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Biology and Biochemistry

D-Index
78
Citations
20031
World Ranking
4589
National Ranking
2232

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Richard R. Neubig is affiliated with Michigan State University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, pulmonary and respiratory medicine, genetics, oncology, and cell biology as key subfields.

The scientist has contributed significantly to research on topics including melanoma and MAPK pathways, receptor mechanisms and signaling, interstitial lung diseases and idiopathic pulmonary fibrosis, genetics and neurodevelopmental disorders, Hippo pathway signaling and YAP/TAZ, cellular transport and secretion, and cancer mechanisms and therapy.

Several recent papers illustrate the diversity of Neubig's work. These include:

  • COVID-19-A Theory of Autoimmunity Against ACE-2 Explained (2021), published in Frontiers in Immunology
  • Mice with GNAO1 R209H Movement Disorder Variant Display Hyperlocomotion Alleviated by Risperidone (2020), published in the Journal of Pharmacology and Experimental Therapeutics
  • Prevention of bleomycin-induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway (2022), published in Pharmacology Research & Perspectives
  • Convergent olfactory trace amine-associated receptors detect biogenic polyamines with distinct motifs via a conserved binding site (2021), published in Journal of Biological Chemistry
  • Ibrutinib Blocks YAP1 Activation and Reverses BRAF Inhibitor Resistance in Melanoma Cells (2021), published in Molecular Pharmacology

Neubig frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), IUPHAR/BPS Guide to Pharmacology CITE, Journal of Pharmacology and Experimental Therapeutics, Molecular Pharmacology, and Spartan Medical Research Journal.

Frequent collaborators of Neubig include Erika M. Lisabeth, S P H Alexander, Jim Battey, Helen E. Benson, and Richard V. Benya.

They were awarded the Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • International Union of Pharmacology. XLVI. G Protein-Coupled Receptor List

    Steven M. Foord;Tom I. Bonner;Richard R. Neubig;Edward M. Rosser

  • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology

    Richard R. Neubig;Michael Spedding;Terry Kenakin;Arthur Christopoulos

  • Phagocyte-derived catecholamines enhance acute inflammatory injury

    Michael A. Flierl;Daniel Rittirsch;Brian A. Nadeau;Anthony J. Chen

  • The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State

    G. Enrico Rovati;Valérie Capra;Richard R. Neubig

  • Regulators of G-protein Signalling as New Central Nervous System Drug Targets

    Richard R. Neubig;David P. Siderovski

  • Membrane organization in G-protein mechanisms.

    Richard R. Neubig

  • Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.

    Richard R. Neubig;Elizabeth K. Krodel;Norman D. Boyd;Jonathan B. Cohen

  • International Union of Basic and Clinical Pharmacology. LXXXVIII. G Protein-Coupled Receptor List: Recommendations for New Pairings with Cognate Ligands

    Anthony P. Davenport;Stephen P. H. Alexander;Joanna L. Sharman;Adam J. Pawson

  • International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers

    Jean Philippe Pin;Richard Neubig;Michel Bouvier;Lakshmi Devi

  • Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by Torpedo postsynaptic membranes: stoichiometry and ligand interactions.

    Richard R. Neubig;Jonathan B. Cohen

  • International Union of Pharmacology. LVI. Ghrelin Receptor Nomenclature, Distribution, and Function

    Anthony P. Davenport;Tom I. Bonner;Steven M. Foord;Anthony J. Harmar

  • IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels

    Anthony J. Harmar;Rebecca A. Hills;Edward M. Rosser;Martin Jones

  • Structure of Gαq-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs

    Susanne Lutz;Aruna Shankaranarayanan;Aruna Shankaranarayanan;Cassandra Coco;Marc Ridilla;Marc Ridilla

  • Regulator of G protein signaling proteins: novel multifunctional drug targets.

    Huailing Zhong;Richard R. Neubig

  • M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

    Weixing Shen;Joshua L. Plotkin;Veronica Francardo;Wai Kin D. Ko;Wai Kin D. Ko

  • CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling

    Chris R. Evelyn;Susan M. Wade;Qin Wang;Mei Wu

  • International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands

    Arthur Christopoulos;Jean Pierre Changeux;William A. Catterall;Doriano Fabbro

  • Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles.

    Levi L Blazer;Richard R Neubig

  • Permeability control by cholinergic receptors in Torpedo postsynaptic membranes: agonist dose-response relations measured at second and millisecond times.

    Richard R. Neubig;Jonathan B. Cohen

  • A point mutation in Gα(o) and Gα(i1) blocks interaction with regulator of G protein signaling proteins

    Keng Li Lan;Noune A. Sarvazyan;Ronald Taussig;Robert G. Mackenzie

Frequent Co-Authors

Scott D. Larsen
Scott D. Larsen University of Michigan–Ann Arbor
Michael Spedding
Michael Spedding DuPont (United States)
Henry I. Mosberg
Henry I. Mosberg University of Michigan–Ann Arbor
Roger K. Sunahara
Roger K. Sunahara University of California, San Diego
Jean-Philippe Pin
Jean-Philippe Pin University of Montpellier
Anthony P. Davenport
Anthony P. Davenport University of Cambridge
Jennifer J. Linderman
Jennifer J. Linderman University of Michigan–Ann Arbor
Anthony J. Harmar
Anthony J. Harmar University of Edinburgh
Tom I. Bonner
Tom I. Bonner National Institutes of Health
Shuichi Takayama
Shuichi Takayama Georgia Institute of Technology

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