World's Best Scientists 2026 revealed!

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Medicine

D-Index
119
Citations
50002
World Ranking
3908
National Ranking
2137

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Roger J. Hajjar is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans multiple domains within medicine, with a particular focus on cardiology and cardiovascular medicine, molecular biology, genetics, surgery, and biomedical engineering.

The scientist's primary fields of study include:

  • Medicine (91 publications)
  • Biochemistry, Genetics and Molecular Biology (63 publications)

Their subfields of specialization incorporate:

  • Cardiology and Cardiovascular Medicine (59 publications)
  • Molecular Biology (43 publications)
  • Genetics (17 publications)
  • Surgery (9 publications)
  • Biomedical Engineering (6 publications)

Main research topics covered by their work include:

  • Virus-based gene therapy research (28 publications)
  • Cardiac electrophysiology and arrhythmias (26 publications)
  • Cardiomyopathy and Myosin Studies (24 publications)
  • Viral Infections and Immunology Research (22 publications)
  • CRISPR and Genetic Engineering (18 publications)
  • Cardiac Fibrosis and Remodeling (12 publications)
  • Cardiovascular Effects of Exercise (12 publications)

Frequent publication venues for their work are:

  • Circulation (9 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Circulation Research (4 publications)
  • Molecular Therapy (3 publications)
  • Journal of Molecular and Cellular Cardiology (3 publications)

They have collaborated frequently with several researchers, including:

  • Evangelia G. Kranias (12 joint publications)
  • Elena Chepurko (9 joint publications)
  • Lior Zangi (9 joint publications)
  • Dongtak Jeong (9 joint publications)
  • Anthony S. Fargnoli (8 joint publications)

Selected recent papers illustrate the scope of their research:

  • "Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration," 2020, Circulation
  • "Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response After Myocardial Infarction," 2020, Circulation
  • "Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome," 2021, Cell Host & Microbe
  • "Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL," 2020, Gene Therapy
  • "Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart," 2023, Circulation

Roger J. Hajjar has been recognized as a member of the Association of American Physicians.

Best Publications

  • Apoptosis in Myocytes in End-Stage Heart Failure

    J Narula;N Haider;R Virmani;T G DiSalvo

  • Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID) A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca2+-ATPase in Patients With Advanced Heart Failure

    Mariell Jessup;Barry Greenberg;Donna Mancini;Thomas Cappola

  • Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo

    Takashi Matsui;Jingzang Tao;Federica del Monte;Kyung-Han Lee

  • Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice

    Peter J. Kuhlencordt;Robert Gyurko;Fred Han;Marielle Scherrer-Crosbie

  • Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair

    Bernhard Kühn;Federica del Monte;Roger J Hajjar;Roger J Hajjar;Yuh-Shin Chang

  • Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy

    Ning Sun;Masayuki Yazawa;Jianwei Liu;Leng Han

  • Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

    Michael I. Miyamoto;Federica del Monte;Ulrich Schmidt;Thomas S. DiSalvo

  • Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

    Brian E. Jaski;Mariell L. Jessup;Donna M. Mancini;Thomas P. Cappola

  • Restoration of Contractile Function in Isolated Cardiomyocytes From Failing Human Hearts by Gene Transfer of SERCA2a

    Federica del Monte;Sian E. Harding;Ulrich Schmidt;Takashi Matsui

  • Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

    Evangelia G. Kranias;Roger J. Hajjar

  • Improvement in Survival and Cardiac Metabolism After Gene Transfer of Sarcoplasmic Reticulum Ca2+-ATPase in a Rat Model of Heart Failure

    Federica del Monte;Eric Williams;Djemal Lebeche;Ulrich Schmidt

  • Glycogen Synthase Kinase-3β Is a Negative Regulator of Cardiomyocyte Hypertrophy

    Syed Haq;Gabriel Choukroun;Zhao Bin Kang;Hardeep Ranu

  • Differential Activation of Signal Transduction Pathways in Human Hearts With Hypertrophy Versus Advanced Heart Failure

    Syed Haq;Gabriel Choukroun;Hae Lim;Kevin M. Tymitz

  • Functional Consequences of Caspase Activation in Cardiac Myocytes

    Catherine Communal;Marius Sumandea;Pieter de Tombe;Jagat Narula

  • Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

    Solene M Evrard;Laura Lecce;Katherine C Michelis;Aya Nomura-Kitabayashi

  • Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics.

    Carlos G. Santos-Gallego;Carlos G. Santos-Gallego;Juan Antonio Requena-Ibanez;Rodolfo San Antonio;Kiyotake Ishikawa

  • FTO-Dependent N 6 -Methyladenosine Regulates Cardiac Function During Remodeling and Repair.

    Prabhu Mathiyalagan;Marta Adamiak;Joshua Mayourian;Yassine Sassi

  • Titin Isoform Switch in Ischemic Human Heart Disease

    Ciprian Neagoe;Michael Kulke;Federica del Monte;Judith K. Gwathmey

  • Inhibition of miR-25 improves cardiac contractility in the failing heart

    Christine Wahlquist;Dongtak Jeong;Agustin Rojas-Muñoz;Changwon Kho

  • Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

    Takashi Matsui;Ling Li;Federica del Monte;Yasuhisa Fukui

Frequent Co-Authors

Valentin Fuster
Valentin Fuster Icahn School of Medicine at Mount Sinai
Juan J. Badimon
Juan J. Badimon Icahn School of Medicine at Mount Sinai
Evangelia G. Kranias
Evangelia G. Kranias University of Cincinnati Medical Center
Anthony Rosenzweig
Anthony Rosenzweig Harvard University
Ronald A. Li
Ronald A. Li University of Hong Kong
John V. Frangioni
John V. Frangioni Beth Israel Deaconess Medical Center
Zahi A. Fayad
Zahi A. Fayad Icahn School of Medicine at Mount Sinai
Ronglih Liao
Ronglih Liao Stanford University
Jagat Narula
Jagat Narula Icahn School of Medicine at Mount Sinai

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