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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
27471
World Ranking
5225
National Ranking
2483

Overview

David P. Siderovski is affiliated with West Virginia University in the United States. Their research work primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Within these broad disciplines, their publications focus on specific subfields such as Molecular Biology, Surgery, Physiology, Oncology, and Infectious Diseases.

The scientist's main research topics include:

  • Protein Kinase Regulation and GTPase Signaling
  • Amoebic Infections and Treatments
  • Pancreatitis Pathology and Treatment
  • Glycosylation and Glycoproteins Research
  • Biochemical and Molecular Research
  • Peptidase Inhibition and Analysis
  • Receptor Mechanisms and Signaling

David P. Siderovski has published extensively, with a notable concentration in the venue UNC Libraries, where 63 of their works appear. Other venues with multiple publications include OPAL (Open@LaTrobe) at La Trobe University, the Journal of Biological Chemistry, The FASEB Journal, and the International Journal of Molecular Sciences.

Among recent papers associated with this researcher are:

  • Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice, 2020, UNC Libraries
  • Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review, 2020, Anesthesia & Analgesia
  • G-protein signaling: back to the future, 2020, UNC Libraries
  • Regulation of T cell activation, anxiety, and male aggression by RGS2, 2020, UNC Libraries
  • Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells, 2021, UNC Libraries

Coauthorship collaborations feature prominently in their research, with frequent collaborators including:

  • Francis S. Willard
  • Dustin E. Bosch
  • Adam J. Kimple
  • Christopher A. Johnston
  • Patrick M. Giguère

Best Publications

  • Molecular characterization of mitochondrial apoptosis-inducing factor

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

    Vuk Stambolic;Vuk Stambolic;Akira Suzuki;Akira Suzuki;José Luis de la Pompa;José Luis de la Pompa

  • 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

    Susan McCracken;Nova Fong;Emanuel Rosonina;Krassimir Yankulov

  • G-protein signaling: back to the future

    C. R. McCudden;M. D. Hains;R. J. Kimple;D. P. Siderovski

  • The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

    David P. Siderovski;Francis S. Willard

  • Regulators of G-protein Signalling as New Central Nervous System Drug Targets

    Richard R. Neubig;David P. Siderovski

  • Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

    K Mary Tang;Guang-rong Wang;Ping Lu;Richard H Karas

  • Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

    John M. Lambert;Que T. Lambert;Gary W. Reuther;Angeliki Malliri

  • A Seven-Transmembrane RGS Protein That Modulates Plant Cell Proliferation

    Jin Gui Chen;Francis S. Willard;Jirong Huang;Jiansheng Liang

  • A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits

    Bryan E. Snow;Andrejs M. Krumins;Sheu Fen Lee

  • Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

    Tatsuya Ingi;Andrejs M. Krumins;Peter Chidiac

  • Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos.

    Kelly Colombo;Stephan W. Grill;Randall J. Kimple;Francis S. Willard

  • The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

    Yu Lei;Haitao Wen;Yanbao Yu;Debra J. Taxman

  • Regulation of T cell activation, anxiety, and male aggression by RGS2.

    Antonio J. Oliveira-dos-Santos;Goichi Matsumoto;Bryan E. Snow;Donglin Bai

  • Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

    Mark T. Uhlik;Brenda Temple;Sompop Bencharit;Adam J. Kimple

  • The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo

    Y Liu;B.E Snow;M.P Hande;D Yeung;D Yeung

  • A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

    Kent L. Rossman;David K. Worthylake;Jason T. Snyder;David P. Siderovski

  • Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

    Randall J. Kimple;Michelle E. Kimple;Laurie Betts;John E Sondek

  • Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets

    Adam J. Kimple;Dustin E. Bosch;Patrick M. Giguère;David P. Siderovski

  • A new family of regulators of G-protein-coupled receptors?

    David P. Siderovski;Andrew Hessel;Stephen Chung;Tak W. Mak

Frequent Co-Authors

Francis S. Willard
Francis S. Willard Eli Lilly (United States)
John Sondek
John Sondek University of North Carolina at Chapel Hill
T. Kendall Harden
T. Kendall Harden University of North Carolina at Chapel Hill
Josef M. Penninger
Josef M. Penninger University of British Columbia
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre
Mischa Machius
Mischa Machius The University of Texas Southwestern Medical Center
Mark A. Giembycz
Mark A. Giembycz University of Calgary

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