World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
13259
World Ranking
11931
National Ranking
5122

Overview

Chuan-Yuan Li is affiliated with Duke University in the United States and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research spans several interconnected subfields including Molecular Biology, Immunology, Oncology, Cancer Research, and Pulmonary and Respiratory Medicine.

The scientist's work focuses on key topics related to cancer biology and immunotherapy. These topics include Cancer Immunotherapy and Biomarkers, Ferroptosis and cancer prognosis, interferon and immune responses, DNA Repair Mechanisms, RNA modifications and cancer, Immune Cell Function and Interaction, and the mechanisms and regulation of Cell death.

Among their recent publications are the following papers:

  • Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer, 2020, Nature
  • ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation, 2020, Journal of Clinical Investigation
  • A Gene Mutation Signature Predicting Immunotherapy Benefits in Patients With NSCLC, 2020, Journal of Thoracic Oncology
  • Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy, 2020, Radiation Research
  • SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy, 2022, Cancer Research

Chuan-Yuan Li frequently collaborates with other researchers. Frequent co-authors in their publications include:

  • Xuhui Bao
  • Mengjie Hu
  • Meng Jiao
  • Xinjian Liu
  • Dong Pan

The scientist publishes regularly in a range of academic journals and venues, with repeated contributions to Cancer Research, Advanced Science, PubMed, Radiation Research, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy

    Qian Huang;Fang-Fang Li;Xinjian Liu;Wenrong Li

  • Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration.

    Fang Li;Qian Huang;Qian Huang;Jiang Chen;Yuanlin Peng

  • Regulation of HIF-1α Stability through S-nitrosylation

    Fang Li;Pierre Sonveaux;Pierre Sonveaux;Zahid N. Rabbani;Shanling Liu;Shanling Liu

  • Initial Stages of Tumor Cell-Induced Angiogenesis: Evaluation Via Skin Window Chambers in Rodent Models

    Chuan Yuan Li;Siqing Shan;Qian Huang;Rod D. Braun

  • Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

    Chuan-Yuan Li;Laurent Suardet;John B. Little

  • Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.

    Xinjian Liu;Xuhui Bao;Mengjie Hu;Hanman Chang

  • Caspase-3 Promotes Genetic Instability and Carcinogenesis

    Xinjian Liu;Yujun He;Fang Li;Qian Huang

  • Caspase-3 regulates the migration, invasion and metastasis of colon cancer cells.

    Min Zhou;Xinjian Liu;Zonghai Li;Qian Huang

  • Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells.

    Xinjian Liu;Xinjian Liu;Fang Li;Elizabeth A. Stubblefield;Barbara Blanchard

  • Heat-induced gene expression as a novel targeted cancer gene therapy strategy.

    Qian Huang;Jim K. Hu;Frank Lohr;Li Zhang

  • Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.

    Bin Yan;Huili Wang;Zahid N. Rabbani;Yulin Zhao

  • GW112, A Novel Antiapoptotic Protein That Promotes Tumor Growth

    Xiuwu Zhang;Qian Huang;Zhonghui Yang;Yongping Li

  • ABSENCE OF RADIATION-INDUCED G1 ARREST IN TWO CLOSELY RELATED HUMAN LYMPHOBLAST CELL LINES THAT DIFFER IN P53 STATUS

    John B. Little;Hatsumi Nagasawa;Peter C. Keng;Yongjia Yu

  • ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage and cGAS/STING activation

    Mengjie Hu;Min Zhou;Xuhui Bao;Dong Pan

  • Effective Tumor Therapy with Plasmid-encoded Cytokines Combined with in Vivo Electroporation

    Frank Lohr;David Y. Lo;David A. Zaharoff;Kang Hu

  • Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α

    Xiuwu Zhang;Takashi Kon;He Wang;Fang Li

  • Apoptotic Caspases Regulate Induction of iPSCs from Human Fibroblasts

    Fang Li;Zhimin He;Zhimin He;Jingping Shen;Qian Huang;Qian Huang

  • Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth

    Yiting Cao;Pierre Sonveaux;Shanling Liu;Yulin Zhao

  • Observation of Incipient Tumor Angiogenesis That Is Independent of Hypoxia and Hypoxia Inducible Factor-1 Activation

    Yiting Cao;Chuan-Yuan Li;Benjamin J. Moeller;Daohai Yu

  • Tumor necrosis factor-α is a potent endogenous mutagen that promotes cellular transformation

    B. Yan;H. Wang;Z. N. Rabbani;M. W. Dewhirst

Frequent Co-Authors

Mark W. Dewhirst
Mark W. Dewhirst Duke University
John B. Little
John B. Little Harvard University
Hatsumi Nagasawa
Hatsumi Nagasawa Colorado State University
John W. Kappler
John W. Kappler National Jewish Health
Frederik Wenz
Frederik Wenz University of Freiburg
Philippa Marrack
Philippa Marrack National Jewish Health
Pierre Sonveaux
Pierre Sonveaux Université Catholique de Louvain
Pei Zhong
Pei Zhong Duke University
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Andrew Thorburn
Andrew Thorburn University of Colorado Denver

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