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Biology and Biochemistry

D-Index
48
Citations
10481
World Ranking
18283
National Ranking
7470

Overview

Krishna Singh is affiliated with East Tennessee State University in the United States. Their research largely focuses on the intersection of biochemistry, genetics, and molecular biology, with significant contributions in medicine. Within these broad fields, they specialize in molecular biology, genetics, cardiology and cardiovascular medicine, immunology, and cellular and molecular neuroscience.

The primary research topics explored by Krishna Singh include:

  • Mitochondrial Function and Pathology
  • Cardiac Fibrosis and Remodeling
  • Genetic Neurodegenerative Diseases
  • Cardiac Ischemia and Reperfusion
  • Genetics and Neurodevelopmental Disorders
  • Ubiquitin and Proteasome Pathways
  • Peptidase Inhibition and Analysis

Krishna Singh has published extensively in a range of scientific journals, with frequent contributions to the following venues:

  • Life Sciences
  • ACS Pharmacology & Translational Science
  • The FASEB Journal
  • Current Opinion in Pharmacology
  • Biology

Recent publications by Krishna Singh include:

  • Heart failure and diabetes: role of ATM (2020), published in Current Opinion in Pharmacology
  • Exogenous ubiquitin attenuates hypoxia/reoxygenation-induced cardiac myocyte apoptosis via the involvement of CXCR4 and modulation of mitochondrial homeostasis (2020), published in Biochemistry and Cell Biology
  • Macrophages in the Inflammatory Phase following Myocardial Infarction: Role of Exogenous Ubiquitin (2023), published in Biology
  • Post-ischemic cardioprotective potential of exogenous ubiquitin in myocardial remodeling late after ischemia/reperfusion injury (2022), published in Life Sciences
  • A DNA aptamer-based assay for the detection of soluble ST2, a prognostic biomarker for monitoring heart failure (2023), published in International Journal of Biological Macromolecules

Frequently collaborating with Krishna Singh are several researchers, including:

  • Suman Dalal
  • Mahipal Singh
  • Paige L. Shook
  • Amit Kumar
  • Mary C. Wingard

Best Publications

  • Norepinephrine Stimulates Apoptosis in Adult Rat Ventricular Myocytes by Activation of the β-Adrenergic Pathway

    Catherine Communal;Krishna Singh;David R. Pimentel;Wilson S. Colucci

  • Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein.

    Catherine Communal;Krishna Singh;Douglas B. Sawyer;Wilson S. Colucci

  • Role of Oxidative Stress in Myocardial Hypertrophy and Failure

    Douglas B. Sawyer;Deborah A. Siwik;Lei Xiao;David R. Pimentel

  • Reactive Oxygen Species Mediate Amplitude-Dependent Hypertrophic and Apoptotic Responses to Mechanical Stretch in Cardiac Myocytes

    David R. Pimentel;Jay K. Amin;Lei Xiao;Thomas Miller

  • Exaggerated Left Ventricular Dilation and Reduced Collagen Deposition After Myocardial Infarction in Mice Lacking Osteopontin

    Nathan A. Trueblood;Zhonglin Xie;Catherine Communal;Flora Sam

  • Myocardial-directed overexpression of the human β1-adrenergic receptor in transgenic mice

    John D Bisognano;Howard D Weinberger;Teresa J Bohlmeyer;Aldo Pende;Aldo Pende

  • β-Adrenergic Receptor–Stimulated Apoptosis in Cardiac Myocytes Is Mediated by Reactive Oxygen Species/c-Jun NH2-Terminal Kinase–Dependent Activation of the Mitochondrial Pathway

    Andrea Remondino;Susan H. Kwon;Catherine Communal;David R. Pimentel

  • Role of reactive oxygen species and NAD(P)H oxidase in α1-adrenoceptor signaling in adult rat cardiac myocytes

    Lei Xiao;David R. Pimentel;Jing Wang;Krishna Singh

  • Inhibition of Copper-Zinc Superoxide Dismutase Induces Cell Growth, Hypertrophic Phenotype, and Apoptosis in Neonatal Rat Cardiac Myocytes In Vitro

    Deborah A. Siwik;John D. Tzortzis;David R. Pimental;Donny L.-F. Chang

  • Adrenergic regulation of cardiac myocyte apoptosis.

    Krishna Singh;Lei Xiao;Lei Xiao;Andrea Remondino;Andrea Remondino;Douglas B. Sawyer;Douglas B. Sawyer

  • Developmental Expression of Osteopontin (OPN) mRNA in Rat Tissues: Evidence for a Role for OPN in Bone Formation and Resorption

    Jinkun Chen;Krishna Singh;Barid B. Mukherjee;Jaro Sodek

  • Reactive Oxygen Species Mediate Alpha-adrenergic Receptor-stimulated Hypertrophy in Adult Rat Ventricular Myocytes

    Jay K Amin;Lei Xiao;Lei Xiao;David R Pimental;David R Pimental;Patrick J Pagano;Patrick J Pagano

  • p38 Mitogen-activated Protein Kinase Pathway Protects Adult Rat Ventricular Myocytes against β-Adrenergic Receptor-stimulated Apoptosis EVIDENCE FOR Gi-DEPENDENT ACTIVATION

    Catherine Communal;Wilson S. Colucci;Krishna Singh

  • Differential Regulation of Matrix Metalloproteinase-2 and -9 Expression and Activity in Adult Rat Cardiac Fibroblasts in Response to Interleukin-1β *

    Zhonglin Xie;Mahipal Singh;Krishna Singh

  • Adrenergic regulation of myocardial apoptosis.

    Krishna Singh;Catherine Communal;Douglas B. Sawyer;Wilson S. Colucci

  • An intrinsic adrenergic system in mammalian heart.

    M H Huang;D S Friend;M E Sunday;K Singh

  • Mice Lacking Inducible Nitric Oxide Synthase Have Improved Left Ventricular Contractile Function and Reduced Apoptotic Cell Death Late After Myocardial Infarction

    Flora Sam;Douglas B. Sawyer;Zhonglin Xie;Donny L.F. Chang

  • MEK1/2–ERK1/2 Mediates α1-Adrenergic Receptor-stimulated Hypertrophy in Adult Rat Ventricular Myocytes ☆

    Lei Xiao;David R Pimental;Jay K Amin;Krishna Singh

  • Myocardial Osteopontin Expression Coincides With the Development of Heart Failure

    Krishna Singh;Geza Sirokman;Catherine Communal;Kathleen G. Robinson

  • Physiological properties and differential glycosylation of phosphorylated and nonphosphorylated forms of osteopontin secreted by normal rat kidney cells.

    Krishna Singh;M. W. Devouge;B. B. Mukherjee

Frequent Co-Authors

Wilson S. Colucci
Wilson S. Colucci Boston University
Douglas B. Sawyer
Douglas B. Sawyer Maine Medical Center
Patrick J. Pagano
Patrick J. Pagano University of Pittsburgh
Anil B. Mukherjee
Anil B. Mukherjee National Institutes of Health
William L. Stanford
William L. Stanford Ottawa Hospital
Michael D. Schneider
Michael D. Schneider Imperial College London
Daniel S. Friend
Daniel S. Friend Brigham and Women's Hospital
Michael R. Bristow
Michael R. Bristow University of Colorado Anschutz Medical Campus
Thomas W. Smith
Thomas W. Smith University of California, Davis
Bhudev C. Das
Bhudev C. Das University of Delhi

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