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Biology and Biochemistry

D-Index
64
Citations
18149
World Ranking
9517
National Ranking
4201

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors

Overview

Richard Heller is affiliated with the University of South Florida in the United States. Their research spans several fields in the life sciences with a particular emphasis on biochemistry, genetics, molecular biology, and medicine. Their work intersects multiple subfields including biotechnology, oncology, molecular biology, immunology, and radiology, nuclear medicine, and imaging.

The scientist's main topics of research focus on microbial inactivation methods, CAR-T cell therapy research, plasma applications and diagnostics, immunotherapy and immune responses, transgenic plants and applications, virus-based gene therapy research, and RNA interference and gene delivery.

Frequent coauthors collaborating with Richard Heller include Loreé C. Heller, Guilan Shi, Siqi Guo, Chunqi Jiang, and Jody Synowiec.

Common publication venues for their work include Bioelectrochemistry, Cancer Research, Pharmaceutics, Scientific Reports, and the 2020 IEEE International Conference on Plasma Science (ICOPS).

Some recent papers by Richard Heller cover a range of topics and publication venues:

  • Biological factors of the tumour response to electrochemotherapy: Review of the evidence and a research roadmap, 2021, European Journal of Surgical Oncology
  • Potentiation of electrochemotherapy effectiveness by immunostimulation with IL-12 gene electrotransfer in mice is dependent on tumor immune status, 2021, Journal of Controlled Release
  • Synergistic Effects of an Atmospheric-Pressure Plasma Jet and Pulsed Electric Field on Cells and Skin, 2021, IEEE Transactions on Plasma Science
  • Reduction of plasmid vector backbone length enhances reporter gene expression, 2021, Bioelectrochemistry
  • IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models, 2021, Frontiers in Immunology

Richard Heller was recognized as a Fellow of the National Academy of Inventors in 2020.

Best Publications

  • Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

    Guilian Niu;Kenneth L Wright;Mei Huang;Lanxi Song

  • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

    Tianhong Wang;Guilian Niu;Marcin Kortylewski;Lyudmila Burdelya

  • The orderly progression of melanoma nodal metastases.

    Douglas Reintgen;C. Cruse;Karen Wells;Claudia Berman

  • Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma.

    Adil I. Daud;Ronald C. DeConti;Stephanie Andrews;Patricia Urbas

  • Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy.

    LM Mir;LF Glass;G Sersa;J Teissié

  • In vivo gene electroinjection and expression in rat liver

    Richard Heller;Mark Jaroszeski;Andrew Atkin;Darius Moradpour

  • Gene Therapy with Dominant-negative Stat3 Suppresses Growth of the Murine Melanoma B16 Tumor in Vivo

    Guilian Niu;Richard Heller;Robyn Catlett-Falcone;Domenico Coppola

  • Theory and in vivo application of electroporative gene delivery.

    Stella Somiari;Jill Glasspool-Malone;Joseph J. Drabick;Richard A. Gilbert

  • Electrochemotherapy: from the drawing board into medical practice

    Damijan Miklavčič;Barbara Mali;Bor Kos;Richard Heller

  • Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy

    Richard Heller;Mark J. Jaroszeski;L. Frank Glass;Jane L. Messina

  • Detection of submicroscopic lymph node metastases with polymerase chain reaction in patients with malignant melanoma.

    X Wang;R Heller;N VanVoorhis;C W Cruse

  • IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma.

    M.Lee Lucas;Loree Heller;Domenico Coppola;Richard Heller

  • Treatment of cutaneous and subcutaneous tumors with electrochemotherapy using intralesional bleomycin.

    Richard Heller;Mark J. Jaroszeski;Douglas S. Reintgen;A P A Chris Puleo

  • Method of treatment using electroporation-mediated delivery of drugs and genes

    Sukhendo B. Dev;Gunter A. Hofmann;Richard A. Gilbert;Yasuhiko Hayakawa

  • In vivo electroporation for gene therapy.

    Loree C Heller;Richard Heller

  • Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments.

    Angela M Bodles-Brakhop;Richard Heller;Ruxandra Draghia-Akli

  • Needle electrodes for mediated delivery of drugs and genes

    Gunter A. Hofmann;Richard A. Gilbert;Yasuhiko Hayakawa;Richard Heller

  • Clinical applications of electrochemotherapy.

    Richard Heller;Richard Gilbert;Mark J Jaroszeski

  • Electroporation Gene Therapy Preclinical and Clinical Trials for Melanoma

    Loree C Heller;Richard Heller

  • Novel electrode designs for electrochemotherapy

    Richard A Gilbert;Mark J Jaroszeski;Richard Heller

Frequent Co-Authors

Karl H. Schoenbach
Karl H. Schoenbach Old Dominion University
Douglas S. Reintgen
Douglas S. Reintgen University of South Florida
Domenico Coppola
Domenico Coppola Moffitt Cancer Center
Kenneth E. Ugen
Kenneth E. Ugen University of South Florida
Stephen J. Beebe
Stephen J. Beebe Old Dominion University
Jane L. Messina
Jane L. Messina University of South Florida
Adil Daud
Adil Daud University of California, San Francisco
David B. Weiner
David B. Weiner The Wistar Institute
Richard Jove
Richard Jove Nova Southeastern University
Huntington Potter
Huntington Potter University of Colorado Anschutz Medical Campus

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