World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
98
Citations
32240
World Ranking
8975
National Ranking
4619

Overview

John A. Wagner is affiliated with Cygnal Therapeutics in the United States. Their research spans multiple fields within medicine, with a focus on immunology and statistical methods in clinical trials. Contributions to the management of technology and innovation, physiology, and psychiatry and mental health are also evident in their work.

The research topics that John A. Wagner has addressed include:

  • Biosimilars and Bioanalytical Methods
  • Statistical Methods in Clinical Trials
  • Intellectual Property and Patents
  • Biomedical Ethics and Regulation
  • Migraine and Headache Studies
  • Pharmacological Effects and Toxicity Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema

John A. Wagner has published in several journals, with a concentration in:

  • Clinical and Translational Science
  • npj Parkinsonʼs Disease
  • Digital Biomarkers
  • Nature Reviews Drug Discovery
  • The Journal of Immunology

Some of the recent papers associated with their research include:

  • Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males, 2020, Clinical and Translational Science
  • The failure to fail smartly, 2020, Nature Reviews Drug Discovery
  • Accelerating Parkinson's Disease drug development with federated learning approaches, 2024, npj Parkinsonʼs Disease
  • Remote Cardiac Safety Monitoring through the Lens of the FDA Biomarker Qualification Evidentiary Criteria Framework: A Case Study Analysis, 2021, Digital Biomarkers
  • Issue Information, 2023, Clinical and Translational Science

The scientist frequently collaborates with several coauthors, including:

  • Elena S. Izmailova
  • Michael Pacanowski
  • Anuradha Ramamoorthy
  • Yow-Ming Wang
  • Sook Wah Yee

Best Publications

  • Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

    Marc R. Montminy;Kevin A. Sevarino;John A. Wagner;Gail Mandel

  • Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity

    Utpal B. Pajvani;Meredith Hawkins;Terry P. Combs;Michael W. Rajala

  • Induction of Adipocyte Complement-Related Protein of 30 Kilodaltons by PPARγ Agonists: A Potential Mechanism of Insulin Sensitization

    Terry P. Combs;John A. Wagner;Joel Berger;Tom Doebber

  • Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses

    Gary A. Herman;Cathy Stevens;Kristien Van Dyck;Arthur Bergman

  • Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes

    Gary A. Herman;Arthur Bergman;Catherine Stevens;Paul Kotey

  • RETINOIDS REGULATE STEM CELL DIFFERENTIATION

    Lorraine J. Gudas;John A. Wagner

  • Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia.

    Mitsutoshi Endoh;Kenneth Maiese;John Wagner

  • Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop

    Abhijit Guha;Kathleen Dashner;Peter L. Mc Black;John A. Wagner

  • Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies

    Rajesh Krishna;Matt S Anderson;Arthur J Bergman;Bo Jin

  • Brain voltage-sensitive calcium channel subtypes differentiated by ω-conotoxin fraction GVIA

    Ian J. Reynolds;John A. Wagner;Solomon H. Snyder;Stanley A. Thayer

  • Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme.

    Kelem Kassahun;Ian McIntosh;Donghui Cui;David Hreniuk

  • Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers.

    Arthur J. Bergman;Catherine Stevens;YanYan Zhou;Bingming Yi

  • [18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

    H. Donald Burns;Koen Van Laere;Sandra Sanabria-Bohórquez;Terence G. Hamill

  • Biochemistry of Neurotransmitter Release

    Regis B. Kelly;James W. Deutsch;Steven S. Carlson;John A. Wagner

  • A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.

    John A. Wagner;Ilynn B. Nepomuceno;Anna H. Messner;Mary Lynn Moran

  • The mangled extremity syndrome (M.E.S.): a severity grading system for multisystem injury of the extremity.

    Roger Gregory;Randolph Gould;Marie Peclet;John Wagner

  • Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.

    A.C. Chao;F.J. de Sauvage;Y.J. Dong;J.A. Wagner

  • Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension.

    Goutam C. Mistry;Andrea L. Maes;Kenneth C. Lasseter;Michael J. Davies

  • Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus

    John A Wagner;Thomas Reynolds;Mary Lynn Moran;Richard B Moss

  • Activation of chloride channels in normal and cystic fibrosis airway epithelial cells by multifunctional calcium/calmodulin-dependent protein kinase.

    John A. Wagner;Alison L. Cozens;Howard Schulman;Dieter C. Gruenert

Frequent Co-Authors

Richard D. Granstein
Richard D. Granstein Cornell University
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Patricia A. D'Amore
Patricia A. D'Amore Massachusetts Eye and Ear Infirmary
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Michael J. Davies
Michael J. Davies University of Copenhagen
Richard B. Moss
Richard B. Moss Stanford University
Regis B. Kelly
Regis B. Kelly University of California, San Francisco
Jeffrey J. Wine
Jeffrey J. Wine Stanford University
Richard Hargreaves
Richard Hargreaves Harvard Medical School
Henry N. Ginsberg
Henry N. Ginsberg Columbia University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The healthcare field offers a variety of accessible education and career options beyond traditional medical degrees. For those with an RN qualification, pursuing an rn to bsn online can be an affordable and convenient way to advance your career and boost your earning potential.

If you hold a non-nursing bachelor’s degree, you might consider direct entry msn programs for non-nursing majors. These bridge programs provide a pathway to advanced practice roles in nursing, even for those without a previous nursing background.

Entry into nursing can also be made easier with programs highlighted among whats the easiest nursing program to get into?, helping students start their careers more quickly and efficiently.

Not all healthcare careers require a clinical component. Medical billing and coding is a high-demand field that can often be studied fully online. Learn more about whether can you get financial aid for medical billing and coding as you plan your educational journey.

Best Scientists Citing John A. Wagner

Trending Scientists

Recently Published Articles