

Best Publications

  • (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

    Dooseop Kim;Liping Wang;Maria Beconi;George J. Eiermann

  • A new class of angiotensin-converting enzyme inhibitors

    Patchett Aa;Harris E;Tristram Ew;Wyvratt Mj

  • Peptidomimetic regulation of growth hormone secretion.

    Roy G. Smith;Lex H. T. Van der Ploeg;Andrew D. Howard;Scott D. Feighner

  • Aminoacid derivatives as antihypertensives

    Elbert E. Harris;Arthur A. Patchett;Edward W. Tristram;Matthew J. Wyvratt

  • Recent developments in the design of angiotensin-converting enzyme inhibitors.

    Matthew J. Wyvratt;Arthur A. Patchett

  • Human β3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides

    Linda L Brockunier;Emma R Parmee;Hyun O Ok;Mari R Candelore

  • O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives

    Mark Goulet;William H. Parsons;Peter J. Sinclair;Frederick Wong

  • Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them

    Arthur A. Patchett;Elbert E. Harris;Matthew J. Wyvratt;Edward W. Tristram

  • Benzo-fused lactams promote release of growth hormone

    William R. Schoen;Matthew J. Wyvratt

  • Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

    Smith Rg;Pong Ss;Hickey G;Jacks T

  • Pyrazoleamide compounds are potent antimalarials that target Na + homeostasis in intraerythrocytic Plasmodium falciparum

    Akhil B. Vaidya;Joanne M. Morrisey;Zhongsheng Zhang;Sudipta Das

  • A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429).

    William R. Schoen;Judith M. Pisano;Kristine Prendergast;Matthew J. Wyvratt

  • Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents

    Tesfaye Biftu;Dennis Feng;Michael Fisher;Gui-Bai Liang

  • Benzo-fused lactams that promote the release of growth hormone

    Michael H. Fisher;Matthew J. Wyvratt;William R. Schoen;Robert J. Devita

  • Stimulation of growth hormone release from rat primary pituitary cells by L-692,429, a novel non-peptidyl GH secretagogue

    Kang Cheng;W. W.-S. Chan;B. Butler;L. Wei

  • Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

    Scott B. Hoyt;Clare London;David Gorin;Matthew J. Wyvratt

  • Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1

    Steven L Colletti;Robert W Myers;Sandra J Darkin-Rattray;Anne M Gurnett

  • β-adrenergic agonists

    Michael H. Fisher;Matthew J. Wyvratt

  • Asymmetric Synthesis of Chiral, Nonracemic Trifluoromethyl-Substituted Piperidines and Decahydroquinolines

    Jinlong Jiang;Robert J. DeVita;George A. Doss;and Mark T. Goulet

  • Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist.

    Robert J. DeVita;Darius D. Hollings;Mark T. Goulet;Matthew J. Wyvratt

Frequent Co-Authors

Michael H. Fisher
Michael H. Fisher MSD (United States)
Arthur A. Patchett
Arthur A. Patchett MSD (United States)
Roy G. Smith
Roy G. Smith Scripps Research Institute
Dennis M. Schmatz
Dennis M. Schmatz MSD (United States)
Ann E. Weber
Ann E. Weber MSD (United States)
Margaret A. Cascieri
Margaret A. Cascieri MSD (United States)
Catherine D. Strader
Catherine D. Strader MSD (United States)
David H. Weinberg
David H. Weinberg The Ohio State University
William J. Martin
William J. Martin National Institutes of Health
Lex H.T. Van der Ploeg
Lex H.T. Van der Ploeg MSD (United States)

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in chemistry, pursuing related fields such as forensic science or forensic psychology can open unique career opportunities. Many universities now offer affordable options to study these disciplines remotely, helping students balance education with other commitments. Exploring a forensic degree online is an excellent way to gain specialized knowledge in chemical analysis applied to criminal investigations.

Those seeking advanced study may consider a masters in forensic psychology online, which merges psychological principles with forensic applications. This path often requires an understanding of chemical evidence and toxicology, linking closely with chemistry fundamentals.

Career prospects in forensic science are promising, with salaries reflecting the expertise needed to analyze complex chemical data in legal contexts. Insight into the forensic scientist salary helps students evaluate the potential return on investment from their education.

However, budget considerations are important. Understanding the cost of criminal justice degree programs provides useful context for selecting affordable and reputable online options that complement a chemistry background while preparing for careers in criminal justice and forensic disciplines.

Best Scientists Citing Matthew J. Wyvratt

Recently Published Articles