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Biology and Biochemistry

D-Index
50
Citations
7998
World Ranking
17726
National Ranking
1281

Overview

Eishi Ashihara is affiliated with Kyoto Pharmaceutical University in Japan. Their academic output primarily spans the fields of Biochemistry, Genetics and Molecular Biology with 32 publications, and Medicine with 20 publications. Within these broad areas, Ashihara's subfields of study include Molecular Biology, Immunology, Oncology, Hematology, and Cancer Research.

The scientist's research topics include:

  • Ubiquitin and proteasome pathways
  • Protein degradation and inhibitors
  • Multiple myeloma research and treatments
  • Immune cell function and interaction
  • T-cell and B-cell immunology
  • Extracellular vesicles in disease
  • RNA interference and gene delivery

Ashihara has several recent papers illustrating their research interests. These include:

  • "Plasma membrane anchored nanosensor for quantifying endogenous production of H2O2 in living cells" (2021), published in Biosensors and Bioelectronics
  • "Cytotoxic activities of sesquiterpenoids from the aerial parts of Petasites japonicus against cancer stem cells" (2020), published in Journal of Natural Medicines
  • "Human Vγ9Vδ2 T cells exert anti-tumor activity independently of PD-L1 expression in tumor cells" (2021), published in Biochemical and Biophysical Research Communications
  • "Strategies to Improve the Antitumor Effect of γδ T Cell Immunotherapy for Clinical Application" (2021), published in International Journal of Molecular Sciences
  • "Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ" (2020), published in Neuroscience

Frequent co-authors of Ashihara include:

  • Yuki Toda
  • Shigekuni Hosogi
  • Kazuyuki Takata
  • Mako Tomogane
  • Teruki Shimizu

Among frequent publication venues, Ashihara has contributed notably to:

  • Biochemical and Biophysical Research Communications (6 publications)
  • Journal of Natural Medicines (2 publications)
  • Anticancer Research (2 publications)
  • Biosensors and Bioelectronics (1 publication)
  • International Journal of Molecular Sciences (1 publication)

Best Publications

  • Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

    Kazuyuki Takata;Kazuyuki Takata;Tatsuya Kozaki;Christopher Zhe Wei Lee;Morgane Sonia Thion

  • NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.

    Shinya Kimura;Haruna Naito;Hidekazu Segawa;Junya Kuroda

  • Targeting the Wnt/β-catenin signaling pathway in human cancers.

    Hisayuki Yao;Eishi Ashihara;Eishi Ashihara;Taira Maekawa

  • Myeloid-Derived Suppressor Cells Play Crucial Roles in the Regulation of Mouse Collagen-Induced Arthritis

    Wataru Fujii;Eishi Ashihara;Eishi Ashihara;Hideyo Hirai;Hidetake Nagahara

  • Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration.

    Kento Tateishi;Eishi Ashihara;Naofumi Takehara;Tetsuya Nomura;Tetsuya Nomura

  • INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity

    Asumi Yokota;Shinya Kimura;Satohiro Masuda;Eishi Ashihara

  • Rituximab is effective for steroid-refractory sclerodermatous chronic graft-versus-host disease.

    M Okamoto;A Okano;S Akamatsu;E Ashihara

  • Intracoronary Transplantation of Non-Expanded Peripheral Blood-Derived Mononuclear Cells Promotes Improvement of Cardiac Function in Patients With Acute Myocardial Infarction

    Tetsuya Tatsumi;Eishi Ashihara;Toshihide Yasui;Shinsaku Matsunaga

  • Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways

    T Kobayashi;J Kuroda;E Ashihara;S Oomizu

  • Targeting the canonical Wnt/β-catenin pathway in hematological malignancies.

    Eishi Ashihara;Tetsuya Takada;Taira Maekawa

  • Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia

    Mio Yamamoto-Sugitani;Junya Kuroda;Eishi Ashihara;Hisao Nagoshi

  • Human cardiac stem cells exhibit mesenchymal features and are maintained through Akt/GSK-3β signaling

    Kento Tateishi;Eishi Ashihara;Shoken Honsho;Shoken Honsho;Naofumi Takehara

  • Zoledronic Acid -a Multiplicity of Anti-Cancer Action

    Takeshi Yuasa;Shinya Kimura;Eishi Ashihara;Tomonori Habuchi

  • Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines.

    Yasuyuki Deguchi;Shinya Kimura;Eishi Ashihara;Tomoko Niwa

  • Non–T-cell–depleted HLA haploidentical stem cell transplantation in advanced hematologic malignancies based on the feto-maternal michrochimerism

    Chihiro Shimazaki;Naoya Ochiai;Ryo Uchida;Akira Okano

  • Synergistic Effect of FLT-3 Ligand on the Granulocyte Colony-Stimulating Factor–Induced Mobilization of Hematopoietic Stem Cells and Progenitor Cells Into Blood in Mice

    Yoshikazu Sudo;Chihiro Shimazaki;Eishi Ashihara;Takehisa Kikuta

  • B-cell lymphoma associated with haemophagocytic syndrome: a clinical, immunological and cytogenetic study.

    Chihiro Shimazaki;Tohru Inaba;Kazuho Shimura;Akio Okamoto

  • Significance of C4d staining in ABO-identical/compatible liver transplantation

    Hiromi Sakashita;Hironori Haga;Eishi Ashihara;Mei Chin Wen

  • Future prospect of RNA interference for cancer therapies.

    Eishi Ashihara;Eri Kawata;Taira Maekawa

  • Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia

    J Kuroda;S Kimura;A Strasser;M Andreeff

Frequent Co-Authors

Masafumi Taniwaki
Masafumi Taniwaki Kyoto Prefectural University of Medicine
Jiro Imanishi
Jiro Imanishi Kyoto Prefectural University of Medicine
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Shun Shimohama
Shun Shimohama Sapporo Medical University
Michael Andreeff
Michael Andreeff The University of Texas MD Anderson Cancer Center
Hiroto Egawa
Hiroto Egawa Kyoto University
Masatsugu Horiuchi
Masatsugu Horiuchi Ehime University
Satohiro Masuda
Satohiro Masuda Himeji Dokkyo University
Kazuma Ohyashiki
Kazuma Ohyashiki Tokyo Medical University
Akira Yamauchi
Akira Yamauchi Kawasaki Medical School

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